| DC44017 |
GSK-3/CDK5/CDK2-IN-1 |
GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer, and neurodegenerative diseases. |
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| DC44090 |
ddGTP |
ddGTP (2',3'-Dideoxyguanosine 5'-triphosphate) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. |
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| DC44106 |
M2N12
Featured
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M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC50 value of 0.09 μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC50 values of 0.53 μM and 1.39 μM, respectively. M2N12 has anti-tumor activity and can be used for cancer research. |
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| DC44124 |
TAS-119
Featured
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TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC50 of 95 nM). TAS-119 has potent antitumor activites. |
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| DC44125 |
DMT-dC(bz) Phosphoramidite |
DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA. |
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| DC44126 |
DMT-dT Phosphoramidite |
DMT-dT Phosphoramidite is typically used in the synthesis of DNA. |
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| DC44127 |
DMT-dU-CE Phosphoramidite |
DMT-dU-CE Phosphoramidite is a nucleoside molecule that can be used in DNA synthesis and DNA sequencing. |
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| DC44128 |
DMT-dG(ib) Phosphoramidite |
DMT-dG(ib) Phosphoramidite is typically used in the synthesis of DNA. |
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| DC44129 |
DMT-dA(bz) Phosphoramidite |
DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA. |
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| DC44130 |
Deoxycytidine triphosphate trisodium salt |
Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. |
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| DC44131 |
7-Deaza-2'-deoxy-7-iodoadenosine |
7-Deaza-2'-deoxy-7-iodoadenosine is a modified oligonucleotide containing 7-Deazaadenine. |
|
| DC44132 |
ddTTP |
ddTTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. |
|
| DC44133 |
Deoxyguanosine triphosphate trisodium salt |
Deoxyguanosine triphosphate (dGTP) trisodium salt is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification. |
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| DC44134 |
ddCTP |
ddCTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. |
|
| DC44135 |
5-Propargylamino-dCTP |
5-Propargylamino-dCTP is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. |
|
| DC44136 |
5-Propargylamino-ddCTP |
5-Propargylamino-ddCTP, a nucleoside molecule that can be used to synthesis of cyanine dye-nucleotide conjugate which is used in nucleic acid labeling or sequence analysis. |
|
| DC44137 |
5-Propargylamino-ddUTP
Featured
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5-Propargylamino-ddUTP, a nucleoside molecule that can be used to synthesis of cyanine dye-nucleotide conjugate which is used in nucleic acid labeling or sequence analysis. |
|
| DC44138 |
Thymidine-5'-triphosphate trisodium salt |
Thymidine-5'-triphosphate (dTTP) trisodium salt is one of the four natural deoxynucleotides. Thymidine-5'-triphosphate trisodium salt is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and reverse transcriptase. |
|
| DC44139 |
PluriSIn #2 |
PluriSIn #2 is a selective transcriptional inhibitor of topoisomerase II α (TOP2A). PluriSIn #2 is a compound that selectively eliminates undifferentiated human pluripotent stem cells (hPSCs). |
|
| DC44517 |
CDK6/9-IN-1 |
CDK6/9-IN-1 (compound 66) is an orally active active and dual CDK 6 and CDK 9 inhibitor, with IC50 values of 40.5 nM and 39.5 nM for CDK6 anmd CDK9, respectively. |
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| DC44518 |
CDK7-IN-3
Featured
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CDK7-IN-3 is a selective CDK7 inhibitor with a KD of 0.059 nM. CDK7-IN-3 shows poor inhibition on CDK2 (Ki=390 nM), CDK9 (Ki=290 nM), CDK12 (Ki=78 nM). CDK7-IN-3 induce apoptosis in tumor cells and has antitumor activity. |
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| DC44543 |
CCT241533 dihydrochloride |
CCT241533 dihydrochloride is a potent and selective ATP competitive inhibitor of CHK2 with an IC50 of 3 nM and Ki of 1.16 nM. |
|
| DC44544 |
1-Hydroxyanthraquinone |
1-Hydroxyanthraquinone, a naturally occurring compound with oral activity from some plants like Tabebuia avellanedae, exhibits carcinogenic effect. |
|
| DC44545 |
Bz-rA Phosphoramidite |
Bz-rA Phosphoramidite is used for ribonucleotides modification. |
|
| DC44546 |
Ac-rC Phosphoramidite |
Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA). |
|
| DC44547 |
LDN-209929 dihydrochloride
Featured
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LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor (IC50=55 nM) with180-fold selectivity verses DYRK2 (IC50=9.9 μM). LDN-209929 is a optimized analogue of LDN-192960 . |
|
| DC44548 |
Mps1-IN-1 dihydrochloride |
Mps1-IN-1 dihydrochloride is a potent, selective and ATP-competitive Mps1 kinase inhibitor, with an IC50 and a Kd of 367 nM and 27 nM. |
|
| DC44549 |
Purine riboside triphosphate |
Purine riboside triphosphate is a triphosphate derivative of purine riboside. Purine riboside is a naturally occurring base analog which closely resembles adenosine. Purine riboside inhibits carcinogenic growth. Purine riboside strongly inhibits RNA and D |
|
| DC44550 |
2′-Deoxy-2′-fluoroadenosine |
2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-flu |
|
| DC44551 |
Wistin |
Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist. |
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