DCC2827 |
Jmx0207 |
Novel inhibitor of viral protease function, suppressing Zika virus Infection both In vitro and In vivo |
|
DCC2828 |
Jmx0254 |
Novel Potent NS4B Inhibitor for the Treatment of Dengue Virus Infection |
|
DCC2829 |
Jmx0510-2 |
Novel Potent Human Adenovirus Inhibitor, showing improved anti-HAdV activity (IC50 = 0.27 μM), significantly decreasing cytotoxicity (CC50 = 156.8 μM), and lowering in vivo toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosam |
|
DCC2830 |
Jnj-1013 |
Novel potent and selective IRAK1 degrader, effectively degraded cellular IRAK1 protein with a DC50 of 3 nM in HBL-1 cells |
|
DCC2831 |
Jnj-10311795 |
Novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase |
|
DCC2832 |
Jnj-17029259 |
Vascular endothelial growth factor receptor-2 (VEGF-2) kinase inhibitor |
|
DCC2833 |
Jnj-17148066 |
Estrogen receptor ESR1 agonist |
|
DCC2834 |
Jnj-1930942 |
Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor |
|
DCC2835 |
Jnj-20788560 |
Selective delta opioid receptor agonist as a potent and efficacious antihyperalgesic agent |
|
DCC2836 |
Jnj-26076713 |
Novel EthR inhibitor, boosting antituberculous activity of ethionamide |
|
DCC2837 |
Jnj-28330835 |
Selective androgen receptor modulator with minimal prostate hypertrophic activity stimulating sexual behavior in female rats |
|
DCC2838 |
Jnj-28583867 |
Histamine H3 receptor antagonist and serotonin reuptake inhibitor |
|
DCC2839 |
Jnj-40068782 |
Novel potent, selective, and systemically active positive allosteric modulator (PAM) of mGlu2-receptors |
|
DCC2840 |
Jnj-40255293 |
Novel Adenosine A 2A /A 1 Antagonist With Efficacy In Preclinical Models of Parkinson's Disease |
|
DCC2841 |
Jnj-40264796 |
Negative control for JNJ-40068782 |
|
DCC2842 |
JNJ-40355003
Featured
|
JNJ-40355003 is a potent and selective atty acid amide hydrolase (FAAH) inhibitor. |
|
DCC2843 |
Jnj-40573663 |
Negaive control for JNJ-42396302 |
|
DCC2844 |
Jnj-40929837 |
Novel potent, orally active LTA4H inhibitor |
|
DCC2845 |
Jnj-42396302 |
Novel inhibitor of PDE10A |
|
DCC2846 |
Jnj-42491293 |
Novel ago-PAM for the metabotropic glutamate receptor subtype 2 (mGluR2) |
|
DCC2847 |
Jnj-49153390 |
Novel inhibitor of respiratory syncytial virus (RSV), binding the RSV F glycoprotein and inhibiting membrane fusion |
|
DCC2848 |
Jnj-53721590 |
Negative control for JNJ-54119936 |
|
DCC2849 |
Jnj-61432059 |
Novel TARP γ-8 Selective AMPAR Negative Modulator |
|
DCC2850 |
Jnj-dgat1-a |
Selective DGAT1 inhibitor |
|
DCC2851 |
Jnj-dgat2-b |
Selective DGAT2 inhibitor |
|
DCC2852 |
Jns 1-40 |
Novel cysteine-reactive covalent ligand, selectively targeting C377 of PPP2R1A to impair breast cancer signaling, proliferation, and in vivo tumor growth |
|
DCC2853 |
Jp1201 |
Novel SMAC mimetic, sensitizing non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner |
|
DCC2854 |
Jp4-039 |
Non-toxic radioprotector GS-nitroxide, improving hematopoiesis in long-term bone marrow cultures (LTBMCs) |
|
DCC2855 |
Jr-220 |
Non-toxic anti-relapse agent, acamprosate |
|
DCC2856 |
Jra-003 |
Novel selective inhibitor of nuclear translocation of IKKα as the most potent synthetic gibberellin against cancer-derived cell lines, displaying no cytotoxicity in cells derived from noncancerous sources (HEK 293T, HS 578BST, HS 888Lu, HS 895Sk, HUVEC) |
|