Cat. No. | Product name | CAS No. |
DC46941 |
Cl-4AS-1
Cl-4AS-1, a potent steroidal androgen receptor (AR) agonist (IC50 = 12 nM), is also an inhibitor of 5α-reductase types I and II (IC50 = 6 and 10 nM, respectively). |
188589-66-4 |
DC46951 |
Dazucorilant
Dazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor (GR) modulator with a Ki value <1 nM in vitro. Dazucorilant can be used for the research of neurological disorders. |
1496508-34-9 |
DC46967 |
Baxdrostat
Featured
Baxdrostat is a aldosterone synthase inhibitor. |
1428652-17-8 |
DC46968 |
Ocedurenone
Ocedurenone is a corticosteroid receptor antagonist. Ocedurenone can be used for the research of kidney disease (WO2018054357, compound I). |
1359969-24-6 |
DC46974 |
Glutaurine
Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia. |
56488-60-9 |
DC46975 |
VT103
VT103, an analog of VT101, is an orally active and selective TEAD1 protein palmitoylation inhibitor. VT103 inhibits YAP/TAZ-TEAD promoted gene transcription, blocks TEAD auto-palmitoylation, and disrupts interaction between YAP/TAZ and TEAD. VT103 can be used for the research of cancer. |
2290608-13-6 |
DC47001 |
Rezvilutamide
Rezvilutamide (SHR3680) is an androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer. |
1572045-62-5 |
DC47003 |
Bevurogant
Featured
Bevurogant is a retinoid-related orphan receptor-gamma t (RORγt) antagonist. Bevurogant can be used for the research of chronic inflammatory diseases. |
1817773-66-2 |
DC47081 |
Zavacorilant
Zavacorilant is capable of modulating glucocorticoid receptor (GR). |
1781245-13-3 |
DC47094 |
MK-3984
MK-3984 is a selective androgen receptor modulator (SARM). MK-3984 can be used for the research of muscle wasting associated with cancer. |
871325-55-2 |
DC47139 |
ATRA-biotin
ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue. |
2226143-93-5 |
DC47176 |
GW 590735
GW 590735 is a potent and selective PPARα agonist. GW 590735 showsEC50=4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW 590735 can be used for the research of dyslipidemia. |
343321-96-0 |
DC47207 |
Dagrocorat hydrochloride
Dagrocorat (PF-00251802) hydrochloride is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor. Dagrocorat hydrochloride is also a time-dependent reversible inhibitor of CYP3A (IC50=1.3 μM in human liver microsomes) and CYP2D6 (Ki=0.57 μM in human liver microsomes). Dagrocorat hydrochloride can be used for the research of rheumatoid arthritis. |
1044535-61-6 |
DC47238 |
Rintodestrant
Rintodestrant (G1T48) is an orally active, non-steroidal and selective estrogen receptor degrader. Rintodestrant (G1T48) is also a CDK4/6 inhibitor. |
2088518-51-6 |
DC47345 |
RORγt inverse agonist 23
RORγt inverse agonist 23 is a potent, selective, and orally available novel retinoic acid receptor-related orphan receptor γt inverse agonist. |
2230779-18-5 |
DC47346 |
RORγ agonist 1
RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC50 = 21 nM) with antitumor activity. |
2260631-91-0 |
DC47588 |
Keap1-Nrf2-IN-3
Keap1-Nrf2-IN-3 is a KEAP1:NRF2 protein−protein interaction inhibitor, and with a Kd value of 2.5 nM for KEAP1 protein. |
2095066-47-8 |
DC47623 |
Dimethyl-bisphenol A
Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α inhibitor. Dimethyl-bisphenol A can decrease Vegfa mRNA expression. |
1568-83-8 |
DC47633 |
Glucocorticoids receptor agonist 2
Glucocorticoids receptor agonist 2 is a potent anti-inflammatory, arylpyrazole-based glucocorticoid receptor agonist that does not impair insulin secretion. |
614761-20-5 |
DC47634 |
Glucocorticoids receptor agonist 1
Glucocorticoids receptor agonist 1 is a potent anti-inflammatory, arylpyrazole-based glucocorticoid receptor agonist that does not impair insulin secretion. |
694526-54-0 |
DC47660 |
eIF4A3-IN-4
eIF4A3-IN-4 is a novel eIF4A inhibitor with an IC50 value of 8.6 μM. |
|
DC47661 |
Estrone sulfate sodium
Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). strone sulfate can be used for the research of breast cancer. |
438-67-5 |