Home > Products > Novel inhibitors
Cat. No. Product name CAS No.
DCC1759 dgat2 Inhibitor 122

Selective inhibitor of diacylglycerol acyltransferase 2 (DGAT2)

620931-38-6
DCC1760 Dg-c8-phip

The major adduct formed by the food-borne carcinogen, PhIP with DNA

142784-25-6
DCC1761 Dgj-pfpht

Novel human α-galactosidase A ligand, capable of stabilizing α-Gal A and restoring trafficking

1609458-32-3
DCC1762 Dgts(16:0/16:0)

Abundant lipid in the membranes of many algae, lower plants, and fungi, showing an inverse concentration relationship with phosphatidylcholine, being capable of replacing phosphatidylcholine

1607456-57-4
DCC1763 Dgy-08-097

Novel HCV NS3 degrader, reducing susceptibility to resistance mutations, potently inhibiting HCV in a cellular infection model, exhibiting the most potent degradation (DC50 of 50nM at 4h) of HCV NS3,

DCC1764 Dh20931

Novel growth inhibitor of both triple-positive and triple-negative human breast cancer cell lines

DCC1765 Dha-37

Novel inducer of autophagic cell death through upregulation of HMGB1 in A549 cells

DCC1766 Dhpcc-9

Novel Pim kinase inhibitor

1192248-37-5
DCC1767 Dhpm-93

The most potent inhibitor of sodium iodide symporter (NIS) reported to date

1430815-67-0
DCC1768 Di-1859

Novel potent, selective and covalent inhibitor of DCN1, selectively inhibiting neddylation of cullin 3 in cells

DCC1769 Diabzi Sting Agonist

Novel STING agonist with enhanced binding to STING and cellular function, displaying strong anti-tumour activity

DCC1770 Diabzi Sting Agonist-3

Novel potent and selective STING agonist, activating secretion of IFNβ, IL-6, TNF, and KC/GROα, exhibiting durable anti-tumour effects

2138498-18-5
DCC1771 Diafluo

Novel probe for protein S-sulfinylation from cells

DCC1772 Dianicline

Selective alpha4beta2 nAChR partial agonist for the treatment of nicotine dependence to assist in smoking cessation

292634-27-6
DCC1773 Diazaborine

Novel Inhibitor of the AAA-ATPase Drg1, blocking ribosome biogenesis

22959-81-5
DCC1774 Diazoline

Histamine H1-receptor antagonist

6153-33-9
DCC1775 Dibromo-morin

Morin derivative, enhancing neural glyoxalase pathway (GP) activity and preventing methylglyoxal-mediated oxidative stress (OS) in an AD model

DCC1776 Diclofenac Acyl Glucuronide

Major biliary metabolite of Diclofenac, a nonsteroidal antiinflammatory drug and COX inhibitor

64118-81-6
DCC1777 Diclofenac Potassium

Non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions

15307-81-0
DCC1778 Diclosulam

Selective herbicide for the control of dicot weeds

145701-21-9
DCC1779 Did Perchlorate Featured

Lipophilic fluorescent reagent, labeling membranes and other hydrophobic structures

127274-91-3
DCC1780 Didehydro-cortistatin A

Natural Tat inhibitor, blocking HIV-1 transcription by specifically targeting the viral transactivator, Tat

1032315-06-2
DCC1781 Dids Sodium Salt

Inhibitor of DTDST inhibitor, a novel intestinal epigallocatechin gallate (EGCg) transporter

67483-13-0
DCC1782 Diethyl Bipy55'dc

Novel inhibitor of CP4H activity in cultured cells at concentrations that do not cause iron deficiency

1762-46-5
DCC1783 Diethyl Pyimdc

Novel inhibitor of CP4H activity in cultured cells at concentrations that do not cause iron deficiency

1821370-64-2
DCC1784 Diethylcarbamazine Citrate

Muscle relaxant, causing general central nervous system depression, relieving pain caused by strains, sprains, and other musculoskeletal conditions

1642-54-2
DCC1785 Difenidol

Antiemetic agent used in the treatment of vomiting and vertigo

972-02-1
DCC1786 Difeterol

Agonist of the androgen receptor (AR); #333333; font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans:

14587-50-9
DCC1787 Diflorasone

Corticosteroid Hormone Receptor Agonist

2557-49-5
DCC1788 Dihydralazine

Novel dose-dependent inhibitor of the SARS-CoV-2 Mac1 Macrodomain

484-23-1
DCC1789 Dihydrexidine Hydrochloride

D1-like full agonist with similar affinity for D1 and D5, and roughly 10-fold selectivity over D2-like receptors

137417-08-4
DCC1790 dihydro-beta-erythroidine Hydrobromide

Competitive nicotinic receptor antagonist

29734-68-7
DCC1791 Dihydrocyclosporin A

Closely related co-metabolite of cyclosporin A

59865-15-5
DCC1792 Dihydromotuporamine C Trihydrochloride

Unique antimigration and antiangiogenic agent

855997-15-8
DCC1793 Diic16tac

Novel lipid-based, high-density, environmentally sensitive (HIDE) probe

DCC1794 Diic16'tco

Novel lipid-based, high-density, environmentally sensitive (HIDE) probe

DCC1795 Dilazep

Vasodilator for the treatment of cardiopathy and renal disorders, acting as an adenosine reuptake inhibitor.

35898-87-4
DCC1796 Dimenthyl (1s,2s)-cyclopropane-1,2-dicarboxylate

Building Block

96149-00-7
DCC1797 Dimenthyl Succinate

Building Block

34212-59-4
DCC1798 dimethacrine

Novel inhibitor of AMA1-RON2 interaction, blocking merozoite invasion from schizont-infected RBCs; Antidepressant; Acetylcholinesterase inhibitor

4757-55-5
DCC1799 Dimethothiazine

Serotonin antagonist and histamine antagonist

7456-24-8
DCC1800 Dimethoxy-etomidate

Novel analog of etomidate, potently inhibiting 11-beta-hydroxylase without GABAA receptor positive modulatory and sedative-hypnotic activities

DCC1801 Diminazene

Anti-infective agent against certain protozoa such as Babesia, Trypanosoma, Cytauxzoon, and certain bacteria including Brucella and Streptococcus

536-71-0
DCC1802 Dimiq Hydrochloride

Inhibitor of Topoisomerase>DNA topoisomerase II; very potent cytotoxic antitumor agent

1011460-73-3
DCC1803 Dinalbuphine Sebacate

Long-lasting prodrug of nalbuphine, acting as a moderate-efficacy partial agonist or antagonist of the μ-opioid receptor and as a high-efficacy partial agonist of the κ-opioid receptor

311768-81-7
DCC1804 Dinapsoline

Natural full D1 dopamine receptor agonist

458563-40-1
DCC1805 Dipicrylamine Sodium Salt

Potent antagonist of GABA A receptors that contain alpha1 and beta2 subunits

13474-21-0
DCC1806 Dipquo

Novel activator of the bone marker alkaline phosphatase (ALP), markedly promoting osteoblast differentiation, including expression of Runx2, Osterix, and Osteocalcin, mediating osteogenesis through activation of p38-β

1269365-82-3
DCC1807 Dipraglurant

Novel negative allosteric modulator of the mGlu5 receptor

872363-17-2
DCC1808 Displurigen

Inhibitor of ATPase activity of HSP70

96156-26-2
DCC1809 Distamycin A Hydrochloride

Antibiotic, specifically inhibiting the initiation of RNA synthesis, binding isohelically to the minor groove of B-DNA at A/T rich sites

6576-51-8
DCC1810 Distigmine Dibromide

Parasympathomimetic with longer duration of action

15876-67-2
DCC1811 Djt06001

Novel selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding

1628182-40-0
DCC1812 Dk-1-150

Novel inducer of apoptotic cell death in TNBC cell lines without causing cytotoxicity in the normal mammary epithelial cell line

DCC1813 Dk-1-166

Novel inducer of apoptotic cell death in TNBC cell lines without causing cytotoxicity in the normal mammary epithelial cell line

2204279-20-7
DCC1814 Dk-139

Inhibitor of NF-kappaB-mediated GROalpha expression, suppressing the TNFalpha-induced invasive capability of MDA-MB-231 human breast cancer cells

1426059-23-5
DCC1815 Dk-1-49

Novel autophagonizer, inducing autophagic cell death in apoptosis-defective cell line

853136-76-2
DCC1816 Dl0410

Novel acetylcholinesterase inhibitor, promoting synaptic function and neuronal survival, ameliorating cognitive deficits in SAMP8 mice via improved mitochondrial dynamics and increased activity of the NMDAR-CREB-BDNF pathway

DCC1817 D-lana-14

Novel potent anti-MRSA agent, disrupting biofilms with no resistance development, sensitizing rifampicin and tetracycline against multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa

DCC1818 Dlc27-14

Specific protein disorder catalyzer of HIV-1 Nef

1360869-92-6
DCC1819 Dl-threo-dihydrosphingosine

Competitive inhibitor of both SPHK1 and SPHK2

2304-75-8
DCC1820 D-luciferin Phosphate Sodium Salt

Ultrasensitive bioluminogenic enzyme substrate

145613-12-3
DCC1821 D-lys(z)-pro-arg-pna

Chromogenic peptide substrate, being highly sensitive for the measurement of activated Protein C.

108963-69-5
DCC1822 Dma-cpptl

Prodrug of CPPTL, inducing apoptosis in a dose-dependent manner via the ROS/JNK pathway in acute myeloid leukemia

DCC1823 Dmako-20

Novel multi-target anticancer prodrug activated by the tumor specific CYP1B1 enzyme, potently inhibiting HCT-15, HCT-116 and K562 cells growth, showing moderate anti-proliferative activity towards MDA-MB-231, HepG2, PANC, Bel7402 and MGC803 cancer cells,

DCC1824 Dmako-5

Novel antineoplastic agent, exhibiting remarkable anticancer activity as well as excellent cellular selectivity

DCC1825 D-mannuronic Acid [6906-37-2]

Novel blocker of the TLR2 and TLR4 downstream signaling pathway, effectively inhibiting mRNA expression of MyD88 and p65, major subunit of nuclear factor-kappaB

6906-37-2
DCC1826 Dmb213

Novel non-nucleoside inhibitor of Zika viral RNA-dependent RNA polymerase (RdRp) enzymes

DCC1827 Dmcl1-2

Novel potent and selective PROTAC degrader of myeloid cell leukemia 1 (MCL1)

2351218-88-5
DCC1828 Dmnpe-caged Luciferin

Novel cell permeable caged Luciferin

223920-67-0
DCC1829 Dmocptl

Novel inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple negative breast cancer cells

DCC1830 Dmt-dalda

Potent and highly selective µ opioid agonist

DCC1831 Dmxb-a

Novel,orally active and selective alpha-7 nicotinic acetylcholine (nACh) receptor

148372-04-7
DCC1832 Dna Primase Inhibitor-1

Novel DNA primase inhibitor

874787-49-2
DCC1833 Dna Primase Inhibitor-13

Novel DNA primase inhibitor

261363-54-6
DCC1834 Dnac-1

Novel potentiator of β-lactam activity against Gram positive and Gram negative pathogens

1006021-30-2
DCC1835 Dndi-0690

Novel antitubercular and antiparasitic agent, possessing excellent in vitro activity against both L. donovani and Leishmania infantum as well as displaying a better safety profile

DCC1836 Do-601

Analeptic agent, stimulating central nervous system; Anti-barbiturate-overdose

100252-00-4
DCC1837 Dolastatin 10 Featured

Highly potent cytotoxic microtubule inhibitor

110417-88-4
DCC1838 Doot-2d

Selective MAO-B inhibitor

1522345-35-2
DCC1839 Dora 42

Dual orexin receptor antagonist (OX1R and OX2R antagonist or DORA)

1030377-48-0
DCC1840 Doramectin

Anthelmintic, for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle

117704-25-3
DCC1841 Dothiepin Hydrochloride

Tricyclic antidepressant (TCA), acting as a serotonin–norepinephrine reuptake inhibitor (SNRI) and also having other activities including antihistamine, antiadrenergic, antiserotonergic, anticholinergic, and sodium channel-blocking effects

25627-36-5
DCC1842 Dov51892

Agonist of GABAA receptors α15 subunits

864673-91-6
DCC1843 Dp-326

Novel antibacterial with activity against the Gram-negative bacteria associated with nosocomial infections

DCC1844 Dpa-154

Novel effective and selective inhibitor of E. coli topoisomerase I

DCC1845 Dpb163-ae

Novel 2-aminoethyl diphenylborinate (2-APB) analogue, inducing a profound activation of SOCE in DT40 cells, albeit at low concentrations (10 nM), blocking the melatonin-induced [Ca ] cyt increase and SOCE in P. falciparum.

DCC1846 Dpbx-l-dopa

Novel boron-containing dopa-derivative, acting as a bladder relaxant through non-catecholamine receptors

DCC1847 Dp-c-1

Novel Dual PROTAC for Simultaneous Degradation of EGFR and PARP

DCC1848 Dpf-p10

First Potent Small Molecule Ligand for MALAT1

DCC1849 Dpi-287

Novel highly selective agonist for the δ-opioid receptor, producing less convulsions than most drugs from this family and having antidepressant-like effects

DCC1850 Dpp7-in-5385

Novel inhibitor of dipeptidyl peptidase 7 (DPP7)

DCC1851 Dpp8/9-in-8j

Novel selective DPP8/9 inhibitor, blocking AML progression in vivo

DCC1852 Dppe Hydrochloride

Substrate of CYP3A and inhibitor of P-glycoprotein

92981-78-7
DCC1853 Dpre1-in-377790

Novel DprE1 inhibitor, killing M. tuberculosis

634167-64-9
DCC1854 D-propargylglycine

Click chemistry tool molecule in probing peptidoglycan (PG)

198774-27-5
DCC1855 Dp-v-4

Novel Dual PROTAC for Simultaneous Degradation of EGFR and PARP

DCC1856 Dri-c23041

Novel inhibitor of the interaction of hACE2 with the spike proteins of SARS-CoV-2 as well as SARS-CoV

DCC1857 Dri-c91005

Novel inhibitor of the interaction of hACE2 with the spike proteins of SARS-CoV-2 as well as SARS-CoV

DCC1858 Dropropizine

Oral non-opioid anti-tussive agent for treatment of cough

17692-31-8
DCC1859 Drostanolone Propionate

Inhibitor of the growth of estrogen receptor-presenting breast cancers

521-12-0
DCC1860 Ds08210767

Novel potent PTHR1 antagonist

2376334-75-5
DCC1861 Ds19161384

Novel selective PPARγ modulator, resulting in robust plasma glucose reductions with excellent DMPK profiles

DCC1862 Ds28120313

Novel potent orally active hepcidin production inhibitor

2146177-09-3
DCC1863 Ds37571084

Novel and orally bioavailable PTHR1 antagonist

DCC1864 Ds-3801b Hydrochloride

Novel non-macrolide GPR38 agonist

1369414-03-8
DCC1865 Ds42450411

Novel potent orally active hepcidin production inhibitor

DCC1866 Ds79932728

Novel Potent, Orally Available G9a/GLP Inhibitor for Treating β-Thalassemia and Sickle Cell Disease

DCC1867 Dsba Inhibitor F1

Pathogen motility inhibitor of EcDsbA

859833-20-8
DCC1868 Dshs00884

Non-toxic human papillomavirus E6 inhibitor

675104-49-1
DCC1869 Dsm-338

Novel Plasmodium falciparum Dihydroorotate Dehydrogenase (PfDHODH) Inhibitor (Pfalcip cells: 0.0018 μM)

DCC1870 Dsm502 Featured

Novel potent inhibitor of dihydroorotate dehydrogenase (DHODH)

2426616-55-7
DCC1871 Dsm705

Novel potent Dihydroorotate Dehydrogenase (DHODH) inhibitor

2653225-38-6
DCC1872 Dsr-98776

Novel selective mGlu5 receptor negative allosteric modulator (NAM) with potent antidepressant and antimanic activity

DCC1873 Ds-sg-44

Agonist of S1P receptors

DCC1874 Dt-061

Novel potent and orally active activator of PP2A

1809427-19-7
DCC1875 Dt2216nc

Negative control for DT2216

DCC1876 Dtagv-1

Potent and selective degrader of mutant FKBP12F36V fusion proteins

DCC1877 Du-34569 Maleate

Antiviral agent against influenza A, parainfluenza Sendai, coxsackie A21, and rhinovirus

34522-38-8
DCC1878 Duocarmycin A

Irreversible DNA minor groove binding alkylating agent, disrupting the nucleic acid architecture and leading to tumor cell death

118292-34-5
DCC1879 Dutomycin

Anthracycline antibiotic from Streptomyces

146663-67-4
DCC1880 Dv-7028

Selective 5-HT2A receptor antagonist

133364-63-3
DCC1881 Dv-7028 Hydrochloride

Potent and selective 5-HT 2A receptor antagonist

133364-62-2
DCC1882 Dw10075

Novel potent and highly selective inhibitor of VEGFR, exhibiting antitumor activities both in vitro and in vivo.

1804982-31-7
DCC1883 Dw-1350

Novel and potent leukotriene B(4) receptor antagonist

491577-61-8
DCC1884 Dwn-723-23

Novel Hsp70 agonist, showing no cellular toxicity and induced cellular stress response pathways

DCC1885 Dx2-hsp70 Inhibitor-1

Novel allosteric inhibitor of the tumor-promoting interaction between the oncogenic factor AIMP2-DX2 and HSP70

125105-17-1
DCC1886 Dx-52-1

Antitumor antibiotic

96251-59-1
DCC1887 Dy3002

Novel Selective and Potent EGFR Inhibitor, Overcoming T790M-Mediated Resistance in Non-Small Cell Lung Cancer

2020015-37-4
DCC1888 Dy428174

Novel potent Inhibitor of PI3Kalpha

1202041-71-1
DCC1889 E09241

Novel OPG/RANKL upregulator, increasing OPG expression without affecting RANKL expression, promoting osteoblast differentiation while inhibiting osteoclast differentiation, regulating OPG expression through canonical Wnt/β-catenin signaling

1043110-13-9
DCC1890 e2012-bpyne

γ-Secretase modulator (GSM) photoaffinity probe, revealing distinct allosteric binding sites on presenilin

1430800-80-8
DCC1891 E235-1756

Potent Activator of P53-Independent Cellular Senescence

891894-69-2
DCC1892 E3-ligase Degrader 10

Novel XIAP BIR2 domain-binding degrader of E3 ubiquitin ligases

DCC1893 E-5842 Citrate

Sigma1 receptor ligand and potential atypical antipsychotic

220120-14-9
DCC1894 Ea-b3a

Novel degrader of GST-α and GST-α-EGFP fusion proteins as well as endogenous GST-π in cells and lysates

DCC1895 Ebi-13a

Highly potent and selective activator of isozymes CA-VA and CA-VII

147596-31-4
DCC1896 Ebmi-13b

Highly potent and selective activator of isozymes CA-VA and CA-VII

21202-53-9
DCC1897 Ebopiprant

Novel Oral and Selective Prostaglandin F 2α (PGF 2α ) Receptor Antagonist

2005486-31-5
DCC1898 Ebov-in-c31

Novel PP1-targeting Ebola Virus (EBOV) inhibitor with improved pharmacological properties

752216-12-9
DCC1899 Ebselen Oxide

Novel dose-dependent inhibitor of HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9, inhibiting Pseudomonas aeruginosa alginate synthesis

104473-83-8
DCC1900 Ebv Activator C60

Novel EBV activator, well-performing EBV lytic cycle inducer

1031658-01-1
DCC1901 Ecdsbb-in-12

Novel potent specific inhibitor of EcDsbB, targeting disulfide bond forming enzyme

112749-52-7
DCC1902 Ecdsbb-in-9

Novel specific inhibitor of EcDsbB, targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria

41933-33-9
DCC1903 Echinoside A

Novel marine-derived anticancer saponin, targeting topoisomerase2alpha by unique interference with its DNA binding and catalytic cycle

75410-53-6
DCC1904 Ecraprost

Lipo-pro-prostaglandin E1, preventing hearing disturbance and equilibrium dysfunction due to inner ear microcirculatory disorders

136892-64-3
DCC1905 Edoxaban Isomer

An impurity of Edoxaban, a novel inhibitor of factor Xa

1255529-24-8
DCC1906 Eef2k-in-21i

Novel eEF2K inhibitor, inducing significant apoptosis through classical apoptotic pathways

DCC1907 Efatutazone

Potent agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma) with potential antineoplastic activity

223132-37-4
DCC1908 Efonidipine

Calcium channel blocker, blocking both T-type and L-type calcium channels

111011-63-3
DCC1909 Efrapeptin F

Natural alpha-aminobutyric acid-rich secondary metabolite of fungi, strongly inhibiting the BBMV V-ATPase, acting as a mitochondrial complex V inhibitor, showing antitumor activity in vivo

131353-66-7
DCC1910 Efrotomycin

Antibiotic, inhibiting bacterial protein synthesis

56592-32-6
DCC1911 Egfr T790m Inhibitor 6a

Novel third-generation EGFR tyrosine kinase inhibitor, targeting EGFR T790M mutation in advanced non-small cell lung cancer

DCC1912 Egfr-in-451

Novel EGFR inhibitor, attenuating Ang II-induced Kidney Fibrosis

220576-72-7
DCC1913 Egfr-in-542

Novel EGFR inhibitor, significantly reducing myocardial inflammation, fibrosis, apoptosis, and dysfunction, showing promises to the treatment on obesity-induced cardiac complications

1639040-81-5
DCC1914 Egfr-in-557

Novel EGFR inhibitor, attenuating Ang II-induced Kidney Fibrosis

1639040-91-7
DCC1915 Egis-11150

Potent inhibitor of adrenergic alpha1, alpha2c, 5-HT2a, 5HT7 receptors; Relatively selective blocker of adrenergic alpha2c over adrenergic alpha2a receptors.

494861-87-9
DCC1916 Egis-8332

Selective, non-competitive AMPA receptor antagonist, improving motor co-ordination

220725-87-1
DCC1917 Egonol

Antibacterial agent

530-22-3
DCC1918 Eh-201

Arginase Inhibitor, activating EPO-mediated mitochondrial function and haemoglobin expression, stimulating melanogenesis by MAP kinase activation and tyrosinase upregulation

55327-45-2
DCC1919 Ehi1471

Potent and bio-stable inhibitor of the chicken sEH (chxEH)

DCC1920 Ehi2119

Potent and bio-stable inhibitor of the chicken sEH (chxEH)

DCC1921 Ehi2225

Potent and bio-stable inhibitor of the chicken sEH (chxEH)

DCC1922 Eht5372

Novel Mirk kinase inhibitor, inhibiting DYRK1A-induced Tau phosphorylation at multiple AD-relevant sites, blocking the in vivo growth of pancreatic cancer cells

1425945-60-3
DCC1923 Eidd-1619

Novel water-soluble analog of progesterone

1659302-92-7
DCC1924 Eidd-1723

Novel water-soluble analog of progesterone, reducing cerebral edema and lesion size and improving functional recovery, decreasing glial fibrillary acidic protein expression immunoreactivity

1659302-89-2
DCC1925 Eif4a Inhibitor 28

Novel RNA-competitive, ATP-uncompetitive eIF4A Inhibitor, decreasing BJAB Burkitt lymphoma cell viability, engaging a novel pocket in the RNA groove of eIF4A and inhibiting unwinding activity by interfering with proper RNA binding and suppressing ATP hydr

DCC1926 Ejmch-6

Novel anti-bacterial agent, targeting the MmpL3 transporter in Mycobacterium abscessus

DCC1927 Ejr-866-75

Novel Cell-active Inhibitor of the Undrugged Oncogenic PTP4A3 Phosphatase

DCC1928 Ejr-866-81

Novel Cell-active Inhibitor of the Undrugged Oncogenic PTP4A3 Phosphatase

DCC1929 El-0052

Novel etomidate analogue, enhancing GABA A receptors currents with a concentration for 50% of maximal effect (EC 50 ) of 0.98 {plus minus} 0.02 μM, which was about three times more potent than etomidate (3.07 {plus minus} 1.67 μM), retaining the favorable

DCC1930 El-228

Novel inhibitor of Aurora B kinase

DCC1931 Ela23-32

Novel ligand of the apelin receptor (APJ), possessing high affinity for APJ (Ki 4.6 nM) and producing cardiorenal effects in vivo similar to those of ELA

DCC1932 elaidyl-sulfamide

Oleoylethanolamide-modelled PPAR

945009-57-4
DCC1933 Elnd006

Novel γ-secretase inhibitor

959997-22-9
DCC1934 Elovl1 Inhibitor 22

Novel highly potent, selective, and CNS-penetrant inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme

DCC1935 Elx-02

Eukaryotic Ribosomal Selective Glycoside (ERSG), inducing read-through of premature stop codons (PSCs) and resulting in translation of full-length protein

1375073-95-2
DCC1936 Em20-25

Novel BCL-2 inhibitor, neutralizing the antiapoptotic activity of overexpressed BCL-2 toward staurosporine and sensitizing BCL-2-expressing cells from leukemic patients to the killing effects of staurosporine, chlorambucil, and fludarabine

141266-44-6
DCC1937 em-800

High affinity ligand for estrogen receptor-

182167-03-9
DCC1938 Emac4001

Novel potent antitumor agent, inducing apoptosis in a panel of tumor cell lines

DCC1939 Emd-1204831

Novel potent and highly selective c-Met inhibitor

1362819-72-4
DCC1940 Emd57439

PDE 3 inhibitor

148714-88-9
DCC1941 Emd-66684

Non-peptide angiotensin II receptor antagonist

187683-79-0
DCC1942 Emdb-1

Novel peptide endomorphin (EM) degradation blocker

DCC1943 Emdb-2

Novel peptide endomorphin (EM) degradation blocker

DCC1944 Emdb-3

Novel peptide endomorphin (EM) degradation blocker

DCC1945 Emicerfont

Novel corticotropin-release factor 1 antagonist

786701-13-1
DCC1946 Emitefur

5-FU derivative, with various anticancer agents against human cancer xenografts

110690-43-2
DCC1947 Eml108

Novel PRMT inhibitor, preventing arginine methylation of cellular proteins, being essentially inactive against the lysine methyltransferase SET7/9

DCC1948 Eml981

Novel Potent and Selective Inhibitor of Protein Arginine Methyltransferase 4 (PRMT4)

DCC1949 Emoxypine Succinate

Antioxidant, inhibiting free radical oxidation of biomembrane lipids, modulating the activity of membrane-bound enzymes and the receptor complexes of the brain membranes

127464-43-1
DCC1950 En3356

Novel non-steroidal CYP17 inhibitor. reducing androgen synthesis for treatment of castration-resistant prostate cancer

1429329-63-4
DCC1951 Ena739155

Novel butyrylcholinesterase inhibitor against Alzheimer's disease

DCC1952 Encenicline

Novel Potentiator of α7 Receptor Signaling

550999-75-2
DCC1953 Endo-3-aminotropane Dihydrochloride

Useful pharmceutical building block

5424-16-8
DCC1954 Endochin

Antimalarial

354155-51-4
DCC1955 Endosidin1

Natural vesicle trafficking inhibitor

57672-91-0
DCC1956 Endosidin3

Specific inhibitor of trafficking pathways, disrupting recycling at the PM via interference with ROP6/RIC1 signalling

DCC1957 Endosidin4

Novel inhibitor of eukaryotic ARF-GEFs (ADP-ribosylation factor guanine nucleotide exchange factors)

DCC1959 Endosidin7

Specific inhibitor for plant callose deposition during cytokinesis without affectting endomembrane trafficking during interphase or cytoskeletal organization

329072-88-0
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