DC40455 |
Puwainaphycin F |
Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization. |
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DC40467 |
Mytoxin B |
Mytoxin B is an ADC cytotoxin. Mytoxin B is a satratoxin-type trichothecene macrolide and is similar to the effect of LY294002. Mytoxin B induces cell apoptosis via PI3K/Akt pathway.
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DC40468 |
Mc-VC-PAB-SN38
Featured
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Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40469 |
Muscotoxin A |
Muscotoxin A is an?ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death. |
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DC40473 |
(R)-8-Azido-2-(Fmoc-amino)octanoic acid |
(R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40475 |
DMAC-SPDB-sulfo |
DMAC-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40476 |
Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 |
Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40477 |
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc |
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40590 |
DBCO-PEG4-MMAF
Featured
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DBCO-PEG4-MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the cleavable linker DBCO-PEG4. |
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DC40602 |
Tetrazine-Ph-SS-amine |
Tetrazine-Ph-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40612 |
4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene |
4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40613 |
Propargyl-C8-amido-PEG2-NHS ester |
Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40614 |
Maleimide-DOTA
Featured
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Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40616 |
Dimethylamine-SPDB |
Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40617 |
SPDP-sulfo |
SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40618 |
Mal-CO-PEG5-NHS ester |
Mal-CO-PEG5-?NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40619 |
Mal-Ph-CONH-PEG4-NHS ester |
Mal-Ph-CONH-PEG4-?NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40620 |
Ald-Ph-amido-PEG11-C2-NH2 |
Ald-Ph-amido-PEG11-C2-NH2 is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40621 |
NO2-SPP-sulfo |
NO2-SPP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40622 |
NO2-SPDB-sulfo |
NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40623 |
NO2-SPDMV-sulfo |
NO2-SPDMV-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40624 |
DMAC-SPDB |
DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40631 |
Ald-Ph-amido-PEG11-NH-Boc |
Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40632 |
Cyclooctyne-O-amido-PEG2-PFP ester |
Cyclooctyne-O-amido-PEG2-PFP ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40633 |
Mal-amido-PEG3-C1-PFP ester |
Mal-amido-PEG3-C1-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40634 |
Cyclooctyne-O-amido-PEG3-PFP ester |
Cyclooctyne-O-amido-PEG3-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40635 |
Cyclooctyne-O-amido-PEG4-PFP ester |
Cyclooctyne-O-amido-PEG4-PFP ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40636 |
Ald-Ph-amido-PEG3-NHS ester |
Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40637 |
Mal-PEG3-C1-NHS ester |
Mal-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC40638 |
Mal-amido-PEG3-C1-NHS ester |
Mal-amido-PEG3-C1-?NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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