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Antibody Drug Conjugates

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Cat. No. Product Name Field of Application Chemical Structure
DC40455 Puwainaphycin F Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization.
DC40467 Mytoxin B Mytoxin B is an ADC cytotoxin. Mytoxin B is a satratoxin-type trichothecene macrolide and is similar to the effect of LY294002. Mytoxin B induces cell apoptosis via PI3K/Akt pathway.
DC40468 Mc-VC-PAB-SN38 Featured Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs).
DC40469 Muscotoxin A Muscotoxin A is an?ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death.
DC40473 (R)-8-Azido-2-(Fmoc-amino)octanoic acid (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40475 DMAC-SPDB-sulfo DMAC-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40476 Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40477 Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40590 DBCO-PEG4-MMAF Featured DBCO-PEG4-MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the cleavable linker DBCO-PEG4.
DC40602 Tetrazine-Ph-SS-amine Tetrazine-Ph-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40612 4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene 4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40613 Propargyl-C8-amido-PEG2-NHS ester Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40614 Maleimide-DOTA Featured Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40616 Dimethylamine-SPDB Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40617 SPDP-sulfo SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40618 Mal-CO-PEG5-NHS ester Mal-CO-PEG5-?NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40619 Mal-Ph-CONH-PEG4-NHS ester Mal-Ph-CONH-PEG4-?NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40620 Ald-Ph-amido-PEG11-C2-NH2 Ald-Ph-amido-PEG11-C2-NH2 is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40621 NO2-SPP-sulfo NO2-SPP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40622 NO2-SPDB-sulfo NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40623 NO2-SPDMV-sulfo NO2-SPDMV-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40624 DMAC-SPDB DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40631 Ald-Ph-amido-PEG11-NH-Boc Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40632 Cyclooctyne-O-amido-PEG2-PFP ester Cyclooctyne-O-amido-PEG2-PFP ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40633 Mal-amido-PEG3-C1-PFP ester Mal-amido-PEG3-C1-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40634 Cyclooctyne-O-amido-PEG3-PFP ester Cyclooctyne-O-amido-PEG3-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40635 Cyclooctyne-O-amido-PEG4-PFP ester Cyclooctyne-O-amido-PEG4-PFP ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40636 Ald-Ph-amido-PEG3-NHS ester Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40637 Mal-PEG3-C1-NHS ester Mal-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40638 Mal-amido-PEG3-C1-NHS ester Mal-amido-PEG3-C1-?NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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