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Antibody Drug Conjugates

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Cat. No. Product Name Field of Application Chemical Structure
DC71666 MC-VA-PABC-MMAE MC-VA-PABC-MMAE is a drug-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE.
DC71667 Aminobenzenesulfonic auristatin E TFA Aminobenzenesulfonic auristatin E TFA is a drug-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic.
DC80073 Azido-PEG4-EV-Cit-PAB-MMAE Featured Azido-PEG4-EV-Cit-PAB-MMAE is a precursor of antibody drug conjugate.
DC71923 Tomaymycin DM Tomaymycin DM, a DNA alkylator, is a derivative of Tomaymycin, it is a PBD dimer, which is attached to tumor targeting antibodies to create antibody-drug conjugates (ADCs).
DC71929 bisSP1 bisSP1 is an antibody drug conjugates linker.
DC71930 MDTF MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC71931 MDTF free acid MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC71932 NHS-SS-Ph NHS-SS-Ph is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC71949 MC-VA-PAB-Exatecan MC-VA-PAB-Exatecan is a drug-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan. MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity.
DC71950 Ac-Lys-Val-Cit-PABC-MMAE Ac-Lys-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitor MMAE.
DC71951 Aminobenzenesulfonic auristatin E-d8 Aminobenzenesulfonic auristatin E-d8 is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic.
DC72119 Deruxtecan analog 2 Deruxtecan analog 2 (example 9 P3) is a Deruxtecan analog. Deruxtecan analog 2 is a drug-linker conjugate composed of Camptothecin and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC.
DC72257 TAM558 TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470, with antitumor activity.
DC72509 Sulfo-SPP sodium Sulfo-SPP sodium a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.
DC72510 SC239 SC239 is a cleavable 2-aminophenyl hemiasterlin drug-linker. SC239 can be as the drug-linker for ADC.
DC72511 Mal-VC-PAB-PNP-CDN-A Mal-VC-PAB-PNP-CDN-A is a drug-linker conjugate for ADC.
DC72512 Mal-Val-Ala-PABA-cGAMP Mal-Val-Ala-PABA-cGAMP is a ADC linker that can be connected to a STING agonist. Mal-Val-Ala-PABA-cGAMP can be used for the synthesis of antibody-drug conjugates (ADCs).
DC72513 Fmoc-Ala-Ala-PAB Fmoc-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
DC72514 Mal-VC-PAB-PNP Mal-VC-PAB-PNP is a cleavable ADC Linker (ADC Linker). Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).
DC72515 MC-Ala-Ala-PAB MC-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
DC72516 MP-Ala-Ala-PAB MP-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
DC72532 Fmoc-VAP-MMAE Fmoc-VAP-MMAE is a drug-linker conjugates for ADC. Fmoc-VAP-MMAE consists of an ADC linker and a tubulin inhibitor MMAE, with a protective Fmoc group.
DC72533 ATAC21 ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate.
DC72753 Gly-Cyclopropane-Exatecan Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan, a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro.
DC72757 MC-Gly-Gly-Phe-Boc MC-Gly-Gly-Phe-Boc is involved in the synthesis of Antibody-Drug Conjugates (ADCs) to Trastuzumab. MC-Gly-Gly-Phe-Boc can participate in cancer research.
DC72886 Dox-btn2 Dox-btn2 is a biotinylated derivative of Doxorubicin, with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm.
DC65699 Mal-propyl-Ala-Ala-Asn-PAB Featured Mal-propyl-Ala-Ala-Asn(Trt)-PAB is a hetero bifunctional cross-linker, useful in antibody drug conjugation (ADC).
DC74469 ZD06519 ZD06519 is a novel camptothecin payload for antibody drug conjugates (ADCs) with highp ayload potency (~1 nM).
DC74470 SuO-Val-Cit-PAB-MMAE Featured A drug-linker conjugate for antibody-drug conjugate by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the cleavable peptide SuO-Val-Cit-PAB..
DC74471 EN106 derivative 1 EN106 derivative 1 is a EN106 derivative used for PROTAC design, EN106 is a covalent ligand and recruiter for FEM1B E3 ligase for targeted protein degradation.

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