| DC37867 |
N-Formylmethionine |
N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells. |
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| DC37868 |
N-(1-oxohexadecyl)-L-Aspartic acid |
Palmitoyl-L-aspartic acid is a natural N-acylaspartate that inhibits Hedgehog signaling after stimulation with Smoothened agonist or non-sterol-modified Sonic Hedgehog. It does not alter the activity of cannabinoid receptors or fatty acid amide hydrolase. |
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| DC37869 |
N-Iminoethyl-L-lysine dihydrochloride |
L-NIL HCl is a relatively selective inhibitor of iNOS. It exhibits IC50 values of 0.4-3.3 μM for iNOS as opposed to 8-38 and 17-92 μM for eNOS and nNOS, respectively. L-NIL effectively inhibits iNOS both in vitro and in vivo.4,5,3 L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major. |
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| DC37870 |
L-NIO HCl |
L-NIO HCl is a non-selective inhibitor of all NOS isoforms. The Ki values for nNOS (rat), eNOS (bovine), and iNOS (mouse) are 1.7, 3.9, and 3.9 μM, respectively. L-NIO inhibits endothelial-dependent relaxation induced by acetylcholine in rat aortic rings and hypotensive responses to acetylcholine and bradykinin. |
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| DC37871 |
Canthaxanthin |
Canthaxanthin is a trans-carotenoid pigment widely distributed in nature. The compound is used as an oral suntanning agent and as a food and drug coloring agent. Oral ingestion of the compound causes canthaxanthin retinopathy. |
|
| DC37872 |
Tris(benzyloxycarbonyl)arginine |
NSC-120011, also known as Tris(benzyloxycarbonyl)arginine, is a bioactive chemical. |
|
| DC37873 |
Tetragastrin |
Tetragastrin is the C-terminal tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin. |
|
| DC37874 |
Arginylphenylalaninamide |
Arginylphenylalaninamide is a fragment of FMRamide; may be used as a neurotransmitter or neuromodulator by optic lobe neurons of different types. |
|
| DC37875 |
Aspartame acesulfame |
Aspartame acesulfame is an artificial sweetener that is 350 times more sweet as sucrose. |
|
| DC37876 |
Dansylphenylalanine |
Dansylphenylalanine is a typical fluorescent analyte. |
|
| DC37877 |
Ochratoxin C |
Ochratoxin C is a toxic metabolite from Aspergillus orchraceus. |
|
| DC37878 |
Indoleacetyl phenylalanine |
Indoleacetyl phenylalanine is an indole-3-acetyl-amino acid conjugate involved in regulatory mechanisms for the control of auxin activity during physiological and pathophysiological responses. |
|
| DC37879 |
Neotame |
Neotame is a white colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in variety of foods. It is manufactured from aspartame and 3,3-dimethylbutyraldehyde in a one-step chemical synthesis process. |
|
| DC37880 |
Advantame anhydrous |
Advantame anhydrous is a non-caloric sweetener. The U.S. Food and Drug Administration has approved advantame for general use in foods and beverages except meat and poultry as a food additive. It is synthesized from isovanillin and aspartame. |
|
| DC37881 |
Alanylphenylalanine |
Alanylphenylalanine may be used in physicochemical studies or to evaluate dipeptide separation technologies. It can also be used for studying cell uptake mechanisms, dipeptide metabolism or cell growth supplementation benefits. |
|
| DC37882 |
beta-Casomorphin 5 |
beta-Casomorphin 5 is an opioid receptor agonist, is a member of the β-casomorphin peptide family derived from β-casein. β-casomorphins are used to study their differential effects on processes such as hyperglycemia, oxidative stress, opioid signalling and immunosuppression. |
|
| DC37883 |
PPACK |
PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). It has been used as an anticoagulant (100 μM) and to study thrombin-mediated fibrin deposition, angiogenesis, and proinflammatory processes. |
|
| DC37884 |
Morphiceptin |
Morphiceptin is a synthetic tetrapeptide with morphinelike activities, highly specific for morphine receptors, but not for enkephalin receptors; is the amide of a fragment of the milk protein beta casein; deproceptin is the D-Pro(4)-isomer. |
|
| DC37885 |
Captopril disulfide |
Captopril disulfide is a metabolite of Captopril. A new antihypertensive agent. |
|
| DC37886 |
Oleoyl proline |
Oleoyl proline is an N-acyl amine that has been detected in bovine brain extracts and D. melanogaster larvae using mass spectrometry. In a preclinical model of pain, mice lacking fatty acid amide hydrolase (FAAH KO) had decreased N-oleoyl proline levels in lumbar spinal cord after capsaicin administration (1 μg/10 μl).3 N-Oleoyl proline also has surfactant properties (critical micelle concentration = 4.8 μM). |
|
| DC37887 |
Enalapril |
Enalapril is an angiotensin-converting enzyme inhibitor that is used to treat HYPERTENSION and HEART FAILURE. |
|
| DC37889 |
Hydroxyproline palmitamide |
Hydroxyproline palmitamide is a bioactive chemical. |
|
| DC37890 |
Fosinoprilat |
Fosinoprilat is an active phosphinic acid metabolite of prodrug fosenopril, which is activated by esterases in vivo; binds zinc with phosphinic acid group. |
|
| DC37891 |
Lysobactin |
Lysobactin, also known as katanosin B, is a potent antibiotic with in vivo efficacy against Staphylococcus aureus and Streptococcus pneumoniae. It was previously shown to inhibit peptidoglycan (PG) biosynthesis. |
|
| DC37892 |
Sophoridin |
Sophoridin is an anticancer agent, with a promising anti-rumor effect and lower toxicity. Anti-inflammatory. |
|
| DC37893 |
L-Sulforaphane |
L-Sulforaphane is a naturally occurring isothiocyanate found in high concentration in a variety of brocolli. Acts as a potent inducer of detoxification enzymes. L-Sulforaphane displays bactericidal activity to both the intracellular and extracellular forms of H. pylori. |
|
| DC37894 |
(-)-Synephrine |
Synephrine (R-isomer), also known as (-)-Synephrine, inhibits eotaxin-1 expression via the STAT6 signaling pathway. |
|
| DC37895 |
Tenuazonic acid |
Tenuazonic acid is a metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin. |
|
| DC37896 |
Clindamycin |
Clindamycin is an antibacterial agent that is a semisynthetic analog of LINCOMYCIN. |
|
| DC37897 |
Pirlimycin hydrochloride |
Pirlimycin Hydrochloride is a semi-synthetic lincosaminide antibiotic. Pirlimycin Hydrochloride is a Clindamycin analog. |
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