Cat. No. | Product name | CAS No. |
DC21990 |
AGI-14100
AGI-14100 (AGI14100) is a novel potent and selective, orally available IDH1 mutant inhibitor. |
1448346-43-7 |
DC12225 |
AGL-2263
AGL-2263 is an insulin receptor (IR) blocker. |
638213-98-6 |
DC7767 |
AGN 194310
AGN 194310(VTP-194310) is a potent and selective pan-RARs agonist with Kd values of 3/2/5 nM for RARα/β/γ respectively. |
229961-45-9 |
DC20304 |
AGPS-IN-1a
AGPS-IN-1a is a potent inhibitor of the ether lipid-generating enzyme alkyl-glycerone phosphate synthase (AGPS), selectively lowers ether lipid levels in several types of human cancer cells and impairs their cellular survival and migration.. |
1807978-35-3 |
DC12535 |
AgrA inhibitor F19
AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens, blocks staphylococcal transcription factor AgrA from binding to its promoter and inhibits toxin and virulence factor transcription. |
1532534-68-1 |
DC7632 |
AHAS inhibitor(BTB06584)
Featured
AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB). |
219793-45-0 |
DC8735 |
AHU-377 hemicalcium salt
Featured
AHU-377 is an inhibitor of neprilysin with IC50 value of 5 nM. |
1369773-39-6 |
DC8734 |
AHU-377(Sacubitril)
AHU-377 is an inhibitor of neprilysin with IC50 value of 5 nM. |
149709-62-6 |
DC20305 |
AI-10-104
Featured
AI-10-104 is a small molecule inhibitor that interferes with CBFβ binding to RUNX proteins with IC50 of 1.25 uM in FRET assays. |
1881276-00-1 |
DC9402 |
Letermovir(AIC-246)
Featured
AIC246 is a novel anti-CMV compound which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. |
917389-32-3 |
DC23900 |
AICAR phosphate
Featured
AICAR phosphate (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes. |
681006-28-0 |
DC12402 |
AJM300
AJM300 (AJM 300, AJM-300) is a novel potent, selective, oraaly available alpha 4 integrin antagonist fortreatment of active ulcerative colitis.. |
401905-67-7 |
DC23660 |
AK106-001616(AK 106-001616)
AK106-001616 (AK 106-001616) is a potent and selective inhibitor of cytosolic phospholipase A2 (cPLA2) with IC50 of 3.8 nM (human cPLA2 enzyme). |
590416-75-4 |
DC21991 |
AK306
AK306 is a small molecule clathrin heavy chain (CLTC/CHC) binding compound that induces arrest and apoptosis of the HCT116 colon cancer cell line with EC50 of 50 nM. |
|
DC23789 |
AK778
Featured
AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen, competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix. . |
328906-67-8 |
DC20649 |
AKB-9778
Featured
AKB-9778 is a potent, selective inhibitor of vascular endothelial protein tyrosine phosphatase (VE-PTP) with IC50 of 17 pM. |
|
DC12158 |
AKOS B018304
Featured
AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position. |
6308-22-1 |
DC10941 |
AKR1C3 inhibitor KV-37
AKR1C3 inhibitor KV-37 is a potent, isoform selective and metabolically stable inhibitor of Aldo-keto reductase 1C3 (AKR1C3) with IC50 of 66 nM, displays 109-fold selectivity over AKR1C2. |
1954693-22-1 |
DC9677 |
AL 082D06(D-06)
Featured
AL 082D06(D-06) is the first selective, nonsteroidal glucocorticoid receptor (GR) antagonist with Ki of 210 nM, exhibits excellent selectivity against AR, PR, MR and ER(Ki > 10 uM). |
256925-03-8 |
DC20260 |
AL-335
Featured
AL-335 is a potent inhibitor of hepatitis C virus (HCV) NS5B polymerase with IE50 values as low as 70 nM. AL-335 is potentially useful for the Treatment of Hepatitis C Infection. AL-335 demonstrated high levels of the nucleoside triphosphate in vitro in primary human hepatocytes and Huh-7 cells as well as in dog liver following a single oral dose. AL-335 was selected for the clinical development where it showed promising results in phase 1 and 2 trials. |
1613589-09-5 |
DC21111 |
AL-9
AL-9 is a small molecule HCV replication inhibitor with EC50 of 0.29 and 0.75 uM for genotype 1b and 2a, inhibits purified PI4KIIIα with IC50 of 0.57 uM. |
869218-90-6 |
DC20652 |
ALB-127158
ALB-127158 is a potent (IC50=7 nM), selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1) for treatment of obesity.. |