Cat. No. | Product name | CAS No. |
DC11989 |
BMT-090605
BMT-090605 (BMT 090605, BMT090605) is a potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50 0.6 nM. |
1551403-51-0 |
DC23998 |
BMX-IN-1
Featured
BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity. |
1431525-23-3 |
DC23754 |
BNC-1
BNC-1 is a small molecule modulator of Amyloid pathology by promoting phosphorylation and activation of Elk-1, a transcriptional repressor of presenilin-1 but not presenilin-2. |
96335-59-0 |
DC7773 |
BNC-105
Featured
BNC105 is a novel tubulin polymerization inhibitor that selectively disrupts tumor vasculature and displays single-agent antitumor efficacy. |
945771-74-4 |
DC23262 |
BNM-III-170
BNM-III-170 is a small-molecule CD4-mimetic compound that enhances vaccine efficacy against HIV-1 challenge in vivo. |
1859189-54-0 |
DC23243 |
BNM-III-170 trifluoroacetate
BNM-III-170 TFA salt is a small-molecule CD4-mimetic compound that enhances vaccine efficacy against HIV-1 challenge in vivo. |
1859189-55-1 |
DC20823 |
BNS-22
BNS-22 is a small-molecule inhibitor of DNA topoisomerase II, inhibits kinetoplast DNA decatenation that is mediated by human TOP2α and TOP2β in vitro with IC50 of 2.8 and 0.42 uM, respectively. |
1151668-24-4 |
DC22037 |
Bobcat339
Featured
Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a. |
2280037-51-4 |
DC23218 |
BOC-D-FMK
Featured
BOC-D-FMK is a cell-permeable, irreversible, broad spectrum caspase inhibitor, inhibits apoptosis stimulated by TNF-α with IC50 of 39 uM. |
634911-80-1 |
DC20034 |
Boc-MLF TFA
Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations. |
|
DC8073 |
Bohemine
Featured
Bohemine is a synthetic, cell-permeable, cyclin-dependent kinase inhibitor. |
189232-42-6 |
DC21869 |
Borussertib
Featured
Borussertib is a potent, first-in-class, covalent-allosteric AKT inhibitor. |
1800070-77-2 |
DC12405 |
BOS172722
Featured
BOS172722 (BOS-172722) is a potent, selective MPS1 kinase inhibitor with biochemical IC50 of 11 nM, 100-fold selectivity over CDK2. |
1578245-44-9 |
DC5164 |
Bosutinib (SKI-606)
Featured
Bosutinib is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity. |
380843-75-4 |
DC23896 |
Box5
Box5 is a Wnt5a-derived N-butyloxycarbonyl hexapeptide (t-Boc-Met-Asp-Gly-Cys-Glu-Leu), acts as an Wnt5a antagonist. |
881188-48-3 |
DC20322 |
BPIPP
BPIPP is an inhibitor of GC-C (guanylyl cyclase type C) that inhibits stimulation of guanylyl cyclase and adenylyl cyclase, suppresses cGMP accumulation in a variety of cell lines (IC50=3.4-11.2 uM). |
325746-94-9 |
DC12608 |
BPN14770
Featured
BPN14770 (BPN-14770) is an allosteric inhibitor of phosphodiesterase 4D (PDE4D) with IC50 of 7.8 and 7.4 nM for human PDE4D7 and PDE4D3 respectively, displays 16-fold less potent against monomeric form of PDE4D lacking the UCR1 dimerization domain (PDE4D2 |
1606975-12-5 |
DC23884 |
BPN-15606
BPN-15606 (BPN15606) is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 by SHSY5Y neuroblastoma cells with IC50 of 7 nM. |
1914989-49-3 |
DC8294 |
BPR1J-097
Featured
BPR1J-097 is a novel small molecule FLT-3 inhibitor(IC50=11±7 nM) with promising in vivo anti-tumour activities; inhibits FLT-3 D835Y with an IC50 of 3 nM. |
1327167-19-0 |
DC21870 |
BPR1J373
BPR1J373 is a potent, orally available multitargeted kinase inhibitor, potently inhibits FLT3, c-KIT, VEGFR1-3, Aurora A, PDGFRα, PDGFRβ, RET, and SRC with IC50 values of <100 nM. |
|
DC20825 |
BPR1K653
BPR1K653 is a novel potent Aurora kinase inhibitor that inhibits Aurora-A and Aurora-B with IC50 of 24 nM and 45 nM, respectively. |
1192754-06-5 |
DC7951 |
Glutaminase Inhibitor II, BPTES
Featured
BPTES is a selective inhibitor of Glutaminase GLS1 (KGA) |
314045-39-1 |