| DC9600 |
Senicapoc
Featured
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Senicapoc(ICA17043) is a potent and selective Gardos channel blocker; blocked Ca(2+)-induced rubidium flux from human RBCs/ inhibited RBC dehydration with IC50s of 11 nM/30 nM, respectively.
IC50 value: 11/30 nM [1]
Target: Gardos channel
in vitro: I |
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| DCAPI1485 |
Silodosin
Featured
|
Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. Silodosin causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it ca |
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| DC8592 |
Sivelestat (sodium salt hydrate)
Featured
|
Sivelestat(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse. |
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| DC8500 |
SKQ1(Visomitin)
Featured
|
SKQ1 prevents amyloid-beta-induced impairment of long-term potentiation in rat hippocampal slices. |
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| DC9732 |
Sufugolix(TAK-013)
Featured
|
Sufugolix(TAK-013) is a non-peptide, orally-active, selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (IC50 = 0.1 and 0.06 nM for affinity and in vitro inhibition, respectively). |
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| DC11026 |
Tecovirimat
Featured
|
Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses; ST-246 is active against multiple orthopoxviruses, including vaccinia, monkeypox, c |
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| DC9148 |
Tolvaptan
Featured
|
Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation. |
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| DC11385 |
Trofinetide(NNZ2566)
Featured
|
Trofinetide (NNZ-2566) is an analog of a molecule which is derived from IGF-1 and occurs naturally in the brain. IGF-1 is a growth factor stimulated by growth hormone. |
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| DC9816 |
Valbenazine（NBI-98854）
Featured
|
Valbenazine(NBI-98854) is a potent and selective VMAT2 inhibitor.. |
|
| DC9187 |
Mosapride Citrate |
Mosapride citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist. |
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