Cat. No. | Product name | CAS No. |
DC10456 |
STF-62247
Featured
STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM). |
315702-99-9 |
DCAPI1445 |
strontium ranelate
Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Commonly used as an antiosteoporotic. |
135459-87-9 |
DC7302 |
SU14813
Featured
SU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet-derived growth factor receptors (PDGFR), Kit, and fms-like tyrosine kinase 3 (FLT-3). |
627908-92-3 |
DC5079 |
Orantinib (TSU-68)
Featured
SU6668 has greatest potency against PDGFR autophosphorylation with Ki of 8 nM, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. |
252916-29-3 |
DC6906 |
Aprepitant (MK-0869, L-754030)
Featured
Substance P antagonists (SPA). |
170729-80-3 |
DC10581 |
Succinobucol(AGI 1067)
Featured
Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. |
216167-82-7 |
DC9732 |
Sufugolix(TAK-013)
Featured
Sufugolix(TAK-013) is a non-peptide, orally-active, selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (IC50 = 0.1 and 0.06 nM for affinity and in vitro inhibition, respectively). |
308831-61-0 |
DC3145 |
Sunitinib base
Featured
Sunitinib Malate (Sutent, SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. |
557795-19-4 |
DCAPI1388 |
Suplatast tosylate
Suplatast tosylate |
94055-76-2 |
DC10733 |
Sutezolid (PNU-100480)
Featured
Sutezolid (PNU-100480) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis. |
168828-58-8 |
DC5017 |
Suvorexant
Featured
Suvorexant (MK-4305) is a potent, selective, and orally bioavailable antagonist of OX1R and OX2R currently under clinical investigation as a novel therapy for insomnia. |
1030377-33-3 |
DC8852 |
SW-044248
Featured
SW-044248 is a Novel Inhibitor of Topoisomerase I Is Selectively Toxic for a Subset of Non-Small Cell Lung Cancer Cell Lines. |
522650-83-5 |
DC8308 |
SYM2206
SYM2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50 = 2.8 μM ). |
173952-44-8 |
DC5105 |
Favipiravir (T-705)
Featured
T 705(Favipiravir) is a RNA-directed RNA polymerase NS5B inhibitor.T 705(Favipiravir) is useful for Antiviral agents. |
259793-96-9 |
DC9842 |
T0901317
Featured
T0901317 is a potent, high affinity liver X receptor (LXR) agonist (EC50 ~ 50 nM, Kd values are 7 and 22 nM for LXR-α and LXR-β respectively). |
293754-55-9 |
DC8024 |
T-5224
Featured
T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1, attenuates lipopolysaccharide-induced liver injury in mice. |
530141-72-1 |
DC5901 |
Tadalafil
Featured
Tadalafil is a potent and selective inhibitor of Phosphodiesterase-5 (PDE5) This compound prevents the breakdown of phosphodiesterases, many of which are used as secondary messengers. By preventing the breakdown of these messenger molecules, tadalafil can |
171596-29-5 |
DC7945 |
TAK-063
Featured
TAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs. |
1238697-26-1 |
DC11208 |
TAK-071
Featured
TAK-071 is a novel, potent and highly selective muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM. |
1820812-16-5 |
DC9311 |
Serabelisib(TAK-117,INK1117,MLN1117)
Featured
TAK-117(INK1117,MLN1117) is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha isoform with potential antineoplastic activity. |
1268454-23-4 |
DC11633 |
TAK-243
Featured
TAK-243 (MLN-7243, AOB87172) is a small-molecule, cell-permeable inhibitor of ubiquitin-activating enzyme E1 (UAE1). |
1450833-55-2 |
DC7306 |
TAK-438
Featured
TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. |
1260141-27-2 |