DC5902 |
Emtricitabine
Featured
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Emtricitabine is a nucleoside analogue which inhibits the reverse nucleoside transcriptase enzyme. Structurally this antiviral agent is similar to Lamivudine. This agent is effective at targeting HIV and HBV viruses since these viruses replicate in a reve |
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DC4234 |
Etravirine |
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1). |
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DCAPI1011 |
Famciclovir (Famvir) |
Famciclovir (Famvir) |
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DC1057 |
Fidaxomicin (Dificid)
Featured
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Fidaxomicin, is an antibiotic that belongs to the class of macrocylic antibiotics. |
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DC7824 |
Fosfluconazole(INN) |
Fosfluconazole (INN) is a water-soluble phosphate prodrug of fluconazole |
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DC10307 |
Framycetin |
Framycetin (Fradiomycin B; Neomycin B) is an aminoglycoside antibiotic. It inhibits hammerhead ribozyme with a Ki of 13.5 μM. |
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DC8929 |
Garenoxacin |
Garenoxacin is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections. |
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DC8893 |
Garenoxacin Mesylate hydrate |
Garenoxacin mesylate hydrate is a novel oral des-fluoro(6) quinolone with potent antimicrobial activity, against common respiratory pathogens, including resistant strains. |
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DC2107 |
Gemcitabine HCl (Gemzar,LY188011)
Featured
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Gemcitabine Hydrochloride (Gemzar) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively,showed potent activity against COVID-19(SARS-COV-2) with EC50 MERS-COV(1.216), SARS-COV(4.9 |
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DC10161 |
Gepotidacin
Featured
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Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. |
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DC10818 |
ABT-493(Glecaprevir)
Featured
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Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM. |
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DC22629 |
GRL-0617
Featured
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GRL-0617 is a potent, noncovalent SARS-CoV papain-like protease (PLpro) inhibitor with IC50 of 0.6 uM, Ki of 0.49 uM. |
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DCAPI1505 |
Darunavir
Featured
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Darunavir(TMC114) is an HIV protease inhibitor,showed potent activity against COVID-19(SARS-COV-2) . |
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DC8983 |
Ibudilast
Featured
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Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma,ibudilast (MN-166) is tested to treat acute respiratory distress syndrome (ARDS) associated with Covid-19. |
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DC11494 |
INX-08189 |
INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. |
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DC7609 |
Isatoribine |
Isatoribine is a selective agonist of TLR7 |
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DCAPI1366 |
Itraconazole (Sporanox) |
Itraconazole (Sporanox) |
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DC8907 |
Lopinavir
Featured
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Lopinavir is a potent HIV protease inhibitor with Ki of 1.3 pM,showed potent activity against COVID-19(SARS-COV-2). |
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DC10258 |
Mebendazole |
Mebendazole is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking g |
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DC11419 |
Merimepodib
Featured
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Merimepodib(VX-497) is a novel noncompetitive inhibitor of IMPDH (Inosine monophosphate dehydrogenase). |
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DC8928 |
Minocycline hydrochloride
Featured
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Minocycline is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects. |
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DC12255 |
MLN-4760
Featured
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MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM). |
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DC4226 |
Moxifloxacin hydrochloride
Featured
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Moxifloxacin(Avelox, Avalox) is a fourth generation synthetic fluoroquinolone antibacterial agent. |
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DC11273 |
Murepavadin (POL7080)
Featured
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Murepavadin is a novel class of highly specific outer membrane protein targeting antibiotic to treat resistant Pseudomonas infections. |
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DC9619 |
Nafamostat (mesylate)
Featured
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Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant,showed highly potent activity against COVID-19(SARS-COV-2).
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DC9476 |
NBD-556
Featured
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NBD-556 is small molecule mimetic of CD4, NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.
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DC9477 |
NBD-557 |
NBD-557 is a potentially HIV-1 inhibitor.
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DC10355 |
Nelfinavir
Featured
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Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. |
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DC9474 |
Nelfinavir (Mesylate) |
Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. |
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DC9019 |
Nevirapine |
Nevirapine is a potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of HIV-1 infection and AIDS. |
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