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ML019 (SID 7969543)

  Cat. No.:  DC43801   Featured
Chemical Structure
868224-64-0
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More than 5000 active chemicals with high quality for research!
Field of application
SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 868224-64-0
Chemical Name: SID 7969543
Synonyms: Ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate;isoquinolinone scaffold, 2;F1808-0160;2-[2-[(2,3-DIHYDROBENZO[1,4]DIOXIN-6-YLCARBAMOYL)METHYL]-1-OXO-1,2-DIHYDROISOQUINOLIN-5-YLOXY]PROPIONIC ACID ETHYL ESTER;SID7969543;CHEMBL259067;AC1N2RVQ;ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-7-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate;Ethyl2-[[2-[2-[(2,3-Dihydro-1,4-benzodioxin-6-yl)amino]-2-oxoethyl]-1,2-dihydro-1-oxo-5-isoquinolinyl]oxy]propanoate;SID 7969543;ML019;Ethyl 2-[[2-[2-[(2,3-Dihydro-1,4-benzodioxin-6-yl)amino]-2-oxoethyl]-1,2-dihydro-1-oxo-5-isoquinolinyl]oxy]propanoate;ethyl 2-((2-(2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-2-oxoethyl)-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy)propanoate;SMR000017938;MLS000103673;MLS002152840;MLS006011674;GTPL5423;BDBM2;ETHYL 2-[[2-[2-[(2,3-DIHYDRO-BENZO[B][1,4]DIOXINE-6-YL)AMINO]-2-OXOETHYL]-1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL]OXY]PROPANOATE;S;ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate;ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate;HMS3263G15;HMS3263G15;HMS2246E14;HMS2246E14;cid_4076092;cid_4076092;MS-28223;MS-28223;Q27088800;Q27088800;BRD-A43885598-001-08-1;BRD-A43885598-001-08-1;SR-01000622833-4;SR-01000622833-4;HY-107404;HY-107404;BDBM28638;BDBM28638;ethyl 2-[(2-{[(2,3-dihydro-1,4-benzodioxin-6-yl)carbamoyl]methyl}-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy]propanoate;ethyl 2-[(2-{[(2,3-dihydro-1,4-benzodioxin-6-yl)carbamoyl]methyl}-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy]propanoate;NCGC00261682-01;NCGC00261682-01;SID7969543, >=98% (HPLC), solid;SID7969543, >=98% (HPLC), solid;DA-67584;DA-67584;Tox21_500997;Tox21_500997;ethyl 2-({2-[(2,3-dihydro-1,4-benzodioxin-6-ylcarbamoyl)methyl]-1-oxo-1,2-dihydroisoquinolin-5-yl}oxy)propanoate;ethyl 2-({2-[(2,3-dihydro-1,4-benzodioxin-6-ylcarbamoyl)methyl]-1-oxo-1,2-dihydroisoquinolin-5-yl}oxy)propanoate;LP00997;LP00997;G13291;G13291;SID-7969543;CS-0028417;SID-7969543;EX-A7587;CS-0028417;AKOS024457632;EX-A7587;CHEBI:91707;AKOS024457632;HMS3413N10;CHEBI:91707;868224-64-0;DTXSID90399071;HMS3413N10;HMS3677N10;868224-64-0;NCGC00081778-04;DTXSID90399071;NCGC00081778-02;HMS3677N10;HMS1654L06;NCGC00081778-04;NCGC00081778-02;SDCCGSBI-0633774.P001;HMS1654L06;NCGC00081778-03;SDCCGSBI-0633774.P001;NCGC00081778-03
SMILES: O(C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2C(N(C([H])=C([H])C=21)C([H])([H])C(N([H])C1C([H])=C([H])C2=C(C=1[H])OC([H])([H])C([H])([H])O2)=O)=O
Formula: C24H24N2O7
M.Wt: 452.4566
Purity: >98%
Sotrage: 0°C (short term), -20°C (long term), desiccated
MSDS
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MSDS_27414_DC43801_868224-64-0
COA
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Cat. No. Product name Field of application
DC33635 DODAP DODAP, also known as 1,2-Dioleoyl-3-dimethylammonium-propane, is a cationic lipid. It has been used as a component in liposomes that can be used to encapsulate siRNA, immunostimulatory oligodeoxynucleotides, antisense oligonucleotides, or chemotherapeutic agents for in vitro and in vivo delivery.
DC31074 Isopropyl myristate Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
DC74583 ZK53 ZK53 is a selective activator of mitochondrial caseinolytic protease P (HsClpP). It exhibits an EC50 of 1.37 μM for α-casein hydrolysis by HsClpP. ZK53 treatment allosterically activates HsClpP to uncontrollably degrade the essential mitochondrial proteins and is inactive toward bacterial ClpP proteins.
DC74576 Fluorofurimazine Fluorofurimazine is a novel furimazine analogue, with increased aqueous solubility enabling higher signal emission than furimazine for bioluminescence imaging. Fluorofurimazine enables higher substrate loading and improved optical imaging sensitivity in in-vivo.
DC74557 PREX-in1 PREX-in1 is a specific small-molecule inhibitor of P-Rex1 and P-Rex2 Rac-GEF activity with IC50 of 4.5 uM (P-Rex1 DHPH Rac-GEF activity) in liposome-based GEF assay, inhibits P-Rex1 and P-Rex2 through their catalytic DH domain.
DC74555 GYS32661 GYS32661 (GYS 32661) is a potent Rac inhibitor capable of inhibiting both Rac1 and Rac1b, inhibited activated Rac1 with IC50 of 1.18 uM in in vitro pull-down assays.
DC74539 L557-0155 L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.
DC74528 K284 K284 is a selective small molecule inhibitor of chitinase 3 like1 (CHI3L1) with strong binding affinity (Kd=-9.7 kcal·mol-1), inhibits lung metastasis by blocking IL-13Rα2-mediated JNK-AP-1 signals.
DC74247 AG-946 AG-946 (AG946) is a potent, allosteric activator of wild-type and mutant RBC-specific form of pyruvate kinase (PKR) with AC50 of 5 nM for human wild-type PK, 4.3 nM and 6.9 nM for mutated K410E and R510Q PK proteins, resepctively.
DC74241 Rebecsinib Rebecsinib (17S-FD-895) is a selective small-molecule inhibitor of splicing-mediated ADAR1 activation, prevents leukemia stem cell generation.
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