| DC71415 |
Cyclic HPMPC |
Cyclic HPMPC is a potent antiviral agent. Cyclic HPMPC can increase arterial oxygen saturation levels in lethal vaccinia virus (IHD strain)-infected mice. Cyclic HPMPC improves the outcome of congenital guinea pig cytomegalovirus (GPCMV) infection and decreases viral replication in guinea pig model. |
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| DC71416 |
γ-L-Glutamyl-S-allyl-L-cysteine |
γ-L-Glutamyl-S-allyl-L-cysteine is a naturally occurring organosulfur compound found in garlic. |
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| DC71417 |
YSK 05
Featured
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YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo. |
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| DC71418 |
BPC157
Featured
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BPC157 (Bepecin, PL 14736), a small, chemically synthesised pentadecapeptide and a partial sequence of the human gastric juice protein BPC, which has been shown to be safe in clinical trials for inflammatory bowel disease and may be able to cure intestinal anastomosis dehiscence. |
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| DC71419 |
Dammarenediol II |
Dammarenediol II (Compound 3) is a compound isolated from the resin of Boswellia freerana. |
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| DC71420 |
Cannabisin B |
Cannabisin B (Compound 7) is a compound isolated from the aerial part of Tetragonia tetragonioides (New Zealand spinach). |
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| DC71421 |
Xanthine-15N2 |
Xanthine-15N2 is a 15N-labeled Lauroyl-L-carnitine (chloride). |
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| DC71422 |
(R)-1-PeCSO |
(R)-1-PeCSO (trans-(+)-S-1-Propenyl-L-cysteine sulfoxide) is the most abundant flavor precursor in onions. |
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| DC71423 |
6bK |
6bK is a potent and selective insulin degrading enzyme (IDE) inhibitor with an IC50 value of 50 nM. 6bK increases circulating insulin in high-fat-fed mice. Acute administration of 6bK enhances glucose tolerance to oral glucose, notably to a greater extent in high-fat-fed mice. |
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| DC71424 |
MT-VC-ZD02044 |
MT-VC-ZD02044 is a cytotoxic and anti-mitotic agent. |
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| DC71425 |
TCS1105 |
TCS1105 is a benzodiazepine ligand with agonist for α2-subunit containing GABAA receptors and antagonist for α1-subunit containing GABAA receptors. TCS1105 reduces anxiety-like behavior in mice. TCS1105 enhances offensive behavior and social dominance. TCS1105 blocks Sema3A induced AGC (axonal growth cones) collapse in a concentration-dependent fashion. |
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| DC71426 |
Fmoc-Glu(OtBu)-OH-15N |
Fmoc-Glu(OtBu)-OH-15N is a 15N-labeled Fmoc-L-Val-OH. |
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| DC71428 |
Fissitungfine B |
Fissitungfine B is a compound extracted from the tropical medicinal plant Fissistigma tungfangense. Fissitungfine B has strong anticancer activity. |
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| DC71429 |
Fmoc-Pro-OH-15N |
Fmoc-Pro-OH-15N is a 15N-labeled Glycine ethyl ester monohydrochloride. |
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| DC71430 |
NHS-NH-(diethylamino)ethyl benzoate
Featured
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NHS-NH-(diethylamino)ethyl benzoate is a compound that can be used for N-glycan labeling. |
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| DC71431 |
1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate |
1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate is a PEG lipid. 1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate can be used for researching drug delivery. |
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| DC71432 |
Photosensitizer-2 |
Photosensitizer-2 (compound 1) is a organic D-π-A sensitizer against phototoxicity. Photosensitizer-2 contains an acrylic acid moiety that exerts high levels of phototoxicity. Photosensitizer-2 shows antitumor activity against HeLa cells, with IC50 values of 20.9 ± 4.5 μM (dark) and 0.046 ± 0.012 μM (irradiation), respectively. |
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| DC71433 |
ThioD |
ThioD is a protein linker with a hydrophobic thioester. |
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| DC71434 |
SGC-AAK1-1N |
SGC-AAK1-1N is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor, with an IC50 of 1.8 μM. |
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| DC71435 |
LRH-1 modulator-1 |
LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 shows anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces anti-inflammatory cytokine IL-10, and reduces inflammatory cytokine IL-1b and TNFa. |
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| DC71436 |
Grosshemin |
Grosshemin (Grosshemine) is a natural compound found in the Siberian population of Centaurea scabiosa. |
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| DC71437 |
Acridone-4-carboxylic acid |
Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM. |
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| DC71438 |
BB 0305179 |
BB 0305179 (compound 59) is a potent anti-prion agent, with an IC50 of 4.7 μM. BB 0305179 inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain . |
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| DC71439 |
O-Acetylgalanthamine |
O-Acetylgalanthamine, a acetylated alkaloid, is a natural product that can be isolated from Narcissus pseudonarcissus. |
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| DC71441 |
PAL-4 |
PAL-4 (compound 4) is a potent, selective and reversible Lysophospholipase-like 1 (LYPLAL1) activator with EC50 value of 0.39 μM and 0.49 μM for mice LYPLAL1 and huamn LYPLAL1, respectively. PAL-4 can be used for researching metabolic disorders. |
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| DC71442 |
Cepharanoline |
Cepharanoline is a compound isolated from Stephania cepharantha Hayata. Cepharanoline has proliferative activities. |
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| DC71443 |
Nicomol |
Nicomol is an orally active hypolipidemic agent that can increase the high density lipoprotein cholesterol (HDL-C) level. Nicomol inhibits the rapid rise of plasma free fatty acids. |
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| DC71444 |
Lucenin-2 |
Lucenin-2 is a natural C-glucoside compound belonging to the flavonoid class. |
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| DC71445 |
Quercetin 3-O-rutinoside-7-O-glucoside |
Quercetin 3-O-rutinoside-7-O-glucoside (compound 8) is an antioxidant agent that canbe found in Hemerocallis fulva. Quercetin 3-O-rutinoside-7-O-glucoside shows strong lipid peroxidation inhibitory activities. |
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| DC71446 |
PEAQX |
PEAQX ((1RS,1'S)-PEAQX, NVP-AAM077) is an effective and orally available human NMDA antagonist, which shows preference in excess of 100-fold for hNMDA 1A/2A (IC50=of 270 nM) over hNMDA 1A/2B receptors (IC50=29,600 nM). |
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