| DC20735 |
AZD 8329 |
AZD8329 is a potent, selective 11β-HSD1 inhibitor with IC50 of 9 nM, displays excellent selectivity versus relatedd 11β-HSD2, 17β-HSD1 and 17β-HSD3 (IC50>30 uM). |
|
| DC7077 |
AZD8330(ARRY-424704; ARRY-704)
Featured
|
AZD8330(ARRY-424704; ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. |
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| DC23437 |
AZD-8529
Featured
|
AZD8529 is a novel potent, selective mGluR2 positive allosteric modulator with EC50 of 195 nM, does not produce any positive allosteric modulator responses for mGluR1 and 3-8 subtypes. |
|
| DC23408 |
AZD-8529 mesylate
Featured
|
AZD8529 is a novel potent, selective mGluR2 positive allosteric modulator with EC50 of 195 nM, does not produce any positive allosteric modulator responses for mGluR1 and 3-8 subtypes. |
|
| DC10202 |
AZD8797
Featured
|
AZD8797 is an allosteric non-competitive modulator of the human CX3CR1 receptor; antagonizes CX3CL1 with IC50 values of 6 and 300 nM in B-lymphocyte cell line and human whole blood, respectively. |
|
| DC10425 |
AZD9056 hydrochloride |
AZD9056 is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases. |
|
| DC10112 |
AZD9362 |
AZD-9362 is dual IGF-IR/InsR inhibitor. |
|
| DC11541 |
AZD-9567 |
AZD-9567 (AZD9567) is a potent, selective, non-steroidal and orally available selective glucocorticoid receptor modulator (SGRM) for treatment of rheumatoid arthritis.. |
|
| DC11542 |
AZD-9567 monohydrate |
AZD-9567 (AZD9567) is a potent, selective, non-steroidal and orally available selective glucocorticoid receptor modulator (SGRM) for treatment of rheumatoid arthritis.. |
|
| DC20737 |
AZD-9819 |
AZD-9819 is an inhibitor of human neutrophil elastase for potential treatment of chronic obstructive pulmonary disease.. |
|
| DC11032 |
AZD9977
Featured
|
AZD9977 is a first-in-class, potent, selective, mineralocorticoid receptor (MR) modulator with IC50 of 0.37. 0.08 and 0.08 uM for human, mouse and rat MR, respectively. |
|
| DC10245 |
Azelaic acid |
Azelaic acid is an organic compound produced by the ozonolysis of oleic acid and possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity. |
|
| DC20156 |
Azetidine-2-carboxylic acid
Featured
|
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent. |
|
| DC4210 |
Azilsartan kamedoxomil
Featured
|
Azilsartan medoxomil is an angiotensin II receptor antagonist indicated for the treatment of mild to moderate essential hypertension. |
|
| DC9596 |
Azimilide (Dihydrochloride) |
Azimilide 2Hcl(NE-10064 2Hcl) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.
|
|
| DC4141 |
Azocosterol 2HCL |
Azocosterol is a potential avian reproductive inhibitor. |
|
| DC10992 |
Azosemide |
Azosemide (Azosemidum) is a potent Na-K-Cl Cotransporter NKCC1 with IC50 of 0.246 and 0.197 uM for hNKCC1A and NKCC1B, being about 4-times more potent than bumetanide. |
|
| DC22953 |
AZSMO-23 |
AZSMO-23 (AZSMO 23, AZSMO23) is a potent hERG potassium channel (Kv11.1) activator that activates WT hERG pre-pulse and tail current with EC50 of 28.6 and 11.2 μM respectively. |
|
| DC21570 |
Azvudine
Featured
|
Azvudine (RO 0622) is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 24 nM; inhibits RNA synthesis by HCV polymerases from either HCV genotypes 1a and 1b or containing S96T or S282T point mutations (IC50=10-100 nM). |
|
| DC23756 |
Aβ polymerization stimulator O4 |
Aβ polymerization stimulator O4 is an orcein-related small molecule can drive polymerization of amyloid-β (Aβ). |
|
| DC12114 |
B I09 |
B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM. |
|
| DC22010 |
B591 |
B591 (B-591) is a potent, specific pan-PI3K inhibitor with IC50 of 1.3/0.36/1.1/1.58 uM for PI3Kα/β/γ/δ, respectively. |
|
| DC22011 |
BAA473 |
BAA473 (BAA-473) is a bile acid analogue that functions as the first small molecule activator of the Pyrin inflammasome, induces secretion of IL18 in LPS-primed PBMCs. |
|
| DC20063 |
BACE1-IN-2 |
BACE1-IN-2 is a 1,4-Oxazine β-Secretase 1 (BACE1) inhibitor with an IC50 of 22 nM. |
|
| DC8858 |
Bafilomycin A1(Baf-A1)
Featured
|
Bafilomycin A1 is a vacuolar H+-ATPase inhibitor with IC50 of 0.44 nM. |
|
| DC20740 |
BAL30072 |
BAL30072 is a monocyclic beta-lactam antibiotic that shows potent activity against MDR Pseudomonas aeruginosa and Acinetobacter sp. Isolates with MIC90 of 8 and 4 ug/ml. |
|
| DC10994 |
Balamapimod |
Balamapimod (MKI-833) is an orally active, reversible Ras/Raf/MEK inhibitor developed for antineoplastic potential.. |
|
| DC7541 |
Balapiravir |
Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). |
|
| DC11516 |
Balovaptan
Featured
|
Balovaptan (RG7314, RG-7314) is a potent, selective vasopressin-1 receptor antagonist.. |
|
| DC11057 |
Baloxavir acid
Featured
|
Baloxavir acid (S-033447) is an anti-influenza compound that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses. |
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