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FD-IN-1

  Cat. No.:  DC43963  
Chemical Structure
1646682-14-5
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More than 5000 active chemicals with high quality for research!
Field of application
FD-IN-1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1646682-14-5
Synonyms: FD-IN-1
SMILES: O=C(O)CC1=CC=CC=C1OCC2=CC=CC(C3=CC([C@H](N)CO)=CC=C3)=C2
Formula: C23H23NO4
M.Wt: 377.43
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_27631_DC43963_1646682-14-5
COA
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Cat. No. Product name Field of application
DC47298 Lipoteichoic acid Lipoteichoic acid, a cell wall component of Staphylococcus aureus, activates the complement system via C3 induction and CD55 inhibition.
DC47058 Vemircopan Vemircopan is a complement factor D inhibitor.
DC46608 Compstatin control peptide TFA Compstatin control peptide TFA is a complement inhibitor that binds and inhibits cleavage of complement C3.
DC45525 POT-4 TFA POT-4 TFA (AL-78898A TFA), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 TFA can be used for age-related macular degeneration research.
DC45303 POT-4 POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration research
DC44839 Compstatin control peptide Compstatin control peptide is a complement inhibitor that binds and inhibits cleavage of complement C3.
DC43963 FD-IN-1 FD-IN-1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN
DC41847 AMY-101 acetate AMY-101 acetate (Cp40 acetate), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 acetate (Cp40 acetate) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation.
DC41798 TLQP-21 TFA TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions.
DC41797 TLQP-21 TLQP-21, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor 1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8 μM). TLQP-21 activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions.
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