TAS-116
Cat. No.: DC8142
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Chemical Structure
1260533-36-5
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Field of application
TAS-116 is a highly selective inhibitor of heat shock protein 90α and β, demonstrates potent antitumor activity and minimal ocular toxicity in preclinical models.
| Cas No.: |
1260533-36-5 |
| Chemical Name: |
Pimitespib |
| Synonyms: |
PLO044MUDZ;Pimitespib;Tas 116;TAS116 pound>>TAS 116;BDBM126083;BCP25132;NSC780204;s7716;DB14876;SB17223;US8779142, 102;3-Ethyl-4-(3-(1-methylethyl)-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo(3,4-b)pyridin-1-yl)benzamide;3-ethyl-4-(3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)benzamide;3-ethyl-4-[;Tas-116;TAS 116，TAS116 |
| SMILES: |
O=C(C1C=CC(=C(C=1)CC)N1C2C(=C(C=CN=2)N2C=NC(C3C=NN(C)C=3)=C2)C(C(C)C)=N1)N |
| Formula: |
C25H26N8O |
| M.Wt: |
454.526943683624 |
| Sotrage: |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| Description: |
TAS-116 is a potent and selective HSP90α/β inhibitor with Kis of 34.7 nM, 21.3 nM, respectively. |
MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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