Ninerafaxstat

  Cat. No.:  DC47069   Featured
Chemical Structure
2254741-41-6
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More than 5000 active chemicals with high quality for research!
Field of application
Ninerafaxstat hifts cellular metabolism from fatty acid oxidation to glucose oxidation.Ninerafaxstat decreases fatty acid oxidation and improve overall mitochondrial respiration.Ninerafaxstat inhibit the growth and proliferation of cancer cells.
Cas No.: 2254741-41-6
Chemical Name: Ninerafaxstat
Synonyms: 2-(4-(2,3,4-Trimethoxybenzyl)piperazin-1-yl)ethyl nicotinate;0RB6V4E5XN;Ninerafaxstat;Ninerafaxstat [INN];2-(4-((2,3,4-Trimethoxyphenyl)methyl)piperazin-1-yl)ethyl pyridine-3-carboxylate;3-Pyridinecarboxylic acid, 2-(4-((2,3,4-trimethoxyphenyl)methyl)-1-piperazinyl)ethyl ester
SMILES: O(C(C1=C([H])N=C([H])C([H])=C1[H])=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2C([H])=C([H])C(=C(C=2OC([H])([H])[H])OC([H])([H])[H])OC([H])([H])[H])C([H])([H])C1([H])[H]
Formula: C22H29N3O5
M.Wt: 415.4828
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC31074 Isopropyl myristate Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
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DC74557 PREX-in1 PREX-in1 is a specific small-molecule inhibitor of P-Rex1 and P-Rex2 Rac-GEF activity with IC50 of 4.5 uM (P-Rex1 DHPH Rac-GEF activity) in liposome-based GEF assay, inhibits P-Rex1 and P-Rex2 through their catalytic DH domain.
DC74555 GYS32661 GYS32661 (GYS 32661) is a potent Rac inhibitor capable of inhibiting both Rac1 and Rac1b, inhibited activated Rac1 with IC50 of 1.18 uM in in vitro pull-down assays.
DC74539 L557-0155 L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.
DC74528 K284 K284 is a selective small molecule inhibitor of chitinase 3 like1 (CHI3L1) with strong binding affinity (Kd=-9.7 kcal·mol-1), inhibits lung metastasis by blocking IL-13Rα2-mediated JNK-AP-1 signals.
DC74247 AG-946 AG-946 (AG946) is a potent, allosteric activator of wild-type and mutant RBC-specific form of pyruvate kinase (PKR) with AC50 of 5 nM for human wild-type PK, 4.3 nM and 6.9 nM for mutated K410E and R510Q PK proteins, resepctively.
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