Cas No.: | 69-05-6 |
Chemical Name: | 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, hydrochloride (1:2) |
Synonyms: | Mepacrine dihydrochloride;SN-390 |
SMILES: | Cl.CCN(CCCC(NC1C2C=CC(=CC=2N=C2C=CC(=CC=12)OC)Cl)C)CC |
Formula: | C23H32Cl3N3O |
M.Wt: | 472.8787 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | An antiprotozoal, antirheumatic and intrapleural sclerosing agent; inhibits histamine N-methyltransferase (HNMT); also strongly induces p53 function, suppresses both basal and inducible activities of NF-kappaB in RCC and other types of cancer cells; promotes autophagic cell death and chemosensitivity in ovarian cancer and attenuates tumor growth.Prostate CancerPhase 2 Clinical |