Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Endogenous Metabolite
Cat. No. Product name CAS No.
DC47032 3-Oxo-4,6-choladien-24-oic acid

3-Oxo-4,6-choladien-24-oic acid is an endogenous metabolite. 3-Oxo-4,6-choladien-24-oic acid exsists in the urine of patients with hepatobiliary disease.

88179-71-9
DC47034 Ebaresdax

Ebaresdax can inhibit peroxynitrite oxidation derived by SIN-1 and peroxynitrite mediated Cytotoxicity with IC50s of 3.7±0.80 and 0.13±0.02 uM, respectively.

1334471-39-4
DC47040 Larsucosterol

Larsucosterol is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.

884905-07-1
DC47095 Larsucosterol sodium

Larsucosterol sodium is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.

1174047-40-5
DC47116 Deutarserine

Deutarserine is a deuterium modified analog of endogenous D-serine (CTP 692), which is used in the research of adults with schizophrenia.

103292-62-2
DC47141 Triiodothyronine sulfate

Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.

31135-55-4
DC47214 Phosphoribosyl pyrophosphate pentasodium

Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP.

108321-05-7
DC47664 Indole-3-acetaldehyde

Indole-3-acetaldehyde inhibits Escherichia coli O157:H7 biofilm formation.

2591-98-2
DC47665 4-Hydroxytryptamine creatinine sulfate

4-Hydroxytryptamine creatinine sulfate, a tryptamine derivative, is a neurotransmitter agonist.

55206-11-6
DC47666 NMTCA

NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid. NMTCA can be used as an indicator of endogenous nitrosation by gas chromatography-thermalenergyanalysis.

103659-08-1
DC47880 trans-Urocanic acid

trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function.

3465-72-3
DC47895 Sphinganine 1-phosphate

Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiological processes.

19794-97-9
DC47959 Lignoceric acid

Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research.

557-59-5
DC48057 AFMK

AFMK, antioxidant metabolite of Melatonin, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. AFMK is a poorer scavenger. The pKa of AFMK at physiological pH is 8.7. Antioxidant capacity. AFMK improves the anti-tumor effect of Gemcitabine in PANC-1 cells through the modulation of apoptotic pathway.

52450-38-1
DC48067 1,7-Dimethyluric acid

1,7-Dimethyluric acid is the metabolite of caffeine.

33868-03-0
DC48236 4β-Hydroxycholesterol

4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation.

17320-10-4
DC48237 Dihomo-γ-Linolenic acid methyl ester

Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is mainly metabolized to an anti-inflammatory eicosanoid, prostaglandin (PG) E1, via the cyclooxygenase (COX) pathway. Anti-inflammatory and anti-proliferative effects.

21061-10-9
DC48238 10(S),17(S)-DiHDHA

Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities.

871826-47-0
DC48239 12-OxoETE

12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via leukotriene B4 receptor or a common activation sequence.

108437-64-5
DC48240 Pregnanediol 3-glucuronide

Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species.

1852-49-9
DC48241 p-Cresyl sulfate

p-Cresyl Sulfate, a major uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver, existed in the blood of patients with chronic kidney disease (CKD).

3233-58-7
DC48242 ω-Muricholic Acid

ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.

6830-03-1
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