Cat. No. | Product name | CAS No. |
DC7376 |
BMS777607
Featured
BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM. |
1025720-94-8 |
DC7868 |
AS703026(Pimasertib)
Featured
AS703026(Pimasertib) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. |
1236699-92-5 |
DC7421 |
GO 6976
Featured
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3. |
136194-77-9 |
DC10034 |
GLPG0187
Featured
GLPG0187 is a small molecule integrin receptor antagonist (IRA) with potential antineoplastic activity. |
1320346-97-1 |
DC11089 |
TAS-120 (Futibatinib)
Featured
TAS-120 is a highly potent and selective irreversible FGFR inhibitor, effective in tumors harboring various FGFR gene abnormalities. |
1448169-71-8 |
DC26121 |
FOY-251 mesylate
Featured
FOY 251 is a metabolite of Camostat and a pollen protease inhibitor for prevention and control of allergy. |
71079-09-9 |
DC8860 |
Vorapaxar
Featured
Vorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM. |
618385-01-6 |
DC9514 |
Deforolimus
Featured
Deforolimus(AP23573; MK-8669; Ridaforolimus) is a selective mTOR inhibitor with IC50 of 0.2 nM; while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. IC50 value: 0.2 nM [1] Target: mTOR in vitro: Treatment of HT |
572924-54-0 |
DCAPI1551 |
Tacalcitol
Featured
Tacalcitol is a synthetic vitamin D3 analog. This compound has been shown to regulate calcium levels and induce nerve growth factor production in epidermal keratinocytes. Additionally, Tacalcitol has been noted to promotes normal bone development by regul |
57333-96-7 |
DC10475 |
Grapiprant
Featured
Grapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2) |
415903-37-6 |
DC10320 |
Saroglitazar (Magnesium)
Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. |
1639792-20-3 |
DC10322 |
Saroglitazar
Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. |
495399-09-2 |
DC7666 |
MK0752
Featured
MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2. |
471905-41-6 |
DC10109 |
Q203
Featured
Q203 is a promising new clinical candidate for the treatment of tuberculosis. |
1334719-95-7 |
DC11450 |
Selpercatinib(LOXO-292)
Featured
Selpercatinib is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 163, has an IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively. Antineoplastic activity. |
2152628-33-4 |
DC8142 |
TAS-116
Featured
TAS-116 is a highly selective inhibitor of heat shock protein 90α and β, demonstrates potent antitumor activity and minimal ocular toxicity in preclinical models. |
1260533-36-5 |
DC8901 |
Azilsartan medoxomil
Featured
Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. |
863031-21-4 |
DC5080 |
Belnacasan (VX-765)
Featured
VX-765 is a novel Caspase-1 inhibitor with an IC 50 of 0.8nM being investigated for the treatment of epilepsy, currently being developed by Vertex. |
273404-37-8 |
DC7622 |
BIBX1382
Featured
BIBX 1382 is a potent, selective inhibitor of EGFR tyrosine kinase (IC50 = 3 nM); displays > 1000-fold lower potency against ErbB2 (IC50 = 3.4 μM) and a range of other related tyrosine kinases (IC50 > 10 μM). |
196612-93-8 |
DC26133 |
Camostat mesylate
Featured
Camostat mesylate is a synthetic, orally bioavailable is a serine protease inhibitor. Used for the treatment of chronic pancreatitis. It attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. |
59721-29-8 |
DC7163 |
ZLN005
Featured
ZLN005 is a novel transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). |
49671-76-3 |
DC7488 |
RO4987655
Featured
RO4987655(CH-4987655) is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1/MEK1 IC50=5.2 nM), with potential antineoplastic activity. |
874101-00-5 |