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MC1 Precursor

  Cat. No.:  DC65839   Featured
Chemical Structure
1018480-97-1
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More than 5000 active chemicals with high quality for research!
Field of application
Precursor of MC1, is a vital component in the synthesis of MC1, a selective and potent COX-2 inhibitor. Radiolabeled MC1, [¹¹C]MC1, serves as a promising PET radioligand for imaging COX-2 expression in vivo. Its high selectivity, combined with its ability to non-invasively visualize COX-2 in disease states, makes it a valuable tool for research and clinical applications, particularly in neuroinflammation, cancer, and drug development.
Cas No.: 1018480-97-1
Chemical Name: 2-(4-methanesulfonylphenyl)-6-{[(thiophen-2-yl)m ethyl]amino}pyrimidin-4-ol
Synonyms: 2-(4-methanesulfonylphenyl)-6-{[(thiophen-2-yl)m ethyl]amino}pyrimidin-4-ol;4(3H)-Pyrimidinone, 2-[4-(methylsulfonyl)phenyl]-6-[(2-thienylmethyl)amino]-;BDBM50373581;CHEMBL272393;PD166222;EN300-6735765;2-(4-methanesulfonylphenyl)-6-{[(thiophen-2-yl)methyl]amino}pyrimidin-4-ol;2-(4-Methylsulfonylphenyl)-4-(thiophen-2-ylmethylamino)-1H-pyrimidin-6-one;1018480-97-1
SMILES: C1(C2=CC=C(S(C)(=O)=O)C=C2)=NC(NCC2SC=CC=2)=CC(=O)N1
Formula: C16H15N3O3S2
M.Wt: 361.43860077858
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
Cat. No. Product name Field of application
DC67437 PI-2620 precursor PI-2620 precursor is the precursor of PI2620. 18F-PI-2620 is a PET tracer with high binding affinity for aggregated tau, a key pathologic feature of Alzheimer disease (AD) and other neurodegenerative disorders.
DC60818 mono-Boc-Br MK-6240 Precursor mono-Boc-Br MK-6240 Precursor is the precusor of MK-6240.. (18)F]-MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs), exhibiting high specificity and selectivity for binding to NFTs .
DC67285 DOTA-Octreotide
DC67284 NOTA-NOC
DC60791 Cholestify Precursor Precursor of Cholestify,18F-Cholestify, which binds cytochrome P450 46A1, detected cholesterol breakdown in the mammalian brain. CYP46A1 converts cholesterol to 24-hydroxycholesterol, a form easily eliminated from the brain.
DC60790 DesMEM AZD4694 DesMEM AZD4694(AZD4694 Precursor 1)is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques.
DC66469 DOTA-NOC DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging.
DC66468 NOTA-octreotide NOTA-octreotide is a ligand for making [18F]AlF-NOTA-octreotide, which is a PET/CT imaging agent for somatostatin receptor imaging in neuroendocrine tumor patients
DC66467 F-PSMA 1007
DC66465 Pentanedioate Pentanedioate is a valuable starting material for the synthesis of PSMA inhibitors due to its flexible structure and functional groups that mimic natural PSMA ligands. By leveraging its chemical properties, researchers can develop potent and selective PSMA-targeting agents for diagnostic imaging, targeted therapy, and theranostic applications in prostate cancer and other PSMA-expressing malignancies. Its role in drug discovery highlights the importance of simple organic molecules in the development of advanced cancer therapies.
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