(+)-Muscarine (chloride)|cas 2303-35-7

Cas No.:	2303-35-7
Synonyms:	(+)-Muscarine (chloride)
SMILES:	C[C@H]1[C@H](O)C[C@@H](C[N+](C)(C)C)O1.[Cl-]
Formula:	C₉H₂₀NO₂^.Cl
M.Wt:	209.7
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

(+)-Muscarine is an agonist of muscarinic acetylcholine receptors that was originally found in A. muscaria.It induces spasms in isolated intestinal ileum from mouse, guinea pig, rabbit, dog, monkey, and horse, contraction of longitudinal uterine and bladder muscle strips from mouse, guinea pig, rabbit, rat, horse, and dog, and slows the heart rate of isolated guinea pig and rabbit atria. In vivo, (+)-muscarine induces bronchoconstriction in guinea pigs and rabbits as well as respiratory depression in rabbits and cats with minimum active doses (MADs) ranging from 1 to 5 μg/kg. It reduces blood pressure in cats, dogs, and rabbits and induces uterine, bladder, and intestinal contraction in cats and dogs. (+)-Muscarine (0.005-0.01 mg/kg) increases circling and pacing behaviors and induces fear aggression in cats.2 It has antinociceptive activity in rats in the hot plate and tail-flick tests.(+)-Muscarine also inhibits acetylcholinesterase (Ki = 220 μM).

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC47250	Nonanal	Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity.
DC47249	Piperitone	Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity.
DC47247	Tyrosylleucine TFA	Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47243	Dehydroglyasperin C	Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities.
DC47227	(−)-Myrtenal	(−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
DC47224	GPX4-IN-3	GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.
DC47179	Tyrosylleucine	Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47178	Mead acid	Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency.
DC47140	Yadanzioside K	Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
DC47105	Complanatoside B	Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects.