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Cat. No. Product name CAS No.
DC12516 DB550

DB550 (DB-550) is a potent, peptidomimetic of calcium-inducing domain (CID) that disrupts the CD95-PLCγ1 interaction without affecting the CD95-FADD interaction binds to SH3-PLCγ1 with Kd of 40.7 uM.

DC12517 HT105

DB550 (DB-550, TCWKHRK) is a potent, peptidomimetic of calcium-inducing domain (CID) that disrupts the CD95-PLCγ1 interaction, abrogates the CD95-mediated Ca2+ response in mouse PBLs with IC50 of 38 nM.

DC22069 DB818 Featured

DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence.

790241-43-9
DC21882 DBCO acid 1

DBCO acid 1 is a Click Chemistry intermidate used for antibody-drug conjugates..

1353016-70-2
DC21883 DBCO acid 2

DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates..

1207355-31-4
DC21884 DBCO acid 3

DBCO acid 3 is a Click Chemistry intermidate used for antibody-drug conjugates..

1425485-72-8
DC21885 DBCO acid 4

DBCO acid 4 is a Click Chemistry intermidate used for antibody-drug conjugates..

1618102-42-3
DC21886 DBCO acid 5

DBCO acid 5 is a Click Chemistry intermidate used for antibody-drug conjugates..

1337920-25-8
DC21888 DBCO intermidate 1

DBCO intermidate 1 is a Click Chemistry intermidate used for antibody-drug conjugates..

23112-88-1
DC21889 DBCO intermidate 2

DBCO intermidate 2 is a Click Chemistry intermidate used for antibody-drug conjugates..

23194-93-6
DC21890 DBCO intermidate 3 Featured

DBCO intermidate 3 is a Click Chemistry intermidate used for antibody-drug conjugates..

1369862-03-2
DC21891 DBCO Maleimide

DBCO Maleimide is a Click Chemistry intermidate used for antibody-drug conjugates..

1395786-30-7
DC20355 DBCO-NHS ester 2

DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry.

1384870-47-6
DC22076 DBCO-NHS ester 3

DBCO-NHS ester 3 (DIBAC-NHS) is a Click Chemistry intermidate used for antibody-drug conjugates..

1393350-27-0
DC21987 DBCO-PEG4 amine

DBCO-PEG4 amine (ADIBO-PEG4-amine) is a Click Chemistry intermidate used for antibody-drug conjugates..

1255942-08-5
DC7602 DBeQ Featured

DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM.

177355-84-9
DC21892 dBET23

dBET23 is a BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=50 nM) in cellular degradation assays..

1957234-83-1
DC21893 dBET57 Featured

dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=500 nM), but is inactive on BRD4 BD2..

1883863-52-2
DC12665 DBPR114 Featured

DBPR114 is a quinazoline-based multi-kinase inhibitor for the treatment of acute myeloid leukemia and other solid tumors.

DC23976 DC_517

DC_05 is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases.

500017-70-9
DC23977 DC-05 Featured

DC-05 is a selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 10.3 uM, displays 3.6-fold selectivity over PRMT1 and >15-fold over DNMT3A, DNMT3B, G9a, SUV39H1, MLL1, SET7/9..

890643-16-0
DC20945 DC_AC50 Featured

DC_AC50 (DCAC50) is a small molecule that inhibits the human copper chaperones Atox1 and CCS (Kd=6.8 and 8.2 uM), blocks copper trafficking and significantly attenuates cancer cell proliferation.

497061-48-0
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