Fresolimumab
Cat. No.: A537
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Chemical Structure
948564-73-6
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Field of application
Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease.
Cas No.: |
948564-73-6 |
pH value: |
Corresponds to reference standard: PASS |
Non-reduced CE-SDS: |
>95% |
SEC-HPLC: |
>95% |
Isoelectric Point: |
Corresponds to reference standard |
Osmolality: |
Corresponds to reference standard: PASS |
Peptide mapping: |
Corresponds to reference standard: PASS |
N-terminal sequence: |
Corresponds to reference standard: PASS |
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