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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC3474 Mrgx1-activator-1 Activator of MrgX1 receptor signaling
DCC3475 Mri-1891 Novel peripheral CB1R antagonist, being highly biased toward inhibiting CB1R-induced β-arrestin-2 (βArr2) recruitment over G-protein activation
DCC3476 Mrl-248 Novel potent and selective RORγT inhibitor, showing no appreciable activity against a panel of related nuclear hormone receptors
DCC3477 Mrl-299 Novel potent RORγT inhibitor
DCC3478 Mrl-367 Novel potent and selective RORγT inhibitor, showing no appreciable activity against a panel of related nuclear hormone receptors
DCC3479 Mrl-770 Novel selective and reproducible inhibitor of DNA synthesis in E. coli JL553
DCC3480 Mrs2220 Selective enhancer of the ATP effects at fast desensitizing P2X (P2X1 and P2X3) receptors
DCC3481 mrs2690 Potent P2Y14 receptor agonist
DCC3482 mrs2693 Trisodium Selective P2Y6 agonist
DCC3483 mrs2768 Selective P2Y2 agonist
DCC3484 mrs2957 Potent P2Y6 agonist
DCC3485 Mrs2964 Potent and selective P2Y6 receptor agonist
DCC3486 Mrs4598 Novel highly potent human CD73 inhibitor (K i = 0.673 nM)
DCC3487 Mrs4608 Novel potent antagonist of P2Y 14 receptor (P2Y 14 R) (IC 50 ~20 nM at hP2Y 14 R/mP2Y 14 R)
DCC3488 Mrs4654 Novel potent P2Y14 Receptor Antagonist (IC 50 , 15 nM)
DCC3489 Mrs7396 Bitopic fluorescent antagonist of the A2A adenosine receptor
DCC3490 Mrs7469 Novel highly selective A1 adenosine receptor (A1AR) agonist
DCC3491 Mrs7591 Novel Partial Agonist of Human and Mouse A3 Adenosine Receptors (Ki = 10.9/17.8 nM, at human/mouse A3AR)
DCC3492 Mrs7799 Novel highly potent A3 adenosine receptor (A3AR) antagonist with Kd values (nM): 0.55 (human), 3.74 (mouse), and 2.80 (rat)
DCC3493 Mrt-68601 Hydrochloride Potent inhibitor of TANK-binding kinase-1 (TBK1)/IKKepislon kinases
DCC3494 Mrt-92 Hydrochloride Novel inhibitor of Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor
DCC3495 Mrz-8676 Novel, selective, orally bioavailable, negative allosteric modulator of subtype 5 metabotropic glutamate receptors (mGluR5)
DCC3496 ms0017509 Inhibitor of DNA damage repair
DCC3497 ms0019266 Novel inhibitor of DNA damage repair
DCC3498 Ms2126 Novel inhibitor of Human p53 and CREB Binding Protein (CREBBP) interaction
DCC3499 Ms2177 Novel potent and selective SETD8 inhibitor
DCC3500 Ms2i6a Mitochondrial tRNA-specific modification, regulating efficient mitochondrial translation and energy metabolism in mammals
DCC3501 Msc2524070 Novel potent tankyrase (TNKS) inhibitor (EC 50 : 2 nM)
DCC3502 Msc-4381 Novel inhibitor of SLC16A3
DCC3503 Msd-496486311 Novel potent and selective PI3Kδ inhibitor

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