| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC73978 | DS07551382 | DS07551382 (DS 07551382) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1), suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
|
| DC73979 | DS21150768 | DS21150768 is a potent selective and orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with IC50 of 3.27 nM in cell-free HPK1 assays, binds to HPK1 with an affinity constant (KD) of 6.08 nM. |
|
| DC73980 | DS55980254 Featured | DS55980254 (DS 55980254) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1) inhibitor, suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
|
| DC73981 | DS68591889 | DS68591889 (PTDSS1i) is a potent, selective phosphatidylserine synthase 1 (PTDSS1) inhibitor, highly sellective over PTDSS2, induces phospholipid imbalance in a wide range of cancer cells. |
.gif)
|
| DC73982 | DSHN-OMe | DSHN-OMe (DSHN methyl ester) is a small molecule modulator of NR0B2, effectively reduces induction of LXR target gene ABCA1 by GW3965 (1 uM) in BMDMs with IC50 of 3.8 uM, reduces regulatory T cell expansion and impede breast cancer progression. |
|
| DC73983 | DSK638 | DSK638 (DSK-638) is a potent small moelcule RECK inducer, binds histone deacetylases (HDACs) with IC50 of 5-10 uM for HDAC1/3. |
|
| DC73984 | DSRM-3716 | DSRM-3716 (DSRM3716, 5-iodoisoquinoline) is a potent and selective inhibitor of NADase SARM1 with IC50 of 75 nM, displays selectivity against various NAD metabolizing and pathway enzymes (e.g., NAMPT and NMNAT). |
|
| DC73985 | Ederimotide | Ederimotide (WT1-A1) is a synthetic peptide derived from nonamer sequences of the Wilms tumor protein 1 (WT1), increases human T-cell responses and shows potential as cancer vaccine. |
|
| DC73986 | EML417 | EML417 is a small molecule that selectively interactes with the Tudor domain of PHF20. |
|
| DC73987 | Endosidin17 | Endosidin17 (ES17) is a small molecule targets retromer component VPS35, binds to VPS35 Impairs interaction with RABG3f, causes dose-dependent stabilization of VPS35 with EC50 of 0.9 uM. |
|
| DC73988 | EP055 | EP055 (EP-055) is a small molecule that targets EPPIN on the surface of sperm and inhibits motility (IC50=199.5 uM, CASA assay using human sperm), binds to the C-terminal domain of EPPIN. |
|
| DC73989 | EPIC-0412 | EPIC-0412 is a small-molecule inhibitor that enhances the chemotherapeutic effect of temozolomide (TMZ) by acting on the p21-E2F1 DNA damage repair axis and ATF3-p-p65-MGMT axis. |
|
| DC73990 | Equilin | Equilin (7-Dehydroestrone) is a highly potent 3βHSD1 inhibitor with IC50 of 2.8 nM in VCaP cells, also inhibits the activity of purified 3βHSD1 with SPR KD of 2.23 uM. |
|
| DC73991 | Ethanimidothioic acid | Ethanimidothioic acid (R5421) is an inhibitor of platelet scramblase activity. |
|
| DC73992 | EVT-701 | EVT-701 is a highly potent, selective, and safe mitochondrial complex 1 (MC1) inhibitor, reduces NADH abundance with IC50 of 300 nM. |
|
| DC73993 | F12511 | Eflucimibe (F 12511) is a highly potent, selective inhibitor of acyl-CoA: cholesterol acyltransferase ( ACAT/SOAT) with IC50 of 3, 7, and 71 nM in whole cell assays using HepG2, CaCo-2 and THP-1 cell lines, respectively. |
|
| DC73994 | F759 | F759 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets. |
|
| DC73995 | F83236 | F83236 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets. |
|
| DC73996 | FDW028 | FDW028 is a potent and highly selective small-molecule inhibitor of fucosyltransferase 8 (FUT8) with binding KD value of 5.486 uM, displays no affinity against other FUTs, shows potent anti-CRC activities. |
|
| DC73997 | Feeblin | Feeblin (SLC15A4 inhibitor C5) is a small molecule inhibitor of the proinflammatory TLR7/8/9-IRF5 pathway (IC50=1.6 uM) by disrupting the SLC15A4-TASL adapter module, Feeblin is an IRF5 pathway-specific inhibitor. |
|
| DC73998 | FK3453 | FK3453 (FK 3453) is a novel inhibitor of thymic stromal lymphopoietin (TSLP) production, reduces both TSLP protein levels and mRNA levels both in vitro and in vivo. |
|
| DC73999 | FMP-201300 | FMP-201300 is a potent, selective and allosteric inhibitor of the unique valine gatekeeper mutants of IP6K1 and IP6K2 with IC50 of 114/190 nM for IP6K1 L210V and IP6K2 L210V mutants respectively. |
|
| DC74000 | GCN2iA | GCN2iA is a potent seletive inhibitor of general control nonderepressible 2 (GCN2) with IC50 of 4.0 nM. |
|
| DC74001 | GE1111 | GE1111 is a novel potent small molecule Mas-related G protein-coupled receptor X2 (MRGPRX2) antagonist, significantly inhibits mast cells degranulation and MRGPRX2 activation with IC50 of 5 uM. |
|
| DC74002 | GMFBI.1 | GMFBI.1 is a small molecule that specifically block Ser83 phosphorylation site on Glia maturation factor-β (GMF-β), directly binds to hGMF-β protein with Kd of 19.9 uM. |
|
| DC74003 | GNE-1858 | GNE-1858 (GNE1858) is a potent, selective, ATP-competitive inhibitor of HPK1 with IC50 of 1.9 nM in the SLP76 phosphorylation assay. |
|
| DC74004 | GNF362 | GNF362 (GNF-362) is a highly potent, selective inhibitor of inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) with IC50 of 9 nM. |
|
| DC74005 | GNF-9228 | GNF-9228 is a small molecule that stimulates human β-cell proliferation, selectively activates human β-cell relative to α- or δ-cell proliferation. |
|
| DC74006 | GO-203 | GO-203 (GO203) is a cell-penetrating peptide inhibitor of mucin-1-cycloplasmic C-terminal subunit (MUC1-C), blocks homodimerization of the MUC1-C subunit required for nuclear translocation and downstream signaling. |
|
| DC74007 | GQ352 | GQ352 is a small molecule Gαq/11 inhibitor, directly binds to the Gαq and inhibits the dissociation of Gαβγ heterotrimers with IC50 value of 8.9 uM. |
|
