TG 100801|CAS 867331-82-6|DC Chemicals

Cas No.:	867331-82-6
Chemical Name:	TG 100801
Synonyms:	TG100801;TG-100801
SMILES:	C(OC1C=CC(Cl)=C(C2C=C(C)C3N=C(NC4C=CC(OCCN5CCCC5)=CC=4)N=NC=3C=2)C=1)(=O)C1C=CC=CC=1
Formula:	C₃₃H₃₀ClN₅O₃
M.Wt:	580.076

MSDS

Cat. No.	Product name	Field of application
DC7571	PD173955	PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth.
DC11954	JP-153	JP-153 (JP153) is a novel small molecule targets the Src-FAK-Paxillin signaling, inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473) in RECs; potently inhibits VEGF-induced proliferation and migration, inhibits retinal neovascularization in the murine oxygen-induced retinopathy model.
DC74421	TG 100801	The prodrug of TG 100572, a potent, dual receptor tyrosine kinase/Src kinase inhibitor with IC50 of 2-16 nM for VEGFR, FGFR and PDGFR, 0.1-5 nM for Src family.
DC70096	SRI-37264	SRI-37264 (SRI 37264) is a small molecule inhibitor of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck, blocks HIV-1 replication in macrophages and disrupts MHC-I downregulation.
DC49000	Fenlean	Fenlean, a natural squamosamide derivative, is a Src tyrosine kinase inhibitor. Fenlean can inhibit over-activated microglia and protect dopaminergic neurons. Fenlean can attenuate neuroinflammation in Parkinson's disease models.