Cat. No. | Product name | CAS No. |
DC11524 |
Mavacamten(MYK-461)
Featured
Mavacamten(MYK-461)is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain. |
1642288-47-8 |
DC9527 |
Methylnaltrexone (Bromide)
Featured
Methylnaltrexone Bromide is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation. |
73232-52-7 |
DC10326 |
Mozavaptan
Mozavaptan (OPC31260) is a orally effective, nonpeptide vasopressin V2 receptor antagonist with an IC50 of 14 nM. |
137975-06-5 |
DCAPI1342 |
Nepafenac
Nepafenac |
78281-72-8 |
DC12298 |
Octreotide acetate (SMS 201-995 (acetate))
Featured
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently. |
79517-01-4 |
DC10299 |
Olumacostat glasaretil
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). |
1261491-89-7 |
DC11044 |
Omidenepag Isopropyl
Featured
Omidenepag Isopropyl (DE-117, OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor; demonstrates excellent IOP-lowering activities following ocular administration in ocular normotensive monkeys, Omidenepag Isopropyl (OMDI) is a clinical candidate for the treatment of glaucoma. |
1187451-19-9 |
DC8353 |
PF-04418948
Featured
PF-04418948 is an orally active, potent, and selective EP2 receptor antagonist (IC50 = 16 nM). |
1078166-57-0 |
DCAPI1305 |
Pramiracetam
Pramiracetam |
68497-62-1 |
DC9162 |
Ranolazine HCl
Featured
Ranolazine(RS-43285) is an antianginal agent with antiarrhythmic properties that achieves its effects via a novel mechanism of action (inhibition of the late phase of the inward sodium current), without affecting heart rate or blood pressure (BP). |
95635-56-6 |
DC1048 |
Rapamycin (Sirolimus)
Featured
Rapamycin (Sirolimus, AY-22989, WY-090217) is a specific mTOR inhibitor with IC50 of ~0.1 nM. - |
53123-88-9 |
DC8185 |
Verosudil(AR-12286)
Rho-kinase (ROCK) inhibitor |
1414854-42-4 |
DC10583 |
RO 5028442
Featured
RO5028442 is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a). |
920022-47-5 |
DC8198 |
RTA-408(Omaveloxolone)
Featured
RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 and inhibits the proinflammatory transcription factor NF-κB. |
1474034-05-3 |
DC8224 |
Lifitegrast(SAR 1118)
Featured
SAR 1118 is a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist for treating dry eye. |
1025967-78-5 |
DC10925 |
SAR-100842
SAR-100842 (SAR100842) is a potent, selective, orally available antagonist of the Lysophosphatidic Acid 1 Receptor (LPA1 receptor) with IC50 of 31 nM in β-arrestin assays. |
1195941-38-8 |
DC9600 |
Senicapoc
Featured
Senicapoc(ICA17043) is a potent and selective Gardos channel blocker; blocked Ca(2+)-induced rubidium flux from human RBCs/ inhibited RBC dehydration with IC50s of 11 nM/30 nM, respectively. IC50 value: 11/30 nM [1] Target: Gardos channel in vitro: I |
289656-45-7 |
DCAPI1485 |
Silodosin
Featured
Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. Silodosin causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it ca |
160970-54-7 |
DC8592 |
Sivelestat (sodium salt hydrate)
Featured
Sivelestat(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse. |
201677-61-4 |
DC8500 |
SKQ1(Visomitin)
Featured
SKQ1 prevents amyloid-beta-induced impairment of long-term potentiation in rat hippocampal slices. |
934826-68-3 |
DC9732 |
Sufugolix(TAK-013)
Featured
Sufugolix(TAK-013) is a non-peptide, orally-active, selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (IC50 = 0.1 and 0.06 nM for affinity and in vitro inhibition, respectively). |
308831-61-0 |
DC11026 |
Tecovirimat
Featured
Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses; ST-246 is active against multiple orthopoxviruses, including vaccinia, monkeypox, c |
869572-92-9 |