| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC28504 | mDPR(Boc)-Val-Cit-PAB | mDPR(Boc)-Val-Cit-PAB is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). |
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| DC28505 | Mal-PEG4-Val-Cit-PAB | Mal-PEG4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-Val-Cit-PAB is used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28506 | DBCO-(PEG2-Val-Cit-PAB)2 | DBCO-(PEG2-Val-Cit-PAB)2 is a dual cleavable ADC linker for antibody-drug conjugates (ADCs). |
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| DC28507 | Dimethyl-SGD-1882 | Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly potent DNA alkylator, and is used as an antibody-drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylator which inhibits DNA replication. |
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| DC28508 | SC-VC-PAB-MMAE | SC-VC-PAB-MMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB. |
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| DC28509 | DBCO-(PEG2-VC-PAB-MMAE)2 | DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. |
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| DC28510 | DBCO-PEG4-VC-PAB-DMEA-PNU-159682 | DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682. |
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| DC28511 | DBCO-NHCO-PEG4-NH-Boc | DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28512 | DBCO-PEG5-NHS ester | DBCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28513 | Mal-PEG1-NHS ester | Mal-PEG1-NHS ester is a cleavable and PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28516 | Amino-PEG6-alcohol | Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28518 | Aminooxy-PEG3-azide | Aminooxy-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-C2-PEG3-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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| DC28519 | Aminooxy-PEG2-alcohol | Aminooxy-PEG2-alcohol is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-PEG2-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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| DC28520 | Biotin-PEG2-acid | Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28521 | Mal-PEG1-acid | Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs) |
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| DC28523 | Propargyl-PEG3-NHS ester | Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28524 | Propargyl-PEG3-acid | Propargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA and Propargyl-PEG3-acid. |
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| DC28525 | Propargyl-PEG5-amine | Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
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| DC28560 | Tr-PEG6-OH | Tr-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28561 | Phe-Lys(Trt)-PAB | Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs). |
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| DC28562 | Fmoc-Phe-Lys(Trt)-PAB-PNP | Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28564 | Phe-Lys(Fmoc)-PAB | Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs). |
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| DC28566 | PDB-Pfp | PDB-Pfp is a reducible ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28567 | SPDMV Featured | SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs). |
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| DC28568 | SPDMB | SPDMB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs). |
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| DC28569 | SPDB-sulfo | SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) . |
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| DC28570 | PDdB-Pfp | PDdB-Pfp is a reducible ADC linker used for the agents that target for the extracellular loop 1 (ECL1) of TM4SF1 (transmembrane 4 L6 family member 1). |
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| DC28571 | SPDMV-sulfo | SPDMV-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs). |
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| DC28604 | S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate | S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes. |
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| DC28615 | m-PEG7-CH2COOH | m-PEG7-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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