| DC36487 |
Cyclosporin B |
Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosuppressant activity. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity. Cyclosporin B displays antiviral properties, inhibiting entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts. |
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| DC36488 |
3,5-Diiodo-L-thyronine |
3,5-Diiodo-L-thyronine, Iodinated thyronine hormone. regulating gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance. |
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| DC36491 |
Zanamivir hydrate |
Zanamivir hydrate is neuraminidase inhibitors (NAIs) and is used worldwide for treatment and prophylaxis of influenza caused by influenza A and B viruses. |
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| DC36492 |
Anpirtoline hydrochloride |
Anpirtoline HCl is highly potent 5-HT1B receptor agonist which decreases central serotonin synthesis and attenuates aggressive behavior in vivo. Anpirtoline HCl also acts as an antagonist at 5-HT3 receptors and is brain penetrant. Anpirtoline is a receptor agonist with antinociceptive/antidepressant-like actions in rodents. |
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| DC36493 |
Dideoxyadenosine
Featured
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Dideoxyadenosine is konwn as 2′,3′-Dideoxyadenosine (ddA), a specific adenylyl cyclase inhibitor, is useful in biological process and pathway studies involving adenylyl cyclase activity and cAMP pool modulation. |
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| DC36494 |
D21-2393 |
D21-2393 is known as Edoxaban 4-Carboxylic Acid. Subjects received a single-oral-dose of edoxaban 30-90?mg in each study occasion under fasting condition. Serial blood samples were collected to measure the plasma concentrations of edoxaban and its major active metabolite D21-2393. Meanwhile, PT, INR, aPTT were measured pre- and post-dose. Safety was assessed. 4.?The effects of edoxaban on all pharmacodynamic biomarkers were concentration-dependent and linearly-correlated to plasma level of the compound. Minor bleeding was the most commonly reported adverse events. |
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| DC36495 |
Carboxin |
Carboxin is a systemic agricultural fungicide and seed treatment agent. Carboxin kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc. |
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| DC36496 |
Bauerenol |
Bauerenol is a triterpenoid from Indian Suregada angustifolia, is isolated from the stem bark of Acronychia pedunculata., Induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma (HepG2) cells. Bauerenol is an Antitrypanosomal Agent. |
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| DC36497 |
Diazoacetic ester |
Diazoacetic ester is also known as Ethyl Diazoacetate. Ethyl Diazoacetate is used in the synthesis of Arteludovicinolide A as well as pyrimidoazepine analogs as seritonin 5-HT2A/C receptor ligands for treatment of obesity. This compound contains solvent for added stability. |
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| DC36498 |
Oxytetracycline |
Oxytetracycline is analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions. Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins. Without these proteins, the bacteria cannot grow, multiply and increase in numbers. Oxytetracycline therefore stops the spread of the infection and the remaining bacteria are killed by the immune system or eventually die. Oxytetracycline is a broad-spectrum antibiotic, active against a wide variety of bacteria. However, some strains of bacteria have developed resistance to this antibiotic, which has reduced its effectiveness for treating some types of infections. |
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| DC36499 |
Diolamine |
Diolamine is also known as Diethanolamine. Diethanolamine is used in the preparation of morpholine and diethanolamides, which is an active ingredient in cosmetics and shampoos. It acts as a surfactant and a corrosion inhibitor. It is utilized to remove hydrogen sulfide and carbon dioxide from natural gas. Further, it is an intermediate used in the rubber chemicals, as a humectant and a softening agent, and as an emulsifier and dispersing agent in agricultural chemicals. In addition to this, it is used in cutting oils, cleaners, soaps, polishers, and pharmaceuticals. |
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| DC36500 |
Fensulfothion |
Fensulfothion is used as an insecticide, nematocide and mosquito larvicide. |
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| DC36501 |
Piperidolate hydrochloride |
Piperidolate hydrochloride is an antimuscarinic, Also a potential inhibitor of human glutathione transferase P1-1. Piperidolate HCl could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs). |
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| DC36502 |
Diazinon |
Diazinon is a cholinesterase inhibitor that is used as an organothiophosphorus insecticide. Diazinon is active against approximately 120 species of insects and pests.1 It is metabolized into the cholinesterase inhibitors monothionotetraethyl pyrophosphate, dithionotetraethyl pyrophosphate, and triethylthionophosphate in vivo, which induce vomiting, fasciculation with muscular twitching, paralysis, and death (LD50 = 125 mg/kg) in rats. Diazinon induces formation of capsular adhesion in the kidneys and ulcer formation in the duodenum of dogs as well as mucosal erosion and serosal seepage in the intestines of mini pigs. Formulations containing diazinon were previously used as agricultural pesticides. |
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| DC36503 |
Calcium carbonate |
Calcium carbonate is a naturally occurring compound used as a calcium supplement and antacid. Also used in laboratories as a buffer. Shown in renal-disease patients with hyperphosphatemia to contain phosphate binding power, but may result in hypercalcaemia or alkalosis. Other experiments have successfully utilized calcium carbonate as a calcium control in comparison studies. |
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| DC36504 |
Chlorthal-dimethy |
Chlorthal-dimethy is herbicide as agricultural chemica. it has Reproductive Effect. |
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| DC36505 |
Chlorothalonil |
Chlorothalonil is a an organochlorine, broad-spectrum and non-systemic fungicide[2], which can be widely used in agriculture, in order to have a control on foliar pathogens. Chlorothalonil is a broad spectrum fungicide with carcinogenic and aquatic toxicity properties. |
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| DC36506 |
Sodium methanearsonate |
Sodium methanearsonate is also known as Monosodium Acid Methane Arsonate Sesquihydrate. It is an environmental toxic compound. It also functions as a commonly used herbicide for weed control in grass. |
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| DC36507 |
Desacetylcephalothin sodium |
Deacetylcephalothin Sodium Salt, is an impurity in the synthesis of Cefalonium (C236800) and an analog of Cephalothin (C261150) a first-generation cephalosporin antibiotic used as a long-acting intramammary cerate for infusion of dairy cows. |
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| DC36508 |
Poliglusam |
Poliglusam is also known as Chitosan. Chitosan is a linear polysaccharide composed of randomly distributed β-(1→4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine (acetylated unit). It is made by treating the chitin shells of shrimp and other crustaceans with an alkaline substance, like sodium hydroxide. Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS. |
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| DC36509 |
Dacisteine |
Dacisteine, also known as D-cysteine. protects primary cultures of cerebellar neurons from oxidative stress induced by hydrogen peroxide and attenuates ischaemia-reperfusion injury in the kidney more than L-cysteine. A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells. provides a new therapeutic approach to deliver hydrogen sulphide to specific tissues. |
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| DC36510 |
Dacuronium bromide |
Dacuronium bromide is an aminosteroid neuromuscular blocking agent Pancuronium (P178500) with much weaker activity which was never marketed. It acts as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR). |
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| DC36511 |
Thiofanox |
Thiofanox is a chemical compound used in acaricides and insecticides. Shows potential systemic & contact insecticidal properties against certain phytophagous pests. |
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| DC36513 |
Saccharin sodium |
Saccharin sodium is a type of artificial or nonnutritive sweetener. It is 200 to 700 times sweeter than sucrose but has a bitter aftertaste. Saccharin and its salts do not occur naturally. Saccharin sodium is used in the production of various foods and pharmaceutical products including soft drinks, candy, biscuits, jams, chewing gum, tinned fruit, medicine and toothpaste. |
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| DC36514 |
Saccharin, sodium salt hydrate |
Saccharin, sodium salt hydrate is used as an artificial sweetener in drinks, candies, cookies, medicines and toothpaste. It is used in the food industry and for sweetening diabetes diet. It is also used as a synthetic sweet ignorance agent. It finds application in a variety of beverages, foods, cosmetics and pharmaceuticals to provide sweetness without adding calories. It is involved as a nickel electroplating brightener, chemical intermediate, animal feed sweetener and anaerobic adhesive accelerator. Saccharin, sodium salt hydrate is the first generation′ synthetic sugar alternative that has been studied for its carcinogenic potential. Incompatible with strong oxidizing agents. |
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| DC36515 |
Molybdenum disulfide |
Molybdenum disulfide is insoluble in water and dilute acids. Molybdenum disulfide is the inorganic compound with the formula MoS2. This black crystalline sulfide of molybdenum occurs as the mineral molybdenite. It is the principal ore from which molybdenum metal is extracted. |
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| DC36516 |
Estrogens |
Estrogens, conjugated is a pharmaceutical preparation containing a mixture of water-soluble, conjugated estrogens derived wholly or in part from URINE of pregnant mares or synthetically from ESTRONE and EQUILIN. Conjugated estrogens are a medicine that contains a mixture of estrogen hormones. It is used to treat moderate to severe hot flashes, changes in and around the vagina, and other symptoms of menopause or low amounts of estrogen (hypoestrogenism). This medicine is also used to prevent osteoporosis (thinning of the bones) after menopause. Conjugated estrogens tablet is also used to treat symptoms of breast and prostate cancer that have spread through the body in men and women. It is also used to treat certain conditions in women before menopause if their ovaries do not make enough estrogen naturally. |
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| DC36517 |
Imazamethabenz |
Imazamethabenz is also known as Imazamethabenz-methyl, it is is a herbicide. A post-emergence herbicide, usually used as the methyl ester, to control grasses and some dicotyledonous weeds. Also pesticide transformation product. Activity and selectivity are due to differential de-esterification to the active parent acid in target and crop species. Imazamethabenz-methyl is used on cereals and sunflowers, especially against wild oat. |
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| DC36518 |
Butyl benzoate |
Butyl benzoate as involatile solvent, for sampling of isocyanates with silica gel solid phase extraction. Butyl benzoate has been used as preservative in commercial cosmetic lotions. 3-(tert-Butyl)-4-hydroxyphenyl 2,4-dichlorobenzoate (1) was discovered as a moderate FXR antagonist. To improve the potency and the stability of the hit 1, forty derivatives were synthesized and SAR was systematically explored. The results turn out that replacing the 2,4-dichlorophenyl with 2,6-dichloro-4-amidophenyl shows great improvement in potency, replacing the benzoate with benzamide shows improvement in stability and slight declining of potency and 3-(tert-butyl)-4-hydroxyphenyl unit is essential in obtaining the FXR antagonistic activity. |
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| DC36519 |
Acid blue 3 |
Acid blue is also known as Patent Blue V, and is a dark bluish synthetic triphenylmethane dye used as a food coloring. As a food additive, it has E number E131. It is a sodium or calcium salt of [4-(α-(4-diethylaminophenyl)-5-hydroxy- 2,4-disulfophenylmethylidene)-2,5-cyclohexadien-1-ylidene] diethylammonium hydroxide inner salt. The color of the dye is pH-dependent. In aqueous solution, its color will vary from a deep blue in alkaline or weakly acidic medium to a yellow–orange in stronger acidic conditions. It is useful as a pH indicator for the range 0.8–3.0. The structure is also redox-sensitive, changing from a reduced yellow form to an oxidized red form in solution. The reduction potential of around 0.77 volts is similar to that of other triphenylmethane dyes. It is usable as a reversible redox indicator in some analytical methods. |
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