| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC74008 | GSK898 | GSK898 is a potent, highly selective kynurenine monooxygenase (KMO) inhibitor with pIC50 of 8.8. |
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| DC74009 | H3B-616 | H3B-616 (H3B 616) is a potent, selective allosteric inhibitor of CPS1 with IC50 of 66 nM, demonstrates no appreciable inhibition of CPS2 (IC50>100 uM). |
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| DC74010 | HB-MIX1902 Supplement (10X) | HB-MIX1902 Supplement (10X) is an optimized serum-free supplement used to promote and maintain the growth, maturity and viability of iPS-derived hepatic and biliary cells. MIX1902 is provided as a 10X liquid and is intended to be used with Hepatocyte Cult |
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| DC74011 | HJ445A | HJ445A is a highly potent, selective myoferlin (MYOF) inhibitor, binds to MYOF-C2D domain with KD value of 0.17 uM. |
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| DC74012 | HP661 | HP661 is a potent, and selective oral complex I OXPHOS inhibitor with 76% inhibition at 1u M in H460 cells using electron flow assays, inhibits high-OXPHOS H460 cell viability with IC50 of 5 nM. |
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| DC74013 | HPK1 PROTAC SS44 | HPK1 PROTAC SS44 is a heterobifunctional small molecule based on ZYF0033 that simultaneously binds HPK1 and E3 ligase Cereblon (CRBN), induces degradation of HPK1. |
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| DC74014 | HQY426 | HQY426 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.32 uM, exhibits potent antitumor activity. |
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| DC74015 | HQY436 | HQY436 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.15 uM, exhibits potent antitumor activity. |
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| DC74016 | HsClpP activator ZK53 | HsClpP activator ZK53 is a potent, selective activator of mitochondrial caseinolytic protease P (HsClpP) with EC50 of 0.22 uM in FI-based protease activity assays, inactive toward bacterial ClpP proteins. |
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| DC74017 | HTL0041178 Featured | HTL0041178 is a potent GPR52 agonist with EC50 of 27.5 nM (human or rat GPR52). |
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| DC74018 | HTS13286 | HTS13286 is a selective AQP9 inhibitor with IC50 of 1.5 uM (inhibition of CHO-AQP9 cell water permeability). |
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| DC74019 | HYGIC | HYGIC is a small molecule that simultaneously induces hypocotyl elongation and thickening via the ethylene signaling pathway activated by endogenous ethylene. |
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| DC74020 | I194496 | I194496 (I 194496) is a novel potent, selective inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 0.79 uM. |
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| DC74021 | IBS007125 | IBS007125 is a small molecule inhibitor of c-Maf, inhibits multiple myeloma proliferation by targeting cMaf transcriptional activity. |
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| DC74022 | IDE-397 Featured | IDE-397 (GSK-4362676, GSK-676) is a potent, selective small molecule methionine adenosyltransferase 2a (MAT2A) inhibitor, displays broad anti-tumor activity across a panel of MTAP-deleted patient-derived xenografts. |
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| DC74023 | IGGi-11 | IGGi-11 is a first-in-class small molecule inhibitor of non-canonical activation of heterotrimeric G-protein signaling, binds to G-protein α-subunits (Gαi, Gαi3 ITC Kd=4 uM), specifically disrupts their engagement with GIV/Girdin. |
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| DC74024 | IGGi-11me | IGGi-11me is a specific, cell-active small molecule inhibitor of GIV-dependent G-protein cell signaling, binds to G-protein α-subunits, specifically disrupts their engagement with GIV/Girdin. |
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| DC74025 | IMB0901 | IMB0901 is a small molecule myostatin (MSTN) inhibitor that inhibits the MSTN promoter activity, the MSTN signaling pathway, and the MSTN positive feedback regulation. |
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| DC74026 | INH-12 | INH-12 is a selective small-molecule HSD17B12 inhibitor with 70% inhibition of HSD17B12 activity to transform estrone (E1) into estradiol (E2) at 1 uM, reduces the replication of Flaviviridae viruses (HCV, DENV and ZIKV). |
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| DC74027 | InhiTinib | InhiTinib is a small molecule that inhibit interferon (IFN)-gamma production (IC50=52.44 nM) and proliferation of primary CD3+ T cells without inducing cell death. |
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| DC74028 | INI-60 | INI-60 (Inhibitor of Nuclear Import-60) is a novel small molecule inhibitor of Kpnβ1-mediated nuclear import with anti-cancer activity. |
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| DC74029 | IOI-214 | IOI-214 is a potent inhibitor of LPS-induced inflammatory cytokine production, prevent HF diet-induced NAFLD/MAFLD in vivo. |
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| DC74030 | IOI-42 | hPEBP4 inhibitor IOI-42 is a small molecule inhibitor of anti-apoptotic protein hPEBP4, potentiates TNF-α-mediated growth inhibition of MCF-7 breast cancer cells. |
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| DC74031 | IPA | IPA (Inhibitor of Priming Activity) is a small-molecule compound that binds Sec18 (Kd=3.84 uM) and blocks SNARE activation, inhibits vacuole fusion at the SNARE priming stage with IC50 of 50 uM. |
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| DC74032 | IP-DNQ | IP-DNQ (Isopentyl-deoxynboquinone) is a small molecule that selectively kills pancreatic ductal adenocarcinoma cells in an NQO1-dependent manner. |
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| DC74033 | Ipfencarbazone | Ipfencarbazone is a substance being developed for the control of weeds such as watergrass in rice, herbicide agent. |
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| DC74034 | IPHBA | IPHBA is a small-molecule inhibitor that suppresses EPAS1-driven IL-31 induction, selectively inhibits TCR-mediated IL-31 induction in murine CD4+ T cells with IC50 of 10.6 uM. |
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| DC74035 | Ironomycin | Ironomycin (Ironomycin AM5) is a lysosomal iron-targeting small molecule that reduces the mitochondrial iron load, resulting in the potent disruption of mitochondrial metabolism. |
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| DC74036 | iSB09 | iSB09 is a potent, selective small moelcule abscisic acid (ABA) receptor agonist with HAB1 IC50 value of 316 nM (combined with the engineered CsPYL1 ABA receptor CsPYL15m). |
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| DC74037 | JA310 | JA310 is a potent, highly selective inhibitor of the mammalian sterile 20-like serine/threonine (MST) family member MST3 (STK24) with ITC KD value of 115 nM. |
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