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YAP-TEAD Inhibitor 1 (Peptide 17)

  Cat. No.:  DC26213   Featured
Chemical Structure
1659305-79-9
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More than 5000 active chemicals with high quality for research!
Field of application
YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of?YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd= 40 nM).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1659305-79-9
Chemical Name: YAP-TEAD-IN-1 TFA
Synonyms: YAP-TEAD-IN-1 TFA;YAP-TEAD (Peptide 17).TFA;(S)-4-((S)-1-((S)-1-((S)-2-((3S,6S,9S,12R,18S,21S,24S,27S,30S,35AS)-18-((S)-2-((S)-1-((S)-2-Acetamido-3-methylbutanoyl)pyrrolidine-2-carboxamido)-3-(3-chlorophenyl)propanamido)-27-(4-aminobutyl)-9-benzyl-30-butyl-24-(3-guanidinopropyl)-6-(hydroxymethyl)-21-isobutyl-3-methyl-1,4,7,10,19,22,25,28,31-nonaoxodotriacontahydro-1H-pyrrolo[2,1-p][1,2,5,8,11,14,17,20,23,26,29]dithianonaazacyclotritriacontine-12-carboxamido)-6-aminohexanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)-5-amino-5-oxope
SMILES: C(F)(F)(F)C(=O)O.C(N1CCC[C@H]1C(=O)N[C@H](C(=O)N)CCC(=O)O)([C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(C1CSSCC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N[C@@]([H])(CCCC)C(=O)N2CCC[C@@]2([H])C(=O)N[C@@H](C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@H](CC2C=CC=CC=2)C(=O)N1)CCCCN)=O)CCCNC(N)=N)=O)CC(C)C)=O)NC(=O)[C@H](CC1C=CC=C(Cl)C=1)NC([C@@H]1CCCN1C(=O)[C@H](C(C)C)NC(=O)C)=O)=O)=O
Formula: C95H145ClF3N23O23S2
M.Wt: 2133.88632941246
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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