DC71666 |
MC-VA-PABC-MMAE |
MC-VA-PABC-MMAE is a drug-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE. |
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DC71667 |
Aminobenzenesulfonic auristatin E TFA |
Aminobenzenesulfonic auristatin E TFA is a drug-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic. |
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DC80073 |
Azido-PEG4-EV-Cit-PAB-MMAE
Featured
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Azido-PEG4-EV-Cit-PAB-MMAE is a precursor of antibody drug conjugate. |
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DC71923 |
Tomaymycin DM |
Tomaymycin DM, a DNA alkylator, is a derivative of Tomaymycin, it is a PBD dimer, which is attached to tumor targeting antibodies to create antibody-drug conjugates (ADCs). |
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DC71929 |
bisSP1 |
bisSP1 is an antibody drug conjugates linker. |
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DC71930 |
MDTF |
MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC71931 |
MDTF free acid |
MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC71932 |
NHS-SS-Ph |
NHS-SS-Ph is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC71949 |
MC-VA-PAB-Exatecan |
MC-VA-PAB-Exatecan is a drug-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan. MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity. |
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DC71950 |
Ac-Lys-Val-Cit-PABC-MMAE |
Ac-Lys-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitor MMAE. |
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DC71951 |
Aminobenzenesulfonic auristatin E-d8 |
Aminobenzenesulfonic auristatin E-d8 is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic. |
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DC72119 |
Deruxtecan analog 2 |
Deruxtecan analog 2 (example 9 P3) is a Deruxtecan analog. Deruxtecan analog 2 is a drug-linker conjugate composed of Camptothecin and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC.
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DC72257 |
TAM558 |
TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470, with antitumor activity. |
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DC72509 |
Sulfo-SPP sodium |
Sulfo-SPP sodium a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker. |
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DC72510 |
SC239 |
SC239 is a cleavable 2-aminophenyl hemiasterlin drug-linker. SC239 can be as the drug-linker for ADC. |
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DC72511 |
Mal-VC-PAB-PNP-CDN-A |
Mal-VC-PAB-PNP-CDN-A is a drug-linker conjugate for ADC. |
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DC72512 |
Mal-Val-Ala-PABA-cGAMP |
Mal-Val-Ala-PABA-cGAMP is a ADC linker that can be connected to a STING agonist. Mal-Val-Ala-PABA-cGAMP can be used for the synthesis of antibody-drug conjugates (ADCs). |
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DC72513 |
Fmoc-Ala-Ala-PAB |
Fmoc-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs). |
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DC72514 |
Mal-VC-PAB-PNP |
Mal-VC-PAB-PNP is a cleavable ADC Linker (ADC Linker). Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs). |
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DC72515 |
MC-Ala-Ala-PAB |
MC-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs). |
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DC72516 |
MP-Ala-Ala-PAB |
MP-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs). |
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DC72532 |
Fmoc-VAP-MMAE |
Fmoc-VAP-MMAE is a drug-linker conjugates for ADC. Fmoc-VAP-MMAE consists of an ADC linker and a tubulin inhibitor MMAE, with a protective Fmoc group. |
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DC72533 |
ATAC21 |
ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate. |
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DC72753 |
Gly-Cyclopropane-Exatecan |
Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan, a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro. |
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DC72757 |
MC-Gly-Gly-Phe-Boc |
MC-Gly-Gly-Phe-Boc is involved in the synthesis of Antibody-Drug Conjugates (ADCs) to Trastuzumab. MC-Gly-Gly-Phe-Boc can participate in cancer research. |
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DC72886 |
Dox-btn2 |
Dox-btn2 is a biotinylated derivative of Doxorubicin, with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm. |
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DC65699 |
Mal-propyl-Ala-Ala-Asn-PAB
Featured
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Mal-propyl-Ala-Ala-Asn(Trt)-PAB is a hetero bifunctional cross-linker, useful in antibody drug conjugation (ADC). |
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DC74469 |
ZD06519 |
ZD06519 is a novel camptothecin payload for antibody drug conjugates (ADCs) with highp ayload potency (~1 nM). |
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DC74470 |
SuO-Val-Cit-PAB-MMAE
Featured
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A drug-linker conjugate for antibody-drug conjugate by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the cleavable peptide SuO-Val-Cit-PAB.. |
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DC74471 |
EN106 derivative 1 |
EN106 derivative 1 is a EN106 derivative used for PROTAC design, EN106 is a covalent ligand and recruiter for FEM1B E3 ligase for targeted protein degradation. |
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