CYH33 (CYH-33) is a novel potent, PI3Kα-selective inhibitor with IC50 of 5.9 nM/598 nM/ 78.7 nM/225 nM aginst class I PI3K isoform α/β/δ/γ, respectively.

CYH33 (CYH-33) is a novel potent, PI3Kα-selective inhibitor with IC50 of 5.9 nM/598 nM/ 78.7 nM/225 nM aginst class I PI3K isoform α/β/δ/γ, respectively.

CYP11B1-IN-25 is a selective, potent 11β-hydroxylase (CYP11B1) inhibitor with IC50 of 2 nM, displays 14-fold selectivity over CYP11B2.

Cytidine

Cytochalasin H is a potent inhibitor of actin incorporation into filaments,a cell-permeable fungal toxin used in actin polymerization studies and cytological research.

CZC24832 is the first selective PI3Kγinhibitor with IC50 of 27 nM, with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3Kα and PI3Kδ.

D-(+)-Cellobiose is a substrate of β-glucosidase.

D-(+)-Trehalose dihydrate can be used as a food ingredient and pharmaceutical excipient.

D,L-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis.

D13-9001 (D 13-9001) is a small molecule, MexAB-OprM specific efflux pump inhibitor with good potency in vitro (MPC 2 ug/mL) and displays excellent activity in vivo in a rat pneumonia model of P. aeruginosa..

D156844 is a potent SMN2 inducer and DcpS inhibitor.

D159153 (D-159153) is a novel potent, allosteric inhibitor of PDE4 with cellular IC50 of 28.5 and 6.6 nM for PDE4B1 and PDE4D3, respectively..

D159687 is a selective negative allosteric modulator (NAM) of PDE4D.

D3263 is a novel, orally bioavailable small molecule Trp-p8 agonist.

D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and d

D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-Tubulin.

DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptors, in mitochondrial fractions of the rat brain.

Dafadine A is the first reported small-molecule DAF-9 cytochrome P450 inhibitor that robustly induces dauer formation in in the nematode Caenorhabditis elegans.

Dagrocorat (PF 00251802) is a potent, selective high-affinity dissociated agonist of the glucocorticoid receptor..

Daidzin is a potent, selective aldehyde dehydrogenase 2 (ALDH2,IC50 = 80 nM) inhibitor, which has antiallergic anti-oxidant, anti-carcinogenic, antithrombotic,and anti-atherosclerotic activities

Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM.

Damnacanthal is a highly potent, selective inhibitor of p56 lck tyrosine kinase with IC50 of 17 nM for inhibition of p56lck autophosphorylation.