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Cat. No.	Product Name	Field of Application
DC33886	Sulfo-Cyanine5.5 alkyne	Sulfo-Cyanine5.5 is a far red emitting fluorophore. It contains four sulfo groups, which provide great hydrophilicity, and aqueous solubility. The reagent can be conjugated with a variety of azides by means of copper catalyzed Click chemistry reaction.
DC33887	Sulfo-Cyanine7 alkyne	Sulfo-Cyanine7 alkyne is a sulfonated terminal alkyne for copper-catalyzed Click chemistry reaction, which possesses significant aqueous solubility, and can be conjugated with azides in aqueous environment.
DC33888	Sulfo-Cyanine7.5 alkyne	Sulfo-Cyanine7.5 is a near infrared, sulfonated cyanine dye with rigidized trimethylene chain. The fluorophore is structurally very similar to indocyanine green (ICG) dye that has been approved for human use. However, the dye has an improved quantum yield because of its rigidized structure. This is an alkyne derivative for copper catalyzed Click chemistry.
DC33889	5-isomer TAMRA alkyne	TAMRA alkyne for Click chemistry, pure 5-isomer. TAMRA (TMR, tetramethylrhodamine) is a xanthene dye. It forms a FRET pair with fluorescein. This alkyne is suitable for Copper-catalyzed Click chemistry (CuAAC).
DC33890	TAMRA alkyne, 6-isomer	Tetramethylrhodamine (TAMRA) alkyne, pure 6-isomer. TAMRA is a popular dye that is used in qPCR and other applications. It forms a FRET pair with FAM (serving as an acceptor). This product is a terminal alkyne for copper-catalyzed Click chemistry. It can be conjugated with azide groups using CuAAc reaction.
DC33891	BDP 581/591 maleimide	BDP 581/591 maleimide is a thiol reactive dye for the labeling of sulfhydryl groups of proteins and peptides. The dye is useful for a variety of applications, such as microscopy, fluorescence polarization experiments, and even ROS detection (upon reaction with ROS, the dye changes its fluorescence).
DC33892	BDP 630/650 Maleimide	BDP 630/650 is a far red emitting borondipyrromethene based fluorophore for the Cyanine5 channel. Because of its relatively long lifetime of the excited state, this dye is particularly useful for fluorescence lifetime related measurements. The reactive maleimide moiety allows to attach the dye to thiol groups in biomolecules, especially proteins and peptides.
DC33893	BDP FL maleimide	Thiol reactive BDP FL maleimide is a reactive dye for protein labeling, which has identical structure with BODIPY FL maleimide. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar to fluorescein (FAM). However, this dye exhibits very high photostability. It is non-charged, and has low molecular weight. This fluorophore is ideal for fluorescent microscopy and many other applications. The fluorophore can substitute fluorescein for almost any application, and it is compatible with any FAM-capable fluorescent instrumentation.
DC33894	BDP R6G	BDP R6G is a borondipyrromethene fluorophore whose absorption and emission spectra match those of rhodamine 6G (R6G) dye. Thiol labeling is often an option of choice for the modification of proteins. Limited number of cysteine residues in proteins allow for more site-specific labeling than NHS ester labeling of amine groups, which are encountered in large number in many proteins. This maleimide is a thiol reactive dye. Please refer to our recommended labeling protocol to achieve modification of your protein with this reagent.
DC33895	BDP TMR	BDP TMR is a bright borondipyrromethene fluorophore for the TAMRA channel. This maleimide derivative is suitable for conjuction with thiol groups as e.g. in protein side chains.
DC33896	Cyanine3 maleimide	Thiol mono-reactive Cyanine3 dye. This reagent can be used to attach Cyanine3 fluorophore (an analog of Cy3?) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cystines should be reduced with TCEP (tris-carboxyethylphosphine) or other appropriate reductant prior to the labeling. Labeling with Cyanine3 maleimide is selective, and efficient. We recommend using water-soluble Sulfo-Cyanine3 maleimide for the labeling of antibodies and other sensitive proteins.
DC33897	Cyanine5 maleimide	Cyanine5 maleimide is a mono-reactive dye which selectively couples with thiol groups (for example, with cysteines in peptides and proteins) to give labeled conjugates. Cyanine5 is an analog of Cy5?, a common fluorophore which is compatible with various instrumentation like microscopes, imagers, and fluorescence readers. For the labeling of antibodies and sensitive proteins we recommend to use the water soluble sulfo-Cyanine5 maleimide.
DC33898	Cyanine5.5 maleimide	Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5? maleimide. Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications. Cyanine5.5 can replace Cy5.5?, Alexa Fluor 680, and DyLight 680.
DC33899	Cyanine7 maleimide	Near-infrared, sulfhydryl reactive Cyanine7 dye, an analog of Cy7? maleimide. This reagent allows to attach near infrared Cyanine7 dye to proteins with free sulfhydryl groups. Labeled proteins thus obtained are used in NIR bioimaging applications. NIR imaging systems can be used to visualize distribution of labeled proteins in tissues even in live organism.
DC33901	Pyrene	Pyrene is a fluorescent hydrocarbon which emits in blue region. This is a maleimide derivative of pyrenebutyric acid which reacts with thiols. Pyrene is a useful proximity probe because two pyrene residues close to each other exhibit strong excimer fluorescence.
DC33903	Sulfo-Cyanine3 maleimide	Sulfo-Cyanine3 maleimide is a water soluble, thiol reactive dye for the labeling with hydrophilic sulfo-Cyanine3 fluorophore. This is an analog of Cy3? maleimide. This product is recommended for the labeling of antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require use of organic co-solvent.
DC33904	sulfo-Cyanine5 maleimide	A water soluble, hydrophilic sulfo-Cyanine5 maleimide (Cy5? maleimide analog). We recommend this product for protein labeling, including labeling of antibodies as a perfect replacement for Cy5? maleimide. Labeled proteins can be easily separated from unreacted dye by gel filtration, spin column purification, dialysis, electrophoresis or chromatography.
DC33905	Sulfo-Cyanine5.5 maleimide	Sulfo-Cyanine5.5 dye is a water soluble far red to NIR emitting dye which is very hydrophilic due to the presence of four sulfo groups. Sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is a perfect choice for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers. This maleimide is a thiol reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.
DC33906	Sulfo-Cyanine7 maleimide	A reactive dye with a maleimide group for the labeling of thiol groups of proteins and other biomolecules, an analog of Cy7? maleimide. Sulfo-Cyanine7 is a near infrared fluorophore which is hydrophilic and contains a rigidizing ring in its heptamethine chain that improves its photophysical properties. A great dye for various applications, including NIR imaging.
DC33907	TAMRA maleimide	Maleimide derivative of TAMRA (tetramethylrhodamine) for the labeling of thiol groups. Pure 5-isomer of TAMRA.
DC33908	TAMRA	TAMRA (aka TMR or tetramethylrhodamine) is a xanthene dye that has been used as a fluorescent label for decades. Xanthene dyes are available as two isomers (called 5- and 6-isomers) that have almost identical fluorescent properties, but need to be separated to avoid doubling and smearing of labeled product peaks or bands during chromatography or electrophoresis. This is a pure 6-isomer of TAMRA maleimide, used for the labeling of proteins and peptides via thiol (SH) groups
DC33909	Sulfo-Cyanine7.5	Sulfo-Cyanine7.5 is a near infrared fluorophore with absorption and emission ranges around 800 nm. Its spectral properties allow for the efficient leveraging of tissue NIR transparency window. The fluorophore is available as different reactive forms, this one is maleimide for the labeling of SH groups of proteins and peptides. The sulfo- version is highly hydrophilic. Such labeled biomolecules are useful in biodistribution studies and visualization in intact organisms.
DC33911	BDP FL	BDP FL is a bright and photostable dye for FAM channel. It possesses great photostability, quantum yield approaching unity. This dye is well-suited for microscopy and fluorescence polarization assays. Hydrazide group provides easy conjugation with carbonyl compounds (aldehydes, and ketones).
DC33915	Cyanine5 Boc-hydrazide	Boc-protected Cyanine5 hydrazide reactive dye for the labeling of aldehydes and ketones. Boc- (tert-butoxycarbonyl) protective group can be removed with trifluoroacetic acid, or other strong acid. Reactive hydrazide is formed, which can then couple with various carbonyl groups yielding Cyanine5-labeled molecules.
DC33916	Cyanine5 hydrazide	Cyanine5 hydrazide is a reactive dye for the labeling of aldehydes and ketones, an analog of Cy5? hydrazide. This dye reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. Examples are proteins subjected to oxidative stress, glycosylated proteins pre-activated by periodate oxidation (including antobodies), and oligonucleotides with aldehyde moieties. Cyanine5 hydrazide replaces carbonyl-reactive Cy5?, Alexa Fluor 647, DyLight 649 dyes.
DC33917	Cyanine7 hydrazide	Hydrazide derivative of Cyanine7, a NIR fluorescent dye, an analog of Cy7?. This variety of heptamethine fluorophore contains a six-membered ring rigidizing the polymethine chain which allows to increase quantum yield by 20% compared to parent structure. Hydrazide reacts quickly and smoothly with aldehydes and ketones yielding stable hydrazone products. This reaction is also good for the labeling of glycoproteins after periodate oxidation.
DC33919	FAM hydrazide 5-isomer	Many natural and synthetic molecules contain aldehyde or ketone carbonyl groups. These carbonyls react with hydrazides with the formation of hydrazones. The reaction is spontaneous at pH values around neutral, and the resulting hydrazones are very stable. Compounds containing 1,2-diol function, like sugars, can be oxidized with sodium periodate with the formation of carbonyl compounds for the subsequent modification with hydrazides. This is an efficient method for the labeling of glycoproteins (like antibodies), and polysaccharides. FAM hydrazide is a hydrazide label for the attachment of fluorescein, a bright dye for 488 nm channel, to carbonyl compounds
DC33920	FAM hydrazide 6-isomer	Sulfo-Cyanine5.5 (analog of Cy5.5?) is a water-soluble, far red emitting fluorophore. Due to four sulfo-groups, the dye possesses negative charge in neutral pH, and very high hydrophilicity. As a cyanine dye, sulfo-Cyanine5.5 shows very low dependence of the fluorescence on pH, and very high extinction coefficient.
DC33921	Pyrene hydrazide	Pyrene hydrazide is a carbonyl reactive dye for the attachment of pyrene polycyclic aromatic hydrocarbon residues to aldehydes and ketones. Pyrene is a blue-emitting fluorescent label which is especially useful as a proximity probe. When two pyrene residues are located close to each other, a longer-wavelength excimer fluorescence can be detected. Pyrene can also be FRET donor to other fluorophores. Its excited state possesses an unusually long lifetime of more than 100 ns, which allows to use this fluorophore in time-gated experiments.
DC33923	BDP 558/568 carboxylic acid	BDP 558/568 is a universal borondipyrromethene dye with emission in the yellow region of the spectrum. This derivative is a free carboxylic acid.

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