DCC4420 |
rhm-138 |
Selective sigma-2 ligand, inducing apoptosis in EMT-6 breast cancer cells |
|
DCC4421 |
Rhodblock 1a |
Potent inhibitor of the Rho pathway |
|
DCC4422 |
Ricasetron |
Selective antagonist of the serotonin 5-HT3 receptor |
|
DCC4423 |
Rifametane |
Antibiotic for tuberculosis (TB) treatment |
|
DCC4424 |
Rifamycin Sv |
Natural antibiotic, inhibiting prokaryotic DNA-dependent RNA synthesis and protein synthesis; blocking RNA-polymerase transcription initiation, modulating ß2m aggregation |
|
DCC4425 |
Rilmazafone |
Water-soluble benzodiazepine prodrug, as a sedative and hypnotic neuropsychiatric agent |
|
DCC4426 |
Rilpivirine Hydrochloride |
HIV-1 reverse transcriptase inhibitor, also acting as an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor |
|
DCC4427 |
R-imeglimin |
Novel antidiabetic agent, impairing glucose uptake by muscle tissue, excessing hepatic gluconeogenesis, and increasing beta-cell apoptosis |
|
DCC4428 |
Rinoxiab |
Natural inducer of apoptosis by significantly upregulating Bcl-2, mitigating expression of Bcl2 in HCT 15 cells and attenuating the apoptotic markers and cell cycle regulatory proteins |
|
DCC4429 |
Rip2-in-3 |
First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific inhibitor |
|
DCC4430 |
Ripk2 Protac 20 |
Novel IAP-based selective RIPK2 degrader |
|
DCC4431 |
Rivoglitazone Hydrochloride |
Novel peroxisome proliferator-activated receptor gamma (PPARgamma) agonist |
|
DCC4432 |
Rjr-2403 Fumarate |
Highly selective α4β2 subtype nicotinic receptor agonist |
|
DCC4433 |
Rjw100 |
Novel potent Liver Receptor Homolog-1 (LRH-1) modulator |
|
DCC4434 |
Rk-0404678 |
Novel inhibitor of dengue virus NS5 RNA-dependent RNA polymerase (RdRp), inhibiting the DENV type 2 (DENV2) RdRp activities |
|
DCC4435 |
Rk-682 |
Natural selective inhibitor of protein tyrosine phosphatases (PTPases) |
|
DCC4436 |
Rk-9123016 |
Novel potent and selective SIRT2 inhibitor, increasing the acetylation level of eukaryotic translation initiation factor 5A (eIF5A) and reducing cell viability of human breast cancer cells accompanied with a decrease in c-Myc expression |
|
DCC4437 |
Rkn5755 |
Novel selective inhibitor of activated fibroblasts, inhibiting the enhanced migration of fibroblasts cocultured with cancer cells by binding to β-arrestin1 and interfering with β-arrestin1-mediated cofilin signaling pathways |
|
DCC4438 |
Rl-338 |
Novel potent and highly selective GPR6 inverse agonist, inhibiting GPR6 cAMP signalling in TR-FRET assays with a EC50 = 16 nM and >100 fold selectivity against GPR3 and GPR12 |
|
DCC4439 |
Rm-131 |
Novel gastrocolokinetic ghrelin agonist, approximately sixfold greater potency than natural ghrelin |
|
DCC4440 |
Rm-133 |
Promising pro-apoptotic agent, showing activity on various cancer cell lines |
|
DCC4441 |
Rm1490 |
Novel MOR agonist |
|
DCC4442 |
Rm-581-fluo |
Novel Fluorescent ER-Tracker dye, showing potent cytotoxic activity on several types of cancer cells, being accumulated into the endoplasmic reticulum (ER) as highlighted by its colocalization |
|
DCC4443 |
Rms-07 |
The first irreversible covalent MPS1 inhibitor, targeting a poorly conserved cysteine in the kinase's hinge region |
|
DCC4444 |
rn-450 |
Potent, reversible, non-carbonyl inhibitor of fatty acid amide hydrolase (FAAH) |
|
DCC4445 |
Rna Ligand Tppc |
Novel potent and specific RNA-binding ligand, targeting riboswitches and other RNAs at proximal subsites |
|
DCC4446 |
Ro 04-5595 Hydrochloride |
Selective antagonist of NMDA receptors NR2B subunits |
|
DCC4447 |
ro 115-1240 |
Selective alpha1A/1L-adrenoceptor partial agonist |
|
DCC4448 |
Ro 25-6981 Benzoate |
Potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit |
|
DCC4449 |
Ro 31-8220 |
Potent protein kinase C (PKC) inhibitor |
|