DC49801 |
Evolocumab
|
Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR. Evolocumab can be used for the research of hypercholesterolemia and atherosclerotic cardiovascular diseases. |
DC72681 |
SPC4061
|
SPC4061 an antisense nucleotide, is a potent PCSK9 inhibitor. SPC4061 targets the lock-in nucleic acid (LNA) of PCSK9 for the study of hypercholesterolemia and related diseases. |
DC72680 |
PPACK II diTFA
|
PPACK II diTFA is an irreversible and specific glandular and plasma kallikreins inhibitor. |
DC72410 |
Ac-Phe-Gly-pNA
|
Ac-Phe-Gly-pNA is the chymotrypsin specific substrate. |
DC72409 |
AAF-CMK
|
AAF-CMK is a TPPII (tripeptidylpeptidase II) inhibitor, shows anti-tumor activity and induces apoptosis. AAF-CMK can be used in leukemia research. |
DC72231 |
Cyclotheonamide A
|
Cyclotheonamide A is a serine protease inhibitor (cyclic polypeptide), which can be obtained from marine sponges of the genus Theonella. Cyclotheonamide A shows potent inhibitory activity against trypsin (Ki=0.023 µM) and streptokinase (Ki=0.035 µM) and moderate inhibitory activity against human α-thrombin (Ki=0.18 µM). Cyclotheonamide A can be used in study of antithrombotic. |
DC72230 |
UAMC-00050
|
UAMC-00050 is a potent trypsin-like serine protease inhibitor. UAMC-00050 can be used in research of dry eye syndrome and ocular inflammation. |
DC71824 |
Tilpisertib fosmecarbil
|
Tilpisertib fosmecarbil is a potent serine/threonine kinase inhibitor. Tilpisertib fosmecarbil has anti-inflammatory activity. |
DC71823 |
Bezeparsen
|
Bezeparsen is a PCSK9 synthesis inhibitor. |
DC71558 |
Chymotrypsin
|
Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids. |