| DC66205 |
Muscimol Hydrobromide
Featured
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Muscimol Hydrobromide is a GABAA receptor agonist. |
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| DC66206 |
DMPE-PEG-SH
Featured
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DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability. |
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| DC66207 |
DMPE-PEG-OH
Featured
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DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability. |
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| DC66208 |
DMPE-PEG-NHS
Featured
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DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability. |
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| DC66209 |
DMPE-PEG-COOH
Featured
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DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability. |
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| DC66210 |
DMPE-PEG-MAL
Featured
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DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability. |
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| DC66211 |
DMPE-PEG-NH2
Featured
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DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability. |
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| DC66212 |
DMPE-PEG-Biotin
Featured
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DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability. |
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| DC66213 |
DOPE-PEG-ICG
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66214 |
DOPE-PEG-RB
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66215 |
DOPE-PEG-CY3
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66216 |
DOPE-PEG-Cy5 (MW 2000)
Featured
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B23&" is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B23&"can be used in drug delivery research. |
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| DC66217 |
DOPE-PEG-Cy5.5 (MW 2000)
Featured
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B19&" is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B19&"can be used in drug delivery research." |
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| DC66218 |
DOPE-PEG-FITC
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC60591 |
Fmoc-Gly-Gly-OH
Featured
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Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC66224 |
DOPE-PEG-CY7
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers.
Cy7 emits at 750 nm and has a maximum absorption peak at about 773 nm. Cyanine dye is often used in biomolecular labeling, fluorescence imaging and other fluorescent biological analysis, and Cy7-labeled PEG derivatives can be used to track biomolecules due to their strong red light fluorescence. |
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| DC66225 |
DOPE-PEG-N3
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66226 |
DOPE-PEG-NBD
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66227 |
DOPE-PEG-Alkyne
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66228 |
DOPE-PEG-Glucose
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66229 |
DOPE-PEG-DOTA
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66230 |
DOPE-PEG-PEI
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66232 |
DOPE-PEG-Mannose
Featured
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DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability.
Moreover, DMPE-PEG displays highly tunable monolayer properties, enabling the modulation of liposome's charge, surface tension, and aggregation behavior by altering the length and density of the PEG chains. This tunability enhances the versatility of DMPE-PEG liposomes for various applications. |
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| DC66233 |
DOPE-PEG-Lactoferrin
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66234 |
DOPE-PEG-AC
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66235 |
DOPE-PEG-TCO
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66236 |
DOPE-PEG5000-Streptavidin
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66237 |
DOPE-PEG-cRGD
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66238 |
DOPE-PEG-RGD
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers. |
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| DC66239 |
DOPE-PEG-Transferrin
Featured
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DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers.
The transferrin receptor (TfR) is a transmembrane glycoprotein whose function is to mediate iron absorption through its interaction with transferrin. In normal cells, the expression level of the receptor is low, and the expression of the transferrin receptor in zhongliu cells (such as lung adenocarcinoma, chronic lymphocytic baixuebing and non-Hodgkin tumor) is significantly increased due to the increased demand for iron in rapidly growing cells [2-4].
At present, two transferrin receptors, TfR1 and TfR2, have been found, both of which are type II transmembrane glycoproteins that bind to transferrin and mediate iron absorption. TfR1 is expressed in many cells (such as red blood cells, hepatocytes, monocytes), and can change its conformation according to the change of environmental pH, and convert the results of conformational change into a change in the binding strength of transferrin.
TfR2 is mainly expressed in the liver, and its main function may be to regulate and maintain the homeostasis of iron ions in the body, while its role in transporting iron ions to rapidly dividing tissues is weak. Using the effective targeting function of transferrin receptor, the cross-linking of transferrin and drugs can improve the specific binding ability of drugs, but also improve the effect. |
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