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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC22888 β2AR-IN-15 An allosteric, small-molecule negative modulator for β2AR with Kd of 1.7 uM.
DC22827 DBCO-NHS ester An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.
DC21155 Myriocin An amino fatty acid antibiotic that is 10- to 100-fold more potent than cyclosporin A as an immunosuppressive agent of the immune response in vitro and in vivo.
DC24005 Apramycin An aminoglycoside antibiotic used in veterinary medicine..
DC22371 Rocuronium An aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia. .
DC22575 MLN-4924 hydrochloride An analog of adenosine 5’-monophosphate that potently and selectively inhibits NEDD8-activating enzyme (NAE) with IC50 of 4.7 nM.
DC20908 Beloranib hemioxalate An analog of the natural compound Fumagillin that functions as a highly potent methionine aminopeptidase 2 (MetAP2) inhibitor.
DC24054 Poloxime Featured An analog of thymoquinone that blocks pSer/pThr recognition by Plk1 Polo-box domain as a phosphate mimic..
DC22561 N-563 An analogue of deoxyspergualin that has immunostimulating activity, promotes resistance to Candida albicans infection in mice..
DC26076 D-Ala2, D-Leu5-Enkephalin Featured An angiotensin II analog that is an agonist of AT1 angiotensin receptor..
DC11788 Pyrvinium Iodide An anthelmintic effective for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity.
DC11787 Pyrvinium An anthelmintic effective for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity.
DC24144 Bithionol An anthelmintic that has antibacterial and anthelmintic properties along with algaecide activity.
DC24143 Bithionol sulfoxide An anthelmintic that has antibacterial and anthelmintic properties along with algaecide activity.
DC23230 Eltoprazine An antiaggressive agent that acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor..
DC23229 Eltoprazine hydrochloride An antiaggressive agent that acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor..
DC24146 Vancomycin An antibiotic used to treat a number of bacterial infections that acts by inhibiting proper cell wall synthesis..
DC24004 Norvancomycin hydrochloride An antibiotic used to treat a number of bacterial infections that acts by inhibiting proper cell wall synthesis..
DC24148 Penicillin G potassium An antibiotic used to treat a number of bacterial infections..
DC22927 Thymoquinone An anticancer phytochemical commonly found in black cumin.
DC24149 Dichlorophen An anticestodal agent, fungicide, germicide, and antimicrobial agent.
DC24147 Clotrimazole An antifungal agent that works by altering the permeability of the fungal cell wall.
DC22836 Cerulenin An antifungal antibiotic that inhibits fatty acid synthase (FASN), also blocks cellular proliferation of KRAS-associated lung cancer cells.
DC22350 Hexachlorophene An anti-infective, anti-bacterial agent.
DC20373 Epeleuton An anti-inflammation agent..
DC24172 Oxaceprol An anti-inflammatory agent used in the treatment of osteoarthritis.
DC23252 GNF-Pf-5660 An antimalarial candidate that demonstrates potent blood-stage and transmission-blocking activity, shows potent ABS activity (IC50 <25 nM) against drug-sensitive 3D7 and multidrug-resistant Dd2 parasites.
DC25077 Naphthoquine phosphate Featured Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine.
DC22497 MMAF-OMe Featured MMAF-Ome belongs to ADC, and inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively.
DC22483 Quinacrine dihydrochloride An antiprotozoal, antirheumatic and intrapleural sclerosing agent.

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