Cat. No. | Product name | CAS No. |
DC11054 |
RORγt inverse agonist 22
RORγt inverse agonist 22 is a potent, subtype selective RORγt inverse agonist with binding IC50 of 18 nM, displays >192-fold selectivity over RORα and RORβ. |
1644029-01-5 |
DC11202 |
RORγt inverse agonist 32
RORγt inverse agonist 32 is a potent, orally bioavailable inverse agonist of RORγt with IC50 of 9 nM in SPA binding assays. |
|
DC22834 |
Roseoflavin
Featured
Roseoflavin is a chemical analog of FMN and riboflavin that has antimicrobial activity. |
51093-55-1 |
DC5015 |
Rotigotine Hydrochloride
Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic α2B receptors. Rotigotine exhibits antiparkinsonian acitivity. |
125572-93-2 |
DC23834 |
Rottlerin
Featured
Rottlerin (Mallotoxin. |
82-08-6 |
DC11159 |
Roxyl-WL
Roxyl-WL is a highly potent and selective inhibitor of IDO1 with IC50 of 1 nM. |
667887-37-8 |
DC23836 |
Roy-Bz
Roy-Bz is the first small-molecule PKCδ-selective activator with EC50 of 58.5 nM, binds to the PKCδ-C1-domain. |
1246304-91-5 |
DC11292 |
RP-1859
RP-1859 is a selective stimulator of S1P1 and S1P5 (S1P1 IC50 = 0.20 nM; S1P5 IC50 = 170 nM) used for the treatment of autoimmunity disease. |
1307869-95-9 |
DC11293 |
RP-1865
RP-1865 is a selective stimulator of S1P1 and S1P5 used for the treatment of autoimmunity disease. |
1307869-93-7 |
DC21585 |
Brilaroxazine
Featured
RP-5063 (Brilaroxazine) is a multimodal dopamine and serotonin modulator with partial agonist activity at DA D2, D3, D4, 5-HT1A, and 5-HT2ARs, and antagonist activity at 5-HT2B, 5-HT6 and 5-HT7Rs. |
1239729-06-6 |
DC11671 |
RPL-554
RPL-554 (LS-193855, RPL554) is a potent, orally available, dual PDE3/PDE4 inhibitor with IC50 of 0.4 nM and 1479 nM, respectively. |
298680-25-8 |
DC20538 |
Rpn11 inhibitor 35
Rpn11 inhibitor 35 is a potent, small molecule inhibitor of the proteasome subunit Rpn11 with IC50 of 400 nM,100-fold selectivity over Csn5 and 10-fold selectivity over AMSH. |
2084868-04-0 |
DC8105 |
RPR-260243
RPR260243 was the first reported hERG channel activator. |
668463-35-2 |
DC22217 |
RRD-251
RRD-251 hydrochloride is a small molecule disruptor of Rb/Raf-1 interaction, potently and selectively disrupts the Rb/Raf-1 (IC50=77 nM) but not Rb/E2F, Rb/prohibitin, Rb/cyclin E, and Rb/HDAC binding. |
131916-62-6 |
DC23808 |
RRD-251 hydrochloride
RRD-251 hydrochloride is a small molecule disruptor of Rb/Raf-1 interaction, potently and selectively disrupts the Rb/Raf-1 (IC50=77 nM) but not Rb/E2F, Rb/prohibitin, Rb/cyclin E, and Rb/HDAC binding. |
72214-67-6 |
DC12250 |
RS 17053 hydrochloride (RS-17053)
RS 17053 hydrochloride is a potent and selective α1A adrenoceptor antagonist, with a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays. |
169505-93-5 |
DC20539 |
RSK2-IN-20
RSK2-IN-20 is a potent, selective, and durable inhibitpr of RSK2 with IC50 of 47 nM. |
1627136-55-3 |
DC12486 |
RSV inhibitor compound 1
RSV inhibitor compound 1 is a novel potent, orally bioavailable RSV fusion inhibitor with EC50 of 2 nM (RSV Long strain infected HEp-2 cells) without significant cytotoxicity (CC50>100 uM). |
1422496-79-4 |
DC23097 |
RSV604 R enantiomer
RSV604 R enantiomer is the R-enantiomer of RSV604, which is a potent respiratory syncytial virus (RSV) inhibitor targeting the nucleocapsid protein, is less active against RSV.. |
932108-20-8 |
DC10435 |
RSV604 racemate
RSV604 racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer. |
676128-62-4 |
DC12132 |
RSV-IN-1
RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC50 of 0.11 μM. |
861139-16-4 |
DC8198 |
RTA-408(Omaveloxolone)
Featured
RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 and inhibits the proinflammatory transcription factor NF-κB. |
1474034-05-3 |