L-368,899

  Cat. No.:  DC72128  
Chemical Structure
148927-60-0
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More than 5000 active chemicals with high quality for research!
Field of application
L-368,899 is an orally active and selective OT (oxytocin ) receptor antagonist, with IC50s of 8.9 and 26 nM for uterus of rat and human, respectively. L-368,899 can cross the blood-brain barrier (BBB). L-368,899 inhibits oxytocin-stimulated uterine contractions in rats and can be used in study of preterm labor.
Cas No.: 148927-60-0
Chemical Name: L-368,899
SMILES: O=S(C[C@]12[C@H](C[C@@H](CC2)C1(C)C)NC([C@@H](N)CCS(C)(=O)=O)=O)(N3CCN(C4=C(C=CC=C4)C)CC3)=O
Formula: C26H42N4O5S2
M.Wt: 554.77
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC70134 Oxytocin A peptide hormone and neuropeptide that is released into the bloodstream as a hormone in response to stretching of the cervix and uterus during labor and with stimulation of the nipples from breastfeeding.
DC72128 L-368,899 L-368,899 is an orally active and selective OT (oxytocin ) receptor antagonist, with IC50s of 8.9 and 26 nM for uterus of rat and human, respectively. L-368,899 can cross the blood-brain barrier (BBB). L-368,899 inhibits oxytocin-stimulated uterine contractions in rats and can be used in study of preterm labor.
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