| DC11180 |
Amgen 16 |
Amgen16 is a highly potent inhibitor of NF-κB inducing Kinase (NIK), example 294 in patent WO 2009158011 A1.. |
|
| DC8503 |
AMG-Tie2-1
Featured
|
AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC50 <1 nM). |
|
| DC9548 |
Amicarbazone |
Amicarbazone(BAY-MKH3586; BAY314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); herbicide with a broad spectrum of weed control.
|
|
| DC11324 |
Aminopeptidase N Inhibitor |
Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). |
|
| DC11193 |
Aminopyridine 2 |
Aminopyridine 2 (MPO inhibitor AP-2) is a novel potent, selective, orally available inhibitor of Myeloperoxidase (MPO), inhibits MPO peroxidase activity in vitro and in human plasma with IC50 of 0.16 and 1.9 uM, respectively. |
|
| DC20206 |
Amitriptyline；MK-230, N-750, Ro41575 |
Amitriptyline is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. |
|
| DC20188 |
Amodiaquine |
Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria. |
|
| DC8923 |
AS-1413(Amonafide) |
Amonafide(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. |
|
| DC9406 |
Ampiroxicam |
Ampiroxicam(CP65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
|
|
| DC11130 |
AMPK activator 991 |
AMPK activator 991 is an allosteric AMPK activator, activates non-phosphorylated Thr172 AMPK in vitro binds to α1β1γ1 and α2β1γ1 with Kd of 0.13 and 0.17 uM, respectively.. |
|
| DC11129 |
AMPK activator SC4 |
AMPK activator SC4 is a potent, specific activator of α2β2-AMPK complexes with EC50 of 17.2 and 82.1 nM for α2β2γ1 and α2β2γ3, the predominant AMPK isoform complexes in human skeletal muscle. |
|
| DC23111 |
Ampkinone |
Ampkinone is a novel small molecule activator of AMPK, stimulates the phosphorylation of AMPK via indirect activation of AMPK in various cell lines (2.7-fold at 10 uM). |
|
| DC11076 |
Ampreloxetine |
Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively. |
|
| DC7058 |
Amprenavir
Featured
|
Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection. |
|
| DC23625 |
AMR-2 |
AMR-2 is a highly potent, orally active, triple reuptake inhibitor of SERT, NET, and DAT with IC50 of 3.0, 3.1, and 8.3 nM, respectively. |
|
| DC7002 |
Amrubicin(SM-5887) |
Amrubicin(SM-5887) is a novel anthracycline derivative for treatment of bladder carcinoma. |
|
| DC9634 |
Amsacrine |
Amsacrine (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells. |
|
| DC7510 |
TAC-101 |
amsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity. TAC-101 inhibits retinoblastoma-gene product (RB) phosphorylation and increases the presence of 2 cyclin-dependent kinase (CDK) inhibitors, resulting in cell cycle arrest. This agent also causes a cytotoxic decline in cyclin A and thymidylate synthase expression. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).For the detailed information of TAC-101, the solubility of TAC-101 in water, the solubility of TAC-101 in DMSO, the solubility of TAC-101 in PBS buffer, the animal experiment (test) of TAC-101, the cell expriment (test) of TAC-101, the in vivo, in vitro and clinical trial test of TAC-101, the EC50, IC50,and Affinity of TAC-101, Please contact DC Chemicals.. |
|
| DC20088 |
Amuvatinib hydrochloride (MP470 hydrochloride; HPK 56 hydrochloride) |
Amuvatinib hydrochloride (MP470 hydrochloride) is a multi-targeted receptor tyrosine kinases inhibitor, which inhibits c-Kit (D816V), c-Kit (D816H), c-Kit (V560G), c-Kit (V654A), PDGFRα (D842V), and PDGFRα (V561D) with IC50s of 950 nM, 10 nM, 34 nM, 127 n |
|
| DC21995 |
AMXT-1501 |
AMXT-1501 (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination of with DFMO. |
|
| DC21996 |
AMXT-1501 tetrahydrochloride |
AMXT-1501 tetrahydrochloride (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination with DFMO. |
|
| DC23109 |
AMZ30 |
AMZ30 is a potent, selective, covalent inhibitor of the serine hydrolase protein phosphatase methylesterase-1 (PME-1) with IC50 of 0.6 uM, >100-fold selectivity over other SHs. |
|
| DC25088 |
Rivastigmine
Featured
|
An acetylcholinesterase (AChE) inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. |
|
| DC11651 |
HLY-78
Featured
|
HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction[1]. |
|
| DC22762 |
Norendoxifen |
An active metabolite of the selective estrogen receptor modulator (SERM) tamoxifen. |
|
| DC23227 |
N6-Cyclohexyladenosine
Featured
|
An adenosine A1 receptor agonist (EC50= 8.2 nM).. |
|
| DC24153 |
Cysteamine hydrochloride |
An agent for the treatment of nephropathic cystinosis and an antioxidant. |
|
| DC23931 |
Hydrastine |
An alkaloid of Hydrastis canadensis used in many dietary supplements intended to enhance the immune system. |
|
| DC11657 |
PPT(Propyl pyrazole triol )
Featured
|
Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%). |
|
| DC21630 |
SCF-I2 |
An allosteric, sepecific inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase with IC50 of 6.2 uM in FP assyas. |
|
