DC36887 |
Pachycarpine |
Pachycarpine may decrease hyperexcitability through the activation of the M2 and M4 subtypes of mAChRs, which is a probable mechanism of action that together with its systemic effects may favor its anticonvulsant effects against seizures and SE. |
|
DC36888 |
PU 23 |
PU 23 is a multidrug resistance protein (MRP) 4 inhibitor. |
|
DC36889 |
A 33 |
A 33 is a potent and selective PDE4B inhibitor. |
|
DC36890 |
Kirromycin |
Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. |
|
DC36891 |
U 37883A |
U 37883A is an antagonist of vascular ATP-sensitive potassium channel openers. |
|
DC36892 |
DPTIP |
DPTIP is a potent and selective N-SMase2 inhibitor and brain penetrant. |
|
DC36893 |
CAY10443 |
CAY10443 is an apoptotic activator. |
|
DC36894 |
SKLB-23bb
Featured
|
SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability. |
|
DC36895 |
CM 10
Featured
|
CM 10 is an ALDH1A inhibitor that depletes CD133+ cancer stem cells. |
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DC36896 |
Psychosine |
Psychosine is an intermediate in the biosynthesis of cerebrosides. It is formed by reaction of sphingosine with UDP-galactose and then itself reacts with fatty acid-Coenzyme A to form the cerebroside. |
|
DC36897 |
Phleomycin |
Phleomycin is a glycopeptide antibiotic from Streptomyces whose cytotoxic action results from its ability to cause DNA fragmentation. |
|
DC36898 |
BSJ-03-204
Featured
|
BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-03-204 is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC), with IC50s of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-03-204 does not induce IKZF1/3 degradation and has anti-cancer activity. |
|
DC36899 |
JTP 103237 |
JTP 103237 is a potent and selective monoacyglycerol acyltransferase 2 (MOGAT2) inhibitor. |
|
DC36900 |
HODHBt |
HODHBt is a STAT5-SUMO protein-protein interaction inhibitor. |
|
DC36901 |
Sulfo-EMCS |
Sulfo-EMCS is a heterobifunctional amine- and sulfhydryl-reactive crosslinker. |
|
DC36902 |
Tryptophol |
Tryptophol is an indole that has been found in plants, bacteria, fungi, and sponges and has diverse biological activities, including antifungal, sleep-promoting, and quorum-sensing-related properties. |
|
DC36903 |
K252d |
K252d is an indolocarbazole alkaloid found in Nocardiopsis. It is a PKC inhibitor that inhibits PKC isolated from rat brain, as well as, calcium- and calmodulin-dependent phosphodiesterase isolated from bovine heart. |
|
DC36904 |
Etidin |
Etidin is a geroprotective agent. |
|
DC36905 |
ZAP 180013 |
ZAP-180013 inhibits interaction with ITAMs (immunoreceptor tyrosine-based activation motifs). |
|
DC36906 |
IDO-IN-3 |
IDO-IN-3 is an inhibitor of indoleamine-2,3-dioxygenase 1. |
|
DC36907 |
Dieugenol |
Dieugenol is a neolignan with antioxidative and antiparasitic activities. |
|
DC36908 |
CI 26150 |
CI 26150 is a coloring agent used to assess myelin repair in demyelinating diseases. |
|
DC36909 |
Syringaldazine |
Syringaldazine is a chromogenic agent used for detection of laccase in sporophores of wood rotting fungi. |
|
DC36910 |
Squalane |
Squalane is used as a lubricant for fatty acid surfactant films adsorbed on iron oxide surfaces |
|
DC36911 |
Thiodigalactoside |
Thiodigalactoside is a potent inhibitor of galectin-1 that suppress tumor growth by inhibiting multiple cancer enhancing activities of galectin-1, including immune cell dysregulation, angiogenesis and protection against oxidative stress. |
|
DC36912 |
Thioindigo |
Thioindigo is an organosulfur compound that is used to dye polyester fabric. |
|
DC36913 |
Bemotrizinol |
Bemotrizinol is a UVA absorber used as a topical sunscreen. |
|
DC36914 |
Monazomycin |
Monazomycin is a positively charged, polyene-like antibiotic. |
|
DC36915 |
U 90042 |
U 90042 is a GABAA receptor ligand with sedative and hypnotic properties. |
|
DC36916 |
Medrysone |
Medrysone is an anti-inflammatory steroid. |
|