| DC36090 |
Avarone |
Avarone is a cytostatic agent which has potent antileukemic activity in vitro. Avarone also displays antibacterial and antifungal activities against a limited range of microorganisms. |
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| DC36091 |
(-)-Averantin |
Averantin is an Aflatoxin B(1) precursor. |
|
| DC36092 |
AX-048 |
AX-048is a potent group IVA cPLA2 inhibitor. The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes. |
|
| DC36093 |
Azlin |
Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin |
|
| DC36094 |
Aztreonam E-isomer |
SQ-28429 is a synthetic monobactam. |
|
| DC36095 |
Azelastine hydrochloride (S)- |
(S)-Azelastine hydrochloride is an antihistamine which has been shown to down-regulate H1R, M1R and M3R levels. This compound has also been shown to inhibit HNEpC proliferation. |
|
| DC36096 |
(R)-Azelastine hydrochloride |
(R)-Azelastine hydrochloride is an antihistamine which has been shown to down-regulate H1R, M1R and M3R levels. This compound has also been shown to inhibit HNEpC proliferation. |
|
| DC36097 |
Azilect |
Rasagiline is a selective and irreversible propargylamine inhibitor of monoamine oxidase type-B (MAO-B) that is not metabolized to amphetamine derivatives. Rasagiline exhibits neuroprotective and antiapoptotic activity against ischemia and several neurotoxins, including SIN-1, MPTP, 6-hydroxydopamine, and N-methyl-(R)-salsolinol. |
|
| DC36098 |
ATB-337 |
S-Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). S-diclofenac may protect against doxorubicin-induced cardiomyopathy by ameliorating cardiac gap junction remodeling. |
|
| DC36099 |
Abbott 36581 citrate |
Butamirate citrate is an anti-tussive which may be used in the treatment of non-productive (dry) cough. |
|
| DC36100 |
Actosin |
Cyclocumarol is an anticoagulant similar to but less potent than warfarin. This product may cause hemorrhaging if used indiscriminately. |
|
| DC36101 |
295 C 51 |
Triprolidine hydrochloride anhydrous is a Histamine H1 antagonist used in allergic rhinitis, asthma, and urticaria. |
|
| DC36102 |
Aciclovir EP Impurity F |
N2-Acetylaciclovir, also known as Aciclovir EP Impurity F, is an impurity of Aciclovir. |
|
| DC36103 |
Doxycycline monohydrate |
Doxycycline monohydrate is a synthetic tetracycline derivative with similar antimicrobial activity. |
|
| DC36104 |
(+)-Razoxane hydrochloride |
Dexrazoxane hydrochloride is a cardioprotectant. Studies have shown that usage of this drug before anthracycline chemotherapy in pediatric patients with AML may improve cardiac function indices such as ejection fraction and shortening fraction. Adding dexrazoxane to doxorubicin in adjuvant therapy patients may lead to higher rates of bone marrow suppression, more febrile neutropenia events, and dose reductions. |
|
| DC36105 |
Adrenalone hydrochloride |
Adrenone hydrochloride displays antineoplastic activity and has been shown to inhibit growth of Ehrlich ascites tumors in mice. |
|
| DC36106 |
Adipostatin A |
Adipostatin A is an inhibitor of glycerol-3-phosphate dehydrogenase (GPDH). It prevents triglyceride accumulation in 3T3-L1 cells and is cytotoxic against fibroblast carcinoma KB cell lines. It also shows larvicidal activity against A. aegypti. |
|
| DC36107 |
(±)-Alphamethrin |
alpha-Cypermethrin is a synthetic pyrethroid pesticide. |
|
| DC36108 |
Abamectin
Featured
|
Abamectin is a mixture of the macrocyclic lactones Avermectin B1a and Avermectin B1b. It has both insecticidal and anthelmintic actions and is used in both agriculture and veterinary medicine. Abamectin can inhibit nicotinic acetylcholine receptors of worms and can also inhibit chikungunya and yellow fever viruses. It is sometimes used for mosquito control. |
|
| DC36109 |
Abbocillin |
Penicillin G procaine is a semisynthetic antibiotic prepared by combining penicillin G with Procaine. |
|
| DC36110 |
IMS2186 |
IMS2186 is an anti-proliferative and anti-angiogenic agent. IMS2186 blocks the cell cycle at G2 and inhibits the production of PGE2/TNF-α. IMS2186 inhibits cell growth in vitro in tumor cells, non-transformed fibroblasts, and retinal pigment epithelial cells. IMS2186 inhibits angiogenesis (IC50 = 0.1 μM) and cell migration. Intraocular injection of IMS2186 could be a long-lasting effective treatment for CNV (choroidal neovascularization) in AMD (age-related macular degeneration) with a reduction in scarring and related visual loss. |
|
| DC36111 |
ML230 |
ML230 is a specific inhibitor of the ABC-binding cassette trasporter BCRP (MRP-1; ABCG2). The compound ML 230 is 36-fold selective for BCRP over MDR-1 (Pgp; ABCB1) with IC50 values of 0.013 and 4.7 mM, respectively. |
|
| DC36112 |
L2-b |
L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples. |
|
| DC36113 |
(S)-Apomorphine Hydrochloride |
(S)-Apomorphine Hydrochloride is a Dopamine (D1 and D2) receptor agonist which may be effective in the treatment of Parkinson's disease. |
|
| DC36114 |
AMBMP hydrochloride |
AMBMP hydrochloride is a Wnt canonical signaling activator and tubulin polymerization inhibitor. |
|
| DC36115 |
Emetine Dihydrochloride Hydrate |
Emetine is a drug used as both an anti-protozoal and to induce vomiting. It is produced from the ipecac root. It takes its name from its emetic properties. Emetine protects mice from enterovirus infection by inhibiting viral translation. Emetine Synergizes with Cisplatin to Enhance Anti-Cancer Efficacy against Lung Cancer Cells. Emetine exhibits anticancer activity in breast cancer cells as an antagonist of Wnt/β?catenin signaling. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. |
|
| DC36116 |
AG-1777 |
Lansoprazole sulfide is an impurity of Lansoprazole -- a gastric pump inhibitor. |
|
| DC36117 |
AG-028458 |
Axitinib sulfoxide is a major metabolite of Axitinib --- a VEGFR tyrosine kinase inhibitor. Axitinib may be useful in cancer therapy. |
|
| DC36118 |
Ageratochromene |
Precocene II is an antiallotropin compound capable of inhibiting juvenile hormone biosynthesis. Precocene II has antibacterial, antifungal, insecticidal, and antioxidant activities. |
|
| DC36119 |
AGN-191129 |
AGN-191129, also known as Prostaglandin F2α alcohol methyl ether (PGF2α-OMe), is an analog of PGF2α in which the C-1 carboxyl group has been replaced by an O-methyl ether. The compound is reported to retain ocular hypotensive properties, but the receptors which mediate this activity have not been clearly documented. |
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