Cat. No. | Product name | CAS No. |
DC70967 |
Eptazocine
Eptazocine (Sedapain) is a κ-opioid receptor agonist and μ-opioid receptor antagonist. Eptazocine has the effect of relieving pain. |
72522-13-5 |
DC71347 |
BW373U86
BW373U86 (SNC86) is a δ-opioid receptor agonist with an IC50 of 1.49 nM. BW373U86 shows antidepressant-like effects. |
155836-50-3 |
DC71348 |
SNC162
SNC162 is a delta-opioid receptor agonist with an IC50 of 0.94 nM. SNC162 has antidepressant-like effects and produces a selective enhancement of the antinociceptive effects of fentanyl in rhesus monkeys. |
178803-51-5 |
DC71526 |
[Leu5]Enkephalin
[Leu5]Enkephalin a five amino acid endogenous peptide that acts as an agonist at opioid receptors. |
58822-25-6 |
DC72343 |
ZP 120C
ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia. |
383123-18-0 |
DC72344 |
NAQ
NAQ is a potent and selective μ opioid receptor partial agonist, with a Ki of 0.55 nM. NAQ shows selectivity for Mu opioid receptor over the δ receptor (Ki=132.50 nM) and the κ receptor (Ki=26.45 nM). NAQ can be used for the research of opioid withdrawal or dependence. |
|
DC72632 |
(S,S)-J-113397
(S,S)-J-113397 is an isomer of J-113397. J-113397 is an Opioid Receptor antagonist. |
256640-46-7 |
DC72633 |
Naloxonazine
Naloxonazine is a potent and selective opiate mu-1 antagonist that can also affect leishmania by regulating host coding function. |
82824-01-9 |
DC72634 |
(Rac)-SNC80
(Rac)-SNC80 is a racemate of SNC80. SNC80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist with a Ki of 1.78 nM and an IC50 of 2.73 nM. SNC80 shows antinociceptive, antihyperalgesic and antidepressant‐like effects. SNC80 has the potential for multiple headache disorders treatment. |
1217643-87-2 |
DC73473 |
AT-039
AT-039 is a potent, selective agonist of nociceptin opioid peptide (NOP) receptor, AT-039 is useful for treatment of hypertension and/or volume overload/hyponatraemic states. |
|
DC73474 |
LY2817412
LY2817412 is a potent, selective andorally active nociceptin/orphanin FQ (NOP) receptor antagonist with Ki of 0.176 nM, Kb of 0.273 nM in functional assay of receptor-mediated G-protein activation using [35S]-GTPγS binding. |
1307245-95-9 |
DC73475 |
MP135
MP135 is a potent, μ-δ opioid receptor heteromer-selective agonist with EC50 of 0.8 nM in GTPγS assays, shows functional selectivity for μ-δ heteromers over homomeric μOR and δOR and low β-arrestin2 recruitment activity. |
2677687-49-7 |
DC73476 |
Naltrexone hydrochloride
A potent, competitive antagonist for μ, κ, δ, and σ-opioid receptors with Ki of 0.0825 nM, 0.509 nM, and 8.02 nM, for MOR, KOR, and DOR, respectively. |
16676-29-2 |
DC73477 |
PIPE-3297
PIPE-3297 is a fully efficacious and selective kappa opioid receptor (KOR) agonist with functional GTPγS EC50 of 1.1 nM, Emax=91%, does not elicit β-arrestin-2 recruitment functional response. |
|
DC73478 |
PN6047
PN6047 is an orally bioavailable, G protein-biased and selective δ opioid agonist with pKi of 7.25, fully engages G protein signaling but is a partial agonist in both the arrestin recruitment and internalization assays. |
1948274-13-2 |
DC73479 |
ZYKR1
ZYKR1 is a potent, and peripherally restricted kappa opioid receptor (KOR)-selective agonist with EC50 of 0.061 nM in cAMP assays, highly selective over the mu and delta opioid receptors (EC50>10 μM). |
2253747-72-5 |
DC74621 |
Icalcaprant
Icalcaprant is a kappa-opioid receptor antagonist. |
2227384-17-8 |