Cat. No. | Product name | CAS No. |
DC8057 |
S-Etomxir
Featured
S isomer of R-Etomoxir |
828934-43-6 |
DC7882 |
S0859
Featured
S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM). |
1019331-10-2 |
DC10395 |
S107
Featured
S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels. |
927871-76-9 |
DC11030 |
S119-8
Featured
S119-8 is a novel broad spectrum inhibitor of influenza virus replication (IC50=1.43 nM) by targeting the viral Nucleoprotein (NP), with no detectable cytotoxicity (CC50>50 uM). |
443639-96-1 |
DC12546 |
S18-000003
Featured
S18-000003 (S18-000003) is a potent, selective, orally bioavailable RORγt inhibitor with IC50 of 29 nM (hRORγt, GAL4), shows no significant activity against RORα, RORβ and LXRα/β(IC50>10 uM). |
2068119-11-7 |
DC7274 |
S1RA
Featured
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
878141-96-9 |
DC9264 |
S1RA hydrochloride
Featured
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
1265917-14-3 |
DC11455 |
Bz-Ile-Glu-Gly-Arg-pNA acetate salt
Featured
S-2222 is a chromogenic substrate for Factor Xa. |
59068-47-2 |
DC9807 |
S-2238(Thrombin Substrate)
Featured
S-2238 is specific to thrombin, is a short peptide covalently bound to pNA (4-nitroaniline). |
115388-96-0 |
DC10811 |
S23
Featured
S23 is a novel Selective Androgen Receptor Modulator(SARM) |
1010396-29-8 |
DC12622 |
S29434
Featured
S29434 (S 29434) is a highly potent, selective, cell-active inhibitor of Quinone reductase 2 (QR2) with IC50 of 5-16 nM, shows good selectivity for QR2 over QR1. |
874484-20-5 |
DC1033 |
S3I-201 (NSC-74859)
Featured
S3I-201 (NSC 74859) is a Stat3 inhibitor with IC50 of 86 μM. |
501919-59-1 |
DC11265 |
S49076 (hydrochloride)
Featured
S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. |
1265966-31-1 |
DC10071 |
S49076
Featured
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM. |
1265965-22-7 |
DC12163 |
S55746 (BLC201)
Featured
S55746 (BLC201) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 (BLC201) has antitumor activity with low toxicity[1]. |
1448584-12-0 |
DC10137 |
S63845
Featured
S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor; binds human MCL1 with a Kd of 0.19 nM. |
1799633-27-4 |
DC8529 |
S6K-18
Featured
S6K-18 is a highly selective inhibitor of S6K1, with an IC50 of 52nM. |
1265789-88-5 |
DC8506 |
S-99
Featured
S-99 inhibits LPS-induced TNFa release assay in vivo |
1124381-69-6 |
DC8227 |
SA4503 2HCl
Featured
SA4503 is a selective sigma 1 receptor(σ1R) agonist; high affinity for the sigma 1 receptor subtype labeled by (+)-[3H]pentazocine (IC50 = 17.4 +/- 1.9 nM); 100-fold less affinity for the sigma 2 receptor. |
165377-44-6 |
DC8444 |
Sabutoclax
Featured
Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively. |
1228108-65-3 |
DC8099 |
Saclofen
Featured
Saclofen is a selective GABAB antagonist. |
125464-42-8 |
DCAPI1520 |
S-adenosyl-L-methionine(Ademetionine)
Featured
Ademetionine, also known as AdoMet; MSI-195; SAMe, S-adenosylmethionine, is a PDE4B inhibitor potentially for treatment of primary biliary cirrhosis and major depressive disorder. Ademetionine is a ubiquitous metabolite present in all cells and biological fluids, and serves as a methyl donor in a multitude of different methylation reactions involving proteins, phospholipids, catecholamines and DNA. Pharmaceutical preparations of some stable salts of SAMe are available for parenteral and oral use in humans, and have been shown to increase plasma and cerebrospinal fluid SAMe concentrations. |
29908-03-0 |