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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC23693 PDE10A-IN-31 PDE10A-IN-31 is a potent, highly selective PDE10A inhibitor with IC50 of 2 nM for both rPDE10A and hPDE10A.
DC23701 PDE10A-IN-32 PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM)..
DC12555 PDE2 inhibitor 4 PDE2 inhibitor 4 is a potent, selective, orally available inhibitor of PDE2 with IC50 of 2 nM, displays high selectivity versus other PDE isoforms.
DC23698 PDE4D-IN-26b PDE4D-IN-26b is a potent, highly selective PDE4D inhibitor with IC50 of 0.6 nM, displays 75-fold lower activity against the PDE4A, B, and C subtypes, also exhibits 18,000-fold decreased potency against other PDE family members.
DC23807 PDEδ-IN-99 PDEδ-IN-99 is a novel potent K-Ras-PDEδ inhibitor that binds to the farnesyl binding pocket of PDEδ with Kd of 8±4 nM..
DC20047 PDGFRα kinase inhibitor 1 PDGFRα kinase inhibitor 1 is a highly selective type II PDGFRα kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFRα and PDGFRβ, respectively.
DC10904 PDM2 Featured PDM 2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM.
DCAPI1314 Pefloxacin mesylate Pefloxacin mesylate
DCAPI1528 Pemetrexed Disodium Hemipentahydrate Featured Pemetrexed Disodium Hemipentahydrate
DC12178 Pemigatinib Featured Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma.
DCAPI1224 Penicillamine (Cuprimine) Penicillamine (Cuprimine)
DC10507 Pentamidine dihydrochloride Featured Pentamidine Dihydrochloride(MP601205 dihydrochloride) is an antimicrobial agent.
DC7041 Pentostatin(Deoxycoformycin) Featured Pentostatin(Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM).
DC12194 PEO-IAA Featured PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
DC12301 Pepstatin Ammonium (Pepstatin A Ammonium) Pepstatin Ammonium is a specific aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and he
DC20494 Peptide Fz7-21 Peptide Fz7-21 is a potent, selective peptide inhibitor of Frizzled 7 receptor, inhibits exogenous WNT3A stimulated Wnt-β-catenin signaling in HEK293 cells with IC50 of 100 nM.
DC21021 Peptide P60 Featured Peptide P60 (FOXP3 inhibitor P60) is a 15-mer synthetic peptide, cell-permeable inhibitor of FOXP3, binds specifically to FOXP3; inhibits murine and human-derived Treg and improves effector T cell stimulation, overcomes the inhibitory effect of FOXP3 on the activity of the transcription factors NF-κB and NFAT, inhibits upregulation of mRNA for Foxp3 and IL-10 on effector T cells and enhances mRNA for IFN-γ after anti-CD3 stimulation; induces a scurfy-like disease in newborn mice, improves vaccine efficacy in mice model of CT26 tumor and HCV infection.
DC20495 Perhexiline Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2).
DC21821 Perhexiline maleate Featured Perhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2).
DC9143 Perindopril erbumine Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.
DC12139 Perisesaccharide B Perisesaccharide B is an oligosaccharide isolated from the root barks of Periploca sepium.
DC12137 Perisesaccharide C Perisesaccharide C is an oligosaccharide isolated from the root barks of Periploca sepium.
DC20708 Perlapine Perlapine (AW-14233.
DC12059 Pertussis Toxin Featured Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough.
DC12207 Petroselinic acid Petroselinic acid, a positional isomer of oleic acid, is isolated from the vegetable oil of Coriandrum sativum fruits.
DC12192 PF 03709270 (ulopenem etzadroxil) PF 03709270 is an orally available ester prodrug form of sulopenem, with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria.
DC22930 PF-4878691 (3M-852A) Featured PF 04878691 (PF 4878691, S 32865, 852A, 3M 001) is a selective TLR7 agonist that potently induces IFN-α and IFN-regulated proteins from human PBMC.
DC8147 PF 4800567 PF 4800567 is a selective casein kinase 1ε inhibitor; displays 22-fold greater potency towards CK1ε than CK1δ (IC50 values are 32 and 711 nM for CK1ε and CK1δ respectively).
DC21516 PF 5212372 PF 5212372 (PLA-950, ZPL-521, ZPL 5212372) is a potent, selective inhibitor of cPLA2 (cytosolic phospholipase A2α) with IC50 of 7 nM.
DC21477 PF 6260933 dihydrochloride Featured PF 6260933 is a potent, selective and orally bioavailable MAP4K4 inhibitor with kinase IC50 of 3.7 nM, cell IC50 of 160 nM.

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