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Home > Inhibitors & Agonists > Proteasome/Ubiquitin > Heat Shock Protein (HSP)

TAS-116

  Cat. No.:  DC8142   Featured
Chemical Structure
1260533-36-5
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More than 5000 active chemicals with high quality for research!
Field of application
TAS-116 is a highly selective inhibitor of heat shock protein 90α and β, demonstrates potent antitumor activity and minimal ocular toxicity in preclinical models.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1260533-36-5
Chemical Name: Pimitespib
Synonyms: PLO044MUDZ;Pimitespib;Tas 116;TAS116 pound>>TAS 116;BDBM126083;BCP25132;NSC780204;s7716;DB14876;SB17223;US8779142, 102;3-Ethyl-4-(3-(1-methylethyl)-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo(3,4-b)pyridin-1-yl)benzamide;3-ethyl-4-(3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)benzamide;3-ethyl-4-[;Tas-116;TAS 116，TAS116
SMILES: O=C(C1C=CC(=C(C=1)CC)N1C2C(=C(C=CN=2)N2C=NC(C3C=NN(C)C=3)=C2)C(C(C)C)=N1)N
Formula: C25H26N8O
M.Wt: 454.526943683624
Sotrage: 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
Description: TAS-116 is a potent and selective HSP90α/β inhibitor with Kis of 34.7 nM, 21.3 nM, respectively.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC8142 TAS-116 TAS-116 is a highly selective inhibitor of heat shock protein 90α and β, demonstrates potent antitumor activity and minimal ocular toxicity in preclinical models.
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