S-adenosyl-L-methionine(Ademetionine)

  Cat. No.:  DCAPI1520   Featured
Chemical Structure
29908-03-0
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More than 5000 active chemicals with high quality for research!
Field of application
Ademetionine, also known as AdoMet; MSI-195; SAMe, S-adenosylmethionine, is a PDE4B inhibitor potentially for treatment of primary biliary cirrhosis and major depressive disorder. Ademetionine is a ubiquitous metabolite present in all cells and biological fluids, and serves as a methyl donor in a multitude of different methylation reactions involving proteins, phospholipids, catecholamines and DNA. Pharmaceutical preparations of some stable salts of SAMe are available for parenteral and oral use in humans, and have been shown to increase plasma and cerebrospinal fluid SAMe concentrations.
Cas No.: 29908-03-0
SMILES: O=C([O-])[C@@H](N)CC[S+](C[C@H]1O[C@@H](N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O)C
Formula: C15H22N6O5S
M.Wt: 398.44
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: S-adenosyl-L-methionine(Ademetionine) is an intermediate metabolite of methionine. Its involvement in methylation assists in cellular growth and repair, maintains the phospho-bilipid layer in cell membranes. It also helps in the maintenance of the action of several hormones and neurotransmitters that affect mood.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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