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Saroglitazar (Magnesium)

  Cat. No.:  DC10320  
Chemical Structure
1639792-20-3
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Field of application
Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
Cas No.: 1639792-20-3
SMILES: CCO1[C@H](C([O-][Mg]12[O-]C([C@@H](O2CC)CC3=CC=C(OCCN4C(C)=CC=C4C5=CC=C(SC)C=C5)C=C3)=O)=O)CC6=CC=C(OCCN7C(C)=CC=C7C8=CC=C(SC)C=C8)C=C6.[MgH+]
Formula: C25H28NO4S.1/2Mg
M.Wt: 450.71
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
Description: In db/db mice, 12-day treatment with Saroglitazar (0.01-3 mg/kg per day, orally) causes dose-dependent reductions in serum triglycerides (TG), free fatty acids (FFA), and glucose. The ED50 for these effects is found to be 0.05, 0.19, and 0.19 mg/kg, respe
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC10322 Saroglitazar Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
DC10320 Saroglitazar (Magnesium) Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
DC8903 Troglitazone Troglitazone(CS-045), PPARγ agonist, is an anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity.
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