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Cat. No. Product Name Field of Application Chemical Structure
DC66113 DSPE-PEG-FA Featured Phospholipid polyethylene glycol folate (dspe-peg-fa), carboxyl group and amino group form amide bond. This reaction makes folate ligand attach to protein, antibody, peptide or particle surface. Pegylated folate has good water solubility and bioactivity. Folate functionalized substrates have been used for targeted drug delivery, imaging and bioassay. DSPE (1,2-distearyl-sn-glycerin-3-phosphate ethanolamine) is a saturated 18 carbon phospholipid, which is commonly used in the synthesis of liposomes. Polyethylene glycol (PEG) - coupled DSPE is hydrophilic and can be used for drug delivery, gene transfection and biomolecular modification.
DC66114 FAPI-46 Featured FAPI-46 is a highly promising FAP-targeted radiotracer with superior tumor uptake and prolonged accumulation, making it an excellent tool for imaging a wide range of cancers. Its versatility, combined with its potential for theragnostic applications, positions FAPI-46 as a valuable asset in the field of oncology, enabling improved diagnosis, staging, and treatment monitoring for patients with FAP-expressing tumors.
DC66115 DSPE-PEG-OH Featured DSPE-PEG-OH, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Additionally, DSPE-PEG-OH, MW 2000 can also be used for drug delivery.
DC66116 DSPE-PEG-FITC Featured DSPE-PEG-FITC, is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
DC66117 DSPE-PEG-Rhodamine Featured DSPE-PEG-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
DC66118 DSPE-PEG-Galactose Featured Long circulating liposomes were obtained by modifying the surface of liposomes with polyethylene glycol, which could prolong the half-life of liposomes, improve its stability in blood circulation, and change the biological distribution of liposomes.
DC66119 DSPE-MPEG Featured 2-Distearoyl-sn-Glycero-3-Phosphoethanolamine(DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol, which has hydrophilicity and hydrophobicity. Polyethylene glycol phospholipid liposomes can be used for drug delivery, gene transfection and vaccine delivery. Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation. These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides,Liposomes.
DC66120 DSPE-SE-SE-mPEG Featured The diselenide bond is an important chemical bond formed by two selenium atoms sharing a pair of electrons. Because the electronegativity of selenium atom is low, the bond energy of diselenide bond is low, so it has the characteristics of strong reactivity and easy to break. In polymer materials, the dynamic chemical properties of diselenide bond make it have a wide application prospect. The dynamic chemical properties of diselenide bond are mainly manifested in its easy fracture and formation. In polymer materials, diselenide bond fracture can be achieved by external stimuli (such as light, heat, electricity, etc.) or chemical reactions. For example, through the action of photosensitizer initiator, polymer materials containing diselenide bonds can be broken under ultraviolet irradiation, so as to achieve controlled degradation of materials. In addition to breaking, diselenide bonds can also form new bonds. In polymer materials, diselenide bonds can form new bonds by free radical reaction or nucleophilic substitution reaction. For example, through free radical reactions, polymer materials containing diselenide bonds can be reacted with other free radical reactants to form new bonds and achieve cross-linking or modification of materials. In addition, diselenide bonds can also form new bonds through nucleophilic substitution reactions, such as in the presence of nucleophilic reagents, diselenide bonds can be replaced, so as to achieve the functionalization or modification of materials.
DC66121 DSPE-SE-SE-PEG-NHS Featured
DC66122 DSPE-SE-SE-PEG-MAL Featured
DC66123 DSPE-SE-SE-PEG-NH2 Featured
DC66124 DSPE-SE-SE-PEG-SH Featured
DC66125 DSPE-SE-SE-PEG-COOH Featured
DC66126 DSPE-SS-PEG-N3 Featured Phospholipids are commonly used polymeric gene carriers. DSPE with high molecular weight can effectively compound DNA, and has strong buffered capacity under endosomal pH conditions, showing good transfection efficiency for a variety of cells. However,DAPE is not easily degraded, and high molecular weight DAPE as a gene carrier may lead to short - or long-term cytotoxicity.
DC66127 DSPE-SS-PEG-Galactose Featured
DC66128 DSPE-SS-PEG-Mannose Featured Phospholipids are commonly used polymeric gene carriers. DSPE with high molecular weight can effectively compound DNA, and has strong buffered capacity under endosomal pH conditions, showing good transfection efficiency for a variety of cells. However,DAPE is not easily degraded, and high molecular weight DAPE as a gene carrier may lead to short - or long-term cytotoxicity.
DC60589 ABBV-CLS-484 (AC-484) Featured ABBV-CLS-484 (AC-484) is a novel PTPN2/N1 inhibitor with IC50 of 2.2 nM. AC-484 improves oral bioavailability across different species.
DC66129 Hynic-toc Featured
DC66130 Oclacitinib maleate Featured Oclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC50 's ranging from 36 to 249 nM.
DC66131 DSPE-SS-PEG-CY3 Featured
DC66132 DSPE-SS-PEG-CY7 Featured
DC66133 DSPE-SS-PEG-CY5.5 Featured
DC66134 DSPE-SS-PEG-CY5 Featured
DC66135 DSPE-SS-PEG-Silane Featured
DC66136 DSPE-SS-PEG-CHO Featured
DC66137 DSPE-SS-PEG-OPSS Featured
DC66138 DSPE-SS-PEG-RB Featured
DC66139 DSPE-SS-PEG-Biotin Featured
DC66140 DSPE-SS-PEG-FA Featured
DC66141 DSPE-SS-PEG-COOH Featured

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