Mirikizumab
Cat. No.: A249
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Chemical Structure
1884201-71-1
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Field of application
Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 (IL-23). Mirikizumab binds to human and monkey IL-23 with high affinity, with Kd values of 21 pM and 55 pM, respectively. By inhibiting the binding of IL-23 to IL-23R, Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease.
Cas No.: |
1884201-71-1 |
pH value: |
Corresponds to reference standard: PASS |
Non-reduced CE-SDS: |
>95% |
SEC-HPLC: |
>95% |
Isoelectric Point: |
Corresponds to reference standard |
Osmolality: |
Corresponds to reference standard: PASS |
Peptide mapping: |
Corresponds to reference standard: PASS |
N-terminal sequence: |
Corresponds to reference standard: PASS |
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